Embryonic Development News and Research

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Embryonic development or embryogenesis is the process by which the embryo is formed and develops. It starts with the fertilization of the ovum, egg, which, after fertilization, is then called a zygote. The zygote undergoes rapid mitotic divisions, the formation of two exact genetic replicates of the original cell, with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of an embryo.

Regulation of the retinoic acid gradient in zebrafish embryos

Human embryos that get too much or too little retinoic acid, a derivative of Vitamin A, can develop into babies with birth defects.

21 Nov 2007

Discovery of 300 previously unidentified human genes

Using supercomputers to compare portions of the human genome with those of other mammals, researchers at Cornell have discovered some 300 previously unidentified human genes, and found extensions of several hundred genes already known.

21 Nov 2007

First chemical evidence of a sperm recognition system in the oviducts of pigs

Adding another layer of competition to the mating game, scientists are reporting possible biochemical proof that the reproductive system of female mammals can "sense" the presence of sperm and react to it by changing the uterine environment.

19 Nov 2007

Human embryonic stem cells derived from preimplantation genetically diagnosed embryos

A human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis (PGD) to carry the mutation for fragile X syndrome has provided an unprecedented view of early events associated with this disease.

15 Nov 2007

The role of growth factor in vertebrae formation

The Stowers Institute's Pourquié Lab has demonstrated the role of fibroblast growth factor (FGF) in the embryonic process of somitogenesis, an event required for vertebrae formation, in a paper posted to the Web site of the journal Development.

31 Oct 2007

New egg-specific gene, JY-1 offers clues to infertility

A newly identified gene that controls embryo development in cows may someday offer clues into the cause of infertility in women.

29 Oct 2007

Heparanase shows potential as cancer drug

Laboratory experiments have previously shown that cancer cells overproduce an enzyme, heparanase, which splits the body's own polysaccharide heparan sulfate into shorter fragments.

22 Oct 2007

T-cell exhaustion

A new study of immune cells battling a chronic viral infection shows that the cells, called T cells, become exhausted by the fight in specific ways, undergoing profound changes that make them progressively less effective over time.

19 Oct 2007

Important insights into blood vessel formation

Researchers have identified a molecular pathway that plays a critical role in the growth of blood vessels.

15 Oct 2007

Scientists answer century-old developmental question

Embryologists at UCL (University College London) have helped solve an evolutionary riddle that has been puzzling scientists for over a century.

11 Oct 2007

In biology, polarization is a good thing

Using a molecular cellular compass, individual cells in complex organisms know which way is up or down, in epithelial cells known as apical-basal polarity.

9 Oct 2007

Sir Martin Evans wins Nobel prize for stem cell research

Medical Research Council funded scientist Sir Martin Evans, has been awarded the Nobel Prize in Physiology or Medicine for 2007 alongside Mario R. Capecchi and Oliver Smithies for their discoveries of "principles for introducing specific gene modifications in mice by the use of embryonic stem cells".

9 Oct 2007

Low maternal cholesterol levels may lead to adverse birth outcomes

Pregnant women who have very low cholesterol may face a greater risk of delivering their babies prematurely than women with more moderate cholesterol levels, a team led by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), reported today.

2 Oct 2007

Scientists study folding of the brain's cortex

Engineers at Washington University in St. Louis are finding common ground between the shaping of the brain and the heart during embryonic development.

2 Oct 2007

European project to look at the wiring of the brain during growth

One of the great questions of neurobiology, how the brain is built up during embryonic development, could be resolved by a young French scientist in an award winning project organised by the European Science Foundation (ESF) and the European Heads of Research Councils (EuroHORCS).

24 Sep 2007

JAK genes and cancer

Cancer-causing genes can work in more powerful and sneaky ways than have been realized.

18 Sep 2007

N-cofilin molecule protects from neuronal disorders

Many neuronal disorders, including epilepsy, schizophrenia and lissencephaly – a form of mental retardation - result from abnormal migration of nerve cells during the development of the brain.

17 Sep 2007

Fetal neurons play role in adult brain

Subplate neurons - once thought to die after directing the wiring of the cerebral cortex or gray matter - remain in the white matter of the adult brain in small numbers and maintain activity, communicating with other neurons in the brain said researchers from Baylor College of Medicine and the University of Alabama at Birmingham in a report that appears in today's issue of the Journal of Neuroscience

12 Sep 2007

Schizophrenia-linked gene keeps new adult brain cells under control

The study reveals that the gene, known as Disrupted-In-Schizophrenia 1 (DISC1), directs the incorporation of new neurons into the adult brain and keeps the process under control. The gene's newly discovered roles might help to explain why schizophrenia's symptoms generally arise in adolescence or early adulthood, the researchers suggested.

10 Sep 2007

Scientists speed healing of bone damage

Blocking a naturally occurring inhibitor of bone formation accelerates healing of skull defects in mice, say researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital. The finding advances the understanding of how the skeleton develops and opens new therapeutic avenues for many of the disorders that are expected to afflict aging baby boomers.

5 Sep 2007