Embryonic development or embryogenesis is the process by which the embryo is formed and develops. It starts with the fertilization of the ovum, egg, which, after fertilization, is then called a zygote. The zygote undergoes rapid mitotic divisions, the formation of two exact genetic replicates of the original cell, with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of an embryo.
An epigenetic change, a form of DNA control, that deactivates some genes linked to cancer late in human development has been conserved for more than 400 million years, new research led by the Garvan Institute of Medical Research suggests.
A team of scientists led by Dr Enrique Lara Pezzi at the Centro Nacional de Investigaciones Cardiovasculares has identified the RNA-binding protein SRSF3 as an essential factor for proper heart contraction and survival.
In Belgium, there are 70,000 new adult cases of cancer every year, compared to 350 in children. Owing to lack of interest from pharmaceutical groups, treatments for pediatric cancers are developing much less rapidly than those for adults.
Scientists from the University of Bath are challenging the claims of two high profile papers from 2018 which reported that in the mouse, RNA has to be added to sperm for them to be fully fertile.
From a biological standpoint, the earliest stages of life are the most mysterious. A developing human embryo undergoes a flurry of rapid changes, and these changes are exceedingly difficult to study because they transpire within the confines of a womb.
A 12-week consultation has been launched to discuss whether folic acid should be added to flour in the UK.
The study shows that the presence of Ochratoxin A affects survival and decreases the proliferation of human cells in the embryonic phase
Professor of Ghent University and Lead Researcher at the Institute of Biology and Biomedicine of the Lobachevsky University Dmitri Krysko together with scientists from Germany, Professor Marcus Conrad and Professor Jose Pedro Friedmann Angeli recently published an article in the journal Nature Reviews Cancer, one of the highest-rated journals that occupies the 2nd line in the oncology section among 223 journals in this category and has an impact factor of 42.78 according to WoS data.
A close look at the rapidly developing zebrafish embryo is helping neuroscientists better understand the potential underpinnings of brain disorders, including autism and schizophrenia.
The architecture of the DNA-protein complexes that make up the genome in each cell nucleus regulates the course of early embryonic development.
Genetic variation in heart valve cells of the developing fetus create the blueprint for the later development of mitral valve prolapse, according to the cover story of today's Science Translational Medicine.
Not all cells are destined for greatness. Deemed unfit to serve in the body, some are killed off during early development through a process called cell competition. This phenomenon has previously been documented in flies and is now turning out to occur in mammals as well.
Medications have to be safe for mothers-to-be and for their unborn children. Before the authorities will approve a new drug, it must be tested in animal trials on pregnant rodents and, as a rule, pregnant rabbits.
How do bones heal, and how could they heal better? The answer to these questions may lie in a newly discovered population of "messenger" cells, according to a recent USC Stem Cell study published in the journal eLife.
All the surface of the human body is represented in the cerebral cortex in a transversal band localized at the external part of the cerebral hemispheres: the somatosensory cortex.
Induced pluripotent stem cells can turn into any type of cell in the body or remain in their original form. In the current edition of Molecular Cell, scientists from the Helmholtz Zentrum München describe how cells “decide” which of these two directions to take.
Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells.
The human genome is fascinating. Once predicted to contain about a hundred thousand protein-coding genes, it now seems that the number is closer to twenty thousand, and maybe less.
More than a decade ago, radiation oncologists noticed a nifty phenomenon: Sometimes radiation used locally against a tumor could excite the immune system to attack cancer systemically throughout the body.
Ramón Muñoz-Chápuli and Rita Carmona, researchers of the UMA Department of Animal Biology, have identified a new molecular mechanism involved in pancreas repair.