Encephalopathy News and Research

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Penn Medicine researchers identify new therapeutic target for Alzheimer's disease

A gene encoding a protein linked to tau production-;tripartite motif protein 11 (TRIM11)-;was found to suppress deterioration in small animal models of neurodegenerative diseases similar to Alzheimer's disease (AD), while improving cognitive and motor abilities, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

27 Jul 2023

Is repetitive heading of the ball during a professional soccer career associated with an increased risk of cognitive impairment?

In a recent study, a group of researchers investigated if heading frequency is associated with cognitive impairment in retired soccer players.

20 Jul 2023

New method improves prediction of liver disease progression

A research team from the Department of Medicine III at MedUni Vienna and University Hospital Vienna has conducted a large-scale study showing the important value of repeated liver assessments by a novel method that can significantly improve risk assessment in patients with chronic liver disease.

17 Jul 2023

PET scan not effective in diagnosing chronic traumatic encephalopathy in former NFL players, study finds

A new study showed that positron emission tomography (PET) with the radiotracer (18F)-Flortaucipir (FTP) to detect hyperphosphorylated Tau (p-tau) may not be appropriate for diagnosing chronic traumatic encephalopathy (CTE) neuropathologic changes in former professional American-style football players.

5 Jul 2023

New study reveals alarming cognitive impairments in long COVID patients

Persistent COVID-19 symptoms can lead to cognitive deficits in recovered patients. This systematic review highlights the need for further research and interventions to address long-term cognitive impairments.

28 Jun 2023

Football players at risk for CTE based on cumulative force of head hits, study shows

For years, researchers studying chronic traumatic encephalopathy, or CTE, believed the primary cause of it was repetitive hits to the head, whether or not those hits caused concussions.

23 Jun 2023

Research finds link between biomarkers in vitreous humor of the eye and Alzheimer's disease

New research from Boston Medical Center found a significant correlation between biomarkers in the vitreous humor of the eye and pathologically confirmed cases of Alzheimer's disease (AD) and Chronic Traumatic Encephalopathy (CTE) in post-mortem brain and eye tissue.

16 Jun 2023

Diet's powerful impact: How gut microbes shape health and battle disease

Research paper discusses the relationship between gut microbiota, diet, and health. It highlights the importance of dietary complex carbohydrates and the potential negative effects of diets high in animal protein and fat on the composition of the microbiota and their metabolic outputs.

4 May 2023

Therapeutic hypothermia for treating neonatal encephalopathy ineffective for some newborns

Therapeutic hypothermia, the only evidence-based treatment for newborns born with neonatal encephalopathy (NE) at or after 36 weeks, is not effective for reducing death or moderate/severe disability in newborns born between 33 and 35 weeks, according to a new study.

28 Apr 2023

Study examines whether alcohol-associated burn injuries impair cognitive function

The relationship between alcohol use and burn injuries is a negative one in multiple ways. Not only are about 50% of adults who sustain burn injuries intoxicated at the time of injury, suggesting that alcohol use may have contributed to the incident, but alcohol use among burn-injured patients is associated with more severe complications, delayed recovery, and increased morbidity and mortality.

10 Apr 2023

Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

In a recent study published in the Journal of the Alzheimer's Association (AA), researchers examined the effects of a low-carbohydrate-modified Mediterranean ketogenic diet (MMKD) on the gut microbiome and metabolome of patients at risk for Alzheimer's disease (AD).

9 Apr 2023

Case study shows how COVID-19 breached the placenta and caused brain damage in the baby

Researchers at UHealth-;the University of Miami Health System and the University of Miami Miller School of Medicine have shown that, in two cases, COVID-19 infection breached the placenta and caused brain damage in the newborn.

6 Apr 2023

Computational approach used to understand the mechanisms of protein folding in tauopathies

A team at UT Southwestern has developed a computational approach to uncover mechanisms of protein misfolding linked to neurodegenerative diseases.

27 Mar 2023

Playing tackle football at an early age increases risk for brain decline later

The degenerative brain disease known as CTE, or chronic traumatic encephalopathy, has become a specter haunting football.

20 Mar 2023

How does the gut microbiome affect muscle strength?

Researchers use fecal microbiome transplantation in mouse models to examine the role of gut microbiota in determining muscle strength.

14 Mar 2023

An overview of COVID-19-associated neurological complications in children

Researchers review current literature to understand the association between COVID-19, neuroimaging, and neurological symptoms in children.

14 Mar 2023

Active disease process in early CTE differs substantially from late-stage disease

Millions of people, including athletes who play contact sports, members of the military and victims of domestic violence, are exposed to repetitive head impacts (RHI), which is the primary risk factor for developing chronic traumatic encephalopathy (CTE).

13 Mar 2023