Embryonic development or embryogenesis is the process by which the embryo is formed and develops. It starts with the fertilization of the ovum, egg, which, after fertilization, is then called a zygote. The zygote undergoes rapid mitotic divisions, the formation of two exact genetic replicates of the original cell, with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of an embryo.
Researchers have found that there a numerous transposons or “jumping genes” within the genetic code that is responsible for development of the embryo and its growth. These were earlier thought to be junk or useless parts of the genome.
Researchers have uncovered a trigger for an immune-related cell death pathway called necroptosis. The discovery could be used to develop new treatments for cancer and immune disorders.
In vitro fertilization affects the regulatory region of genes essential for placental and embryonic growth, as well as the birth weight.
Researchers have discovered that the structural protein SMCHD1 is required to prevent genes from both X chromosomes being expressed in female mammals.
Fuyuhiko Tamanoi of Kyoto University's Institute for Integrated Cell-Material Sciences and colleagues in the US succeeded in establishing a versatile, powerful and convenient model to analyze human cancer.
It all began with one young patient; a 7-year old boy who was born without a thymus, an important organ of the immune system, and without functional immune cells. The boy also presented with cardiac and skeletal defects, dysmorphic craniofacial features and some signs of autistic behaviors.
Dr. Atilgan Yilmaz and his team have developed a method by which they can produce haploid human embryonic stem cells from oocytes. They combined this technique with CRISPR-Cas9 to generate an atlas of the genome, containing the functions of over 18,000 genes.
Thanks to advances in the development of anti-retroviral therapy (ART), patients with HIV are living longer than ever before. And yet, even in patients on very effective, long-term ART, HIV persists, requiring patients to take antiviral medication life-long.
Publication in Nature Cell Biology: researchers at the Université libre de Bruxelles, ULB define for the first time the mechanisms responsible for the mammary gland development.
One of the most frequent causes of drug-resistant epilepsy, considered a difficult disease to control, is a brain malformation known as focal cortical dysplasia.
Scientists exploring how to tame random gene fluctuations as the embryos that become our bodies start to form have identified a control switch in the vertebrate segmentation clock of developing zebrafish.
A team of biologists has determined how transcription factors (TFs), which guide gene regulation, function differently in embryonic development.
A new technique that uses tiny elastic balls filled with fluorescent nanoparticles aims to expand the understanding of the mechanical forces that exist between cells, researchers report.
A Brazilian study published April 26 in the journal Cancer Research shows for the first time in vivo that Zika virus can be used as a tool to treat aggressive human central nervous system (CNS) tumors.
A new study in the journal Nature Cell Biology has uncovered information about a key stage that human embryonic cells must pass through just before an embryo implants. The research, led by UCLA biologist Amander Clark, could help explain certain causes of infertility and spontaneous miscarriage.
Using a technology that provides a 'high-resolution view' of the status of individual cells, a team of researchers has gained new insights into the embryonic development of the mouse heart.
Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
Every biology textbook states that cells are life's building blocks. But researchers are only now beginning to understand their diversity. Technologies such as RNA sequencing are revealing which genes are expressed in each individual cell.
UCLA researchers used fluorescent colored proteins to trace how cardiomyocytes -- cells in heart muscle that enable it to pump blood -- are produced in mouse embryos. The findings could eventually lead to methods for regenerating heart tissue in human adults.
Australian biomedical engineers have successfully produced a 3D material that mimics nature to transform cells into muscle.