Embryonic development or embryogenesis is the process by which the embryo is formed and develops. It starts with the fertilization of the ovum, egg, which, after fertilization, is then called a zygote. The zygote undergoes rapid mitotic divisions, the formation of two exact genetic replicates of the original cell, with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of an embryo.
Scientists at Washington University School of Medicine in St. Louis appear to have solved a decades-long mystery regarding the precise biochemical pathway leading to a fatal genetic disorder in children that results in seizures, developmental regression and death, usually around age 3.
A team headed by Vincent Pasque at his Lab at KU Leuven alongside researchers from the Jean-Christophe Marine lab and the Edith Heard lab have made a significant step towards developing a treatment for Rett syndrome and other X chromosome linked disorders.
After working on stem cells for several years, scientists have now announced that they have found a way to synthesize structures that look like very primitive human embryos. While some hailed the discovery, others questioned the ethical basis of manufacturing synthetic humans.
New research from the University of Maryland and the National Institutes of Health reveals a new role for the enzyme telomerase.
An international collaboration led by a team at Oxford Brookes University has identified an important new gene which could open up new doors for research and developing new therapies.
Pluripotent cells can give rise to all cells of the body, a power that researchers are eager to control because it opens the door to regenerative medicine and organ culture for transplants.
Scientists at the German Center for Neurodegenerative Diseases have identified a group of proteins that help to regenerate damaged nerve cells. Their findings are reported in the journal Neuron.
The researchers led by Professor Raphael Stoll therefore expect their results to form a basis for future therapeutic strategies to combat cancers caused by HMGA1a.
A new study coordinated by the Research Group in Developmental Biology at UPF shows that during the embryonic development of the brain, the cells that are between adjacent segments detect the mechanical forces generated during morphogenesis to regulate the balance between progenitor stem cells and differentiated neurons.
Dolutegravir is a preferred medication for treating HIV infection, but it recently has been linked to a 6- to 9-fold increase in the risk for neural tube defects among babies born to mothers receiving the drug during early gestation.
An epigenetic change, a form of DNA control, that deactivates some genes linked to cancer late in human development has been conserved for more than 400 million years, new research led by the Garvan Institute of Medical Research suggests.
A team of scientists led by Dr Enrique Lara Pezzi at the Centro Nacional de Investigaciones Cardiovasculares has identified the RNA-binding protein SRSF3 as an essential factor for proper heart contraction and survival.
In Belgium, there are 70,000 new adult cases of cancer every year, compared to 350 in children. Owing to lack of interest from pharmaceutical groups, treatments for pediatric cancers are developing much less rapidly than those for adults.
Scientists from the University of Bath are challenging the claims of two high profile papers from 2018 which reported that in the mouse, RNA has to be added to sperm for them to be fully fertile.
From a biological standpoint, the earliest stages of life are the most mysterious. A developing human embryo undergoes a flurry of rapid changes, and these changes are exceedingly difficult to study because they transpire within the confines of a womb.
A 12-week consultation has been launched to discuss whether folic acid should be added to flour in the UK.
The study shows that the presence of Ochratoxin A affects survival and decreases the proliferation of human cells in the embryonic phase
Professor of Ghent University and Lead Researcher at the Institute of Biology and Biomedicine of the Lobachevsky University Dmitri Krysko together with scientists from Germany, Professor Marcus Conrad and Professor Jose Pedro Friedmann Angeli recently published an article in the journal Nature Reviews Cancer, one of the highest-rated journals that occupies the 2nd line in the oncology section among 223 journals in this category and has an impact factor of 42.78 according to WoS data.
A close look at the rapidly developing zebrafish embryo is helping neuroscientists better understand the potential underpinnings of brain disorders, including autism and schizophrenia.
The architecture of the DNA-protein complexes that make up the genome in each cell nucleus regulates the course of early embryonic development.