Electron Microscopy News and Research

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New insights into the molecular mechanism of protein degradation

Within the intricate molecular landscape inside of a cell, the orchestration of proteins demands precise control to avoid disease.

22 Sep 2023

Bacteriophage cocktail can effectively disrupt Klebsiella pneumoniae biofilms on medical equipment

Researchers investigated whether a cocktail of bacteriophages coding for the depolymerase polysaccharide could effectively disrupt Klebsiella pneumoniae biofilms.

18 Sep 2023

Researchers identify a rare cause of male infertility and discover a potential cure

Researchers investigated the genetic underpinning of asthenozoospermia, the leading cause of male fertility.

18 Sep 2023

Wireless molecular-electrical communications for tumor-cell-induced apoptosis

Researchers utilize electricity generated by wireless-induced redox interactions at bio-nanoantennae to cause apoptosis in cancerous cells.

18 Sep 2023

Research opens up new directions to develop drugs for stopping cytokine storms

Constant exposure of cells to stressing agents, such as pathogens, may disturb an organism's normal functioning. To fight stress, cells have developed several coping mechanisms, including the inflammatory response.

14 Sep 2023

Mount Sinai researchers identify the structure of a special red blood cell transporter

Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs.

8 Sep 2023

Cholesterol crystals linked to diabetic retinopathy

Advancements that could lead to earlier diagnosis and treatment for diabetic retinopathy, a common complication that affects the eyes, have been identified by a multi-department research team from Michigan State and other universities.

5 Sep 2023

Scientists discover new microglial population important for memory and learning

Following more than seven years of research, researchers at the University of Seville-IBiS (Institute of Biomedicine of Seville) have identified a new key cell type with a critical role in the developmental processes of memory and learning.

31 Aug 2023

Researchers unearth secrets of zinc transporter protein

A group of researchers has unearthed the secrets behind a tiny but crucial protein that shuttles zinc ions (Zn2+) within our bodies. The discovery offers a deeper understanding of how our cells maintain optimal health.

31 Aug 2023

Ion channel proteins can transiently rearrange into larger structures

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill Cornell Medicine.

30 Aug 2023

UC researchers study parasite that causes Chagas disease

Almost everything about insects called kissing bugs is revolting, from the insidious way they bite people's faces at night to drink their blood while they sleep to the way they spread disease through their poop.

23 Aug 2023

Researchers develop platform allowing mass-scale production of SARS-CoV-2 mRNA lipid nanoparticle vaccines

Researchers presented a scalable lipid nanoparticle production (SCALAR) platform to develop SARS-CoV-2 mRNA lipid nanoparticle vaccines.

15 Aug 2023

Unveiling α1-AR secrets: breakthrough structures and targeted drug design

Researchers explored the structural basis of agonist specificity of α1A-adrenergic receptors (α1-ARs).

14 Aug 2023

Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

The researchers demonstrated that glucokinase activation was effective in lowering blood glucose in mice with high-fat diet-induced obesity, while it potentially raised the risk of increasing hepatic lipid accumulation that triggered the PERK-UPR pathway.

11 Aug 2023

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Researchers used a multidisciplinary approach to investigate a nonstructural protein essential in SARS-CoV-2 replication.

10 Aug 2023

Mitochondrial protein structure activates cell's integrated stress response

Often referred to as the "powerhouses of the cell," mitochondria are well known for their role as energy suppliers, but these organelles are also critical for maintaining our overall health.

8 Aug 2023

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

B cells or B lymphocytes are an important part of the body's immune system. When healthy B cells are infected with the Epstein-Barr virus (EBV), they undergo growth transformation, a process that immortalizes B cells, leading to their uncontrolled proliferation.

7 Aug 2023

Cryo-EM structures and functions of potent bispecific antibodies against multiple Omicron sublineages

Researchers characterizes the structures and functions of potent bispecific antibodies against multiple Omicron subvariants using Cryo-EM.

3 Aug 2023

Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load

In a recent study, researchers working at Ohio State University in the United States of America (USA) developed an intranasal subunit vaccine.

2 Aug 2023

New study spotlights effective strategy against COVID-19 variants: the E7 monoclonal antibody

Researchers developed potent monoclonal antibodies from a severe acute respiratory syndrome coronavirus (SARS-CoV) survivor.

1 Aug 2023

Electron Microscopy News and Research

New insights into the molecular mechanism of protein degradation

Bacteriophage cocktail can effectively disrupt Klebsiella pneumoniae biofilms on medical equipment

Researchers identify a rare cause of male infertility and discover a potential cure

Wireless molecular-electrical communications for tumor-cell-induced apoptosis

Research opens up new directions to develop drugs for stopping cytokine storms

Mount Sinai researchers identify the structure of a special red blood cell transporter

Cholesterol crystals linked to diabetic retinopathy

Scientists discover new microglial population important for memory and learning

Researchers unearth secrets of zinc transporter protein

Ion channel proteins can transiently rearrange into larger structures

UC researchers study parasite that causes Chagas disease

Researchers develop platform allowing mass-scale production of SARS-CoV-2 mRNA lipid nanoparticle vaccines

Unveiling α1-AR secrets: breakthrough structures and targeted drug design

Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Mitochondrial protein structure activates cell's integrated stress response

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

Cryo-EM structures and functions of potent bispecific antibodies against multiple Omicron sublineages

Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load

New study spotlights effective strategy against COVID-19 variants: the E7 monoclonal antibody

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Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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