Efficacy News and Research

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Novel bottom-up approach in synthetic immunology opens a new frontier for disease treatment

Synthetic immunology, an innovative field of research which could lead to fundamentally new approaches and methods in the treatment of infectious diseases and cancer, is the topic of an article in the "Perspectives" section of the journal "Nature Nanotechnology". Herein, Heidelberg researchers Prof. Dr. Kerstin Göpfrich, Prof. Dr. Michael Platten, Prof. Dr. Friedrich Frischknecht, and Prof. Dr. Oliver T. Fackler describe a so-called bottom-up approach that uses the toolbox of nanotechnology and synthetic biology to construct systems from molecular building blocks and specifically equip them with immune functions.

27 Aug 2024

New study shines light on the immune response to gonorrhea

A ground-breaking study involving Kenyan sex workers has shone a light into the immune response to gonorrhoea, paving the way for more effective vaccines.

27 Aug 2024

Semaglutide shown to cut major adverse cardiovascular events in heart failure patients

Semaglutide shows promise in reducing cardiovascular risks in obese patients with heart failure, improving outcomes in a recent large-scale clinical trial.

27 Aug 2024

Study identifies Gα13 as a key tumor suppressor in ER+ breast cancer

In looking for new ways to fight breast cancer, scientists from Duke-NUS Medical School have unmasked a surprising role of a protein generally associated with cancer growth. They have discovered that in estrogen receptor-positive (ER+) breast cancer, this protein acts as a tumor suppressor instead. ER+ breast cancer constitutes about 80 percent of all breast cancer diagnoses, yet nearly 50 percent of women diagnosed with it experience a relapse after initial treatment.

27 Aug 2024

Gut microbiota plays a critical role in rotavirus vaccine efficacy

Certain types of gut bacteria can hinder the efficacy of the rotavirus vaccine, according to researchers at the Institute for Biomedical Sciences at Georgia State University.

27 Aug 2024

New intranasal COVID-19 vaccine promises broad protection and accessibility

A next-generation COVID-19 mucosal vaccine is set to be a gamechanger not only when delivering the vaccine itself, but also for people who are needle-phobic.

27 Aug 2024

Exclusive breastfeeding aids postpartum weight loss

A KK Women's and Children's Hospital (KKH) study[1] on breastfeeding practices revealed that among the women who exclusively breastfed, those with high body mass index[2] (BMI) before pregnancy lost more weight than women with a healthy BMI pre-pregnancy.

27 Aug 2024

Should extremely preterm infants be given probiotics?

Researchers found that probiotics similarly impact the gut microbiome in extremely preterm infants as in very preterm infants, suggesting potential benefits for NEC prevention, but further research is needed.

26 Aug 2024

Renewed interest in psychedelics as potential addiction therapies

After years of being seen as dangerous "party drugs," psychedelic substances are receiving renewed attention as therapies for addiction -- but far more research is needed, according to a new special series of articles in the Journal of Studies on Alcohol and Drugs, published at Rutgers University.

26 Aug 2024

How diet shapes gut microbiota and affects brain function

Researchers discuss the diet-microbiota-gut-brain axis, which describes the role of both diet and gut microbiota composition on cognitive and emotional health.

26 Aug 2024

Widespread inhaler misuse in COPD patients: Need for training

Study found that 69% of hospitalized COPD patients misused inhalers, with 66% making critical errors, and 14% having insufficient Peak Inspiratory Flow (PIF), even after training.

25 Aug 2024

Telehealth mindfulness interventions significantly improve chronic pain outcomes for veterans

Scalable telehealth mindfulness-based interventions (MBIs) effectively improve pain-related function and biopsychosocial outcomes in veterans with chronic pain compared to standard care. The study confirms that low-cost, non-pharmacological treatments like MBIs can be accessible and beneficial via telehealth platforms.

25 Aug 2024

Study reveals metabolic switch crucial for memory T cell formation and cancer immunity

A Ludwig Cancer Research study has identified a metabolic switch in the immune system's T cells that is essential to the generation of memory T cells-;which confer lasting immunity to previously encountered pathogens-;and a T cell subtype found in tumors that drives anti-tumor responses during immunotherapy.

23 Aug 2024

Efficacy News and Research

Novel bottom-up approach in synthetic immunology opens a new frontier for disease treatment

New study shines light on the immune response to gonorrhea

Semaglutide shown to cut major adverse cardiovascular events in heart failure patients

Study identifies Gα13 as a key tumor suppressor in ER+ breast cancer

Gut microbiota plays a critical role in rotavirus vaccine efficacy

New intranasal COVID-19 vaccine promises broad protection and accessibility

Exclusive breastfeeding aids postpartum weight loss

Should extremely preterm infants be given probiotics?

Renewed interest in psychedelics as potential addiction therapies

How diet shapes gut microbiota and affects brain function

Widespread inhaler misuse in COPD patients: Need for training

Telehealth mindfulness interventions significantly improve chronic pain outcomes for veterans

Study reveals metabolic switch crucial for memory T cell formation and cancer immunity

New method determines optimal timing for cancer treatment based on circadian rhythm

Investigating the benefits of refined bamboo vinegar in anti-acne cosmetic formulations

Socioeconomic factors shape children's connection to nature more than urban or rural living

Universal flu vaccine candidate provides protection against severe infection in animal models

Advances in endoscopic treatment for inflammatory bowel disease complications

Innovative drug reduces inflammation in rats by inhibiting neutrophil activation

Cognitive behavioral therapy enhances the mental well-being and life quality of cancer patients

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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