Electron Microscopy News and Research

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Research may lead to better treatment and vaccines for Ebola, COVID-19

In the midst of a global pandemic with COVID-19, it's hard to appreciate how lucky those outside of Africa have been to avoid the deadly Ebola virus disease.

21 Dec 2020

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

There is light at the end of the COVID-19 pandemic tunnel. Several vaccines against the SARS-CoV-2 virus that causes COVID-19 are now in clinical trials, with one -- developed by Pfizer/BioNTech -- already having been approved for emergency use in the United States.

18 Dec 2020

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

A new study describes the in vitro mechanism by which remdesivir kinetically inhibits the replication of the virus that causes COVID-19, SARS-CoV-2.

18 Dec 2020

Novel method reveals the synaptic basis for feature selectivity

A common analogy used to describe the brain is that it consists of tiny interconnected computers.

17 Dec 2020

Soft X-ray microscopy with record resolution of 7 nm

Researchers at Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), the Paul Scherrer Institute in Switzerland and other institutions in Paris, Hamburg and Basel, have succeeded in setting a new record in X-ray microscopy.

11 Dec 2020

Researchers identify new target that may lead to novel treatment for Alzheimer’s disease

Researchers at the Case Western Reserve University School of Medicine have identified a new target in development of Alzheimer's disease (AD) that could lead to therapies focused on treating the neurodegenerative condition early in its progression.

7 Dec 2020

Rice biochemist discovers hidden structure in essential metabolic machinery

In his first year of graduate school, Rice University biochemist Zachary Wright discovered something hidden inside a common piece of cellular machinery that's essential for all higher order life from yeast to humans.

5 Dec 2020

Study shows how minerals come together at molecular level to form bones, hard tissues

A new paper in Science Advances describes for the first time how minerals come together at the molecular level to form bones and other hard tissues, like teeth and enamel.

4 Dec 2020

Designed proteins assemble antibodies into modular nanocages

With cues from nature, designing functional molecules enables scientists to nanoengineer and customize for specific uses.

3 Dec 2020

Researchers use new imaging technique to produce digital reconstruction of eye tissues

A new study by scientists at the University of Southampton has made a breakthrough that could help the search for treatments against age related sight loss.

2 Dec 2020

Expansion microscopy allows imaging of cell membranes in super resolution

For the first time ever, expansion microscopy allows the imaging of even the finest details of cell membranes. This offers new insights into bacterial and viral infection processes.

2 Dec 2020

Researchers reveal how SARS-CoV-2 reaches the brain

Using post-mortem tissue samples, a team of researchers from Charité - Universitätsmedizin Berlin have studied the mechanisms by which the novel coronavirus can reach the brains of patients with COVID-19, and how the immune system responds to the virus once it does.

30 Nov 2020

Scientists show SARS-CoV-2's viral replication with 3D integrative imaging

A team of researchers at Heidelberg University in Germany have performed a detailed imaging analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to determine how the virus reprograms infected cells.

24 Nov 2020

Molecular action of tarantula toxin may hold clues to better control of chronic pain

Oversized, hairy tarantulas may be unsightly and venomous, but surprisingly their hunter toxin may hold answers to better control of chronic pain.

23 Nov 2020

Mildly symptomatic COVID-19 patients may be contagious for longer than previously thought

Researchers in Brazil have reported two cases of people with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding infectious virus for a significantly longer period than has previously been reported.

23 Nov 2020

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

A thought-provoking new study reports that the anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike antibodies elicited by natural infection may not be able to neutralize emerging strains that display deletion mutations in their genomic RNA.

23 Nov 2020

COVID-19 potentially has negative impacts on male fertility

A review recently published in the Journal of Medical Virology has discussed some of the effects that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – may have on male fertility.

22 Nov 2020

Genetic modification in ‘coat’ of fatal brain virus may allow it to escape antibodies

A genetic modification in the 'coat' of a brain infection-causing virus may allow it to escape antibodies, according to Penn State College of Medicine researchers.

20 Nov 2020

SARS-CoV-2 deactivation on surfaces in 30 seconds with a copper paste

In a recent bioRxiv preprint paper, a team of researchers shows the possibility of using copper, in a new conformation, for effectively killing microbes immediately.

18 Nov 2020

Optimizing SARS-COV-2 inactivation for COVID-19 research at lower biosafety levels

Researchers at Montana State University have validated and compared two methods for inactivating the causative agent of coronavirus disease 2019 (COVID-19) that would enable the virus to be studied at a lower biosafety level (BSL) than the one currently required.

18 Nov 2020

Electron Microscopy News and Research

Research may lead to better treatment and vaccines for Ebola, COVID-19

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

Novel method reveals the synaptic basis for feature selectivity

Soft X-ray microscopy with record resolution of 7 nm

Researchers identify new target that may lead to novel treatment for Alzheimer’s disease

Rice biochemist discovers hidden structure in essential metabolic machinery

Study shows how minerals come together at molecular level to form bones, hard tissues

Designed proteins assemble antibodies into modular nanocages

Researchers use new imaging technique to produce digital reconstruction of eye tissues

Expansion microscopy allows imaging of cell membranes in super resolution

Researchers reveal how SARS-CoV-2 reaches the brain

Scientists show SARS-CoV-2's viral replication with 3D integrative imaging

Molecular action of tarantula toxin may hold clues to better control of chronic pain

Mildly symptomatic COVID-19 patients may be contagious for longer than previously thought

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

COVID-19 potentially has negative impacts on male fertility

Genetic modification in ‘coat’ of fatal brain virus may allow it to escape antibodies

SARS-CoV-2 deactivation on surfaces in 30 seconds with a copper paste

Optimizing SARS-COV-2 inactivation for COVID-19 research at lower biosafety levels

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Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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