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Detecting SARS-CoV-2 in 30 seconds with cheap and sensitive nanotubes

In a fascinating new medRxiv preprint paper, researchers from the University of Nevada, Reno demonstrate the power of cobalt-functionalized titanium dioxide nanotubes by selectively detecting the spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in less than 30 seconds.

10 Sep 2020

Scientists explain how SARS-CoV-2 attacks the brain

Now, a team of scientists at Yale University revealed the changes that happen in the brain caused by SARS-CoV-2, the virus that has caused over 27.86 million people and claimed over 903,000 lives.

10 Sep 2020

Computer-designed proteins can protect lab-grown human cells from SARS-CoV-2

Computer-designed small proteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19.

10 Sep 2020

Risk stratification tool for COVID-19 patients developed

Researchers have worked on the development of a protocol that could stratify COVID-19 patients based on a scoring system. This new study describing the scoring system for risk stratification is titled, “Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score,” and is published in the latest issue of the British Medical Journal.

9 Sep 2020

Pfizer, BioNTech COVID-19 vaccine candidate shows promise in preclinical study

Researchers in the United States and Germany have conducted a study demonstrating the preclinical efficacy of a new candidate vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

9 Sep 2020

Study sheds new light on function and regulation of APOBEC3B in adrenocortical carcinoma

The cover for issue 36 of Oncotarget features, "Knockdown of APOBEC3B is associated with a lower tumor growth in an adrenocortical carcinoma xenograft mouse model," by Gara, et al. which reported that the role of APOBEC3B in adrenocortical carcinoma and the mechanisms through which its expression is regulated in cancer are not fully understood.

9 Sep 2020

SARS-CoV-2 does not pose a food safety risk, health agency says

Now, a new report by the International Commission on Microbiological Specifications for Foods (ICMSF) highlights the link between SARS-CoV-2 infection and food safety. ICMSF is a global non-government organization that aims to provide information on food safety and human health.

8 Sep 2020

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), may reduce the protein's buildup and neurological decline associated with these disorders, suggests a pre-clinical study from researchers at Penn Medicine and Mayo Clinic.

8 Sep 2020

Antibody-mediated platelet death linked to COVID-19 severity

A new study by University of Tuebingen researchers shows the strong association between platelet apoptosis and the thrombotic manifestations that may underlie critical COVID-19 illness.

7 Sep 2020

Important research on SARS-CoV-2 proteins using proximity labeling

A team of Canadian scientists has recently discovered a wide-range interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and host proteins using proximity-dependent biotinylation approaches.

7 Sep 2020

Study: Small neutralizing antibody can block SARS-CoV-2 from entering human cells

Researchers at Karolinska Institutet in Sweden have identified a small neutralizing antibody, a so-called nanobody, that has the capacity to block SARS-CoV-2 from entering human cells.

4 Sep 2020

Brazilian state of Maranhão heading towards SARS-CoV-2 herd immunity, say researchers

Researchers at the Federal University of Maranhão, Brazil, have conducted a study suggesting that the state of Maranhão is well on its way to acquiring herd immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

2 Sep 2020

Promising new candidate 'virus-like particle' vaccine for COVID-19

Researchers in the UK and Taiwan have demonstrated the potential of a new candidate vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the virus responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

1 Sep 2020

Spike ferritin nanoparticles show potential as SARS-CoV-2 vaccine

Now, a new study published on the preprint server bioRxiv* in August 2020 reports the induction of neutralizing antibodies in mice by a single dose of a ferritin nanoparticle-based vaccine containing the spike protein.

1 Sep 2020

Scientists explain why SARS-CoV-2 targets multiple organs

Now, a team of researchers at LSU Health New Orleans’ Neuroscience Center of Excellence and School of Medicine has explained the gateway receptor for SARS-CoV-2 and how it leads to the emergence of many complications as it targets many parts of the body.

31 Aug 2020

Scientists solve structure of ORF8 coronavirus protein

Researchers at the University of California and the Lawrence Berkeley National Laboratory have made important discoveries about a protein found on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could lay the foundations for the development of new treatments.

31 Aug 2020

New lipid derivatives of Remdesivir have higher anti-coronavirus activity

In a fascinating new preprint paper published on bioRxiv* in August 2020, the researchers report “the synthesis and antiviral evaluation of three novel lipophilic prodrugs of RVn-monophosphate that are substantially more active than Remdesivir in cells infected with SARS-CoV-2.” These could be of immense use in treating COVID-19 patients early and helping to end transmission.

30 Aug 2020

Severe and fatal COVID-19 is rare in children

Now, a new study by researchers at the Universities of Edinburgh and Liverpool, Imperial College London, and the Royal Hospital for Children, Glasgow in the United Kingdom has shown that children and teenagers are less likely than adults to develop severe COVID-19 or die from the disease.

30 Aug 2020

New biomaterials from spider silk eliminate risk of infection and facilitate healing process

New biomaterials developed at the University of Bayreuth eliminate risk of infection and facilitate healing processes.

28 Aug 2020

Exploring the structure and dynamics of biological nanomachine

A small but important step towards a successful immune reaction is performed by an impressive nanomachine. Researchers use simulations to understand how it works.

28 Aug 2020