Endometrial Cancer News and Research

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Insights into why midlife women gain weight

Weight gain is a common complaint of midlife women, with more than two-thirds of midlife US women being over the ideal weight threshold. Aging-related metabolic changes promote weight gain in both sexes, but women face additional challenges because of menopause.

12 Oct 2022

What are the effects of heavy metals on the risk of endometriosis in reproductive-age women?

The current study focuses on lead, arsenic, cadmium, and mercury, all of which have been linked to the disordered functioning of the human reproductive system.

26 Sep 2022

HSD3B1 gene holds clues for predicting and treating endometrial cancer

The HSD3B1 gene could hold clues for predicting and treating endometrial cancer, according to a novel finding from the Cleveland Clinic's Lerner Research Institute.

13 Sep 2022

Conceptual framework to examine the patterns of copy number alterations in human cancer

A new study published in Nature presented a conceptual framework to examine the patterns of copy number alterations in human cancer.

17 Jun 2022

Weight loss with bariatric surgery associated with lower risk of cancer and cancer-related mortality

A Cleveland Clinic study shows that among adults with obesity, weight loss achieved with bariatric surgery was associated with a 32% lower risk of developing cancer and a 48% lower risk of cancer-related death compared with adults who did not have the surgery.

3 Jun 2022

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Investigators from Rutgers Cancer Institute of New Jersey, New Jersey's only National Cancer Institute- Designated Comprehensive Cancer Center, led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens including microsatellite-stable and unstable (MSI) tumors.

19 May 2022

Lifelong excess weight almost doubles the risk of developing womb cancer, shows study

New research shows that lifelong excess weight almost doubles a woman's risk of developing womb cancer, according to a Cancer Research UK-funded study published today in BMC Medicine.

19 Apr 2022

Combination therapy shows promising results in patients with recurrent ER-positive endometrial cancer

A combination therapy that targets cancer cells from within and without caused tumors to shrink or stabilize in 75% of patients with recurrent or persistent estrogen receptor- (ER-) positive endometrial cancer, results from a recent clinical trial show.

19 Mar 2022

Anti-Müllerian hormone plays an active role in polycystic ovary syndrome

High levels of anti-Mullerian hormone (AMH) have traditionally been thought of as merely a passive byproduct of polycystic ovary syndrome (PCOS), but a new preclinical study by Weill Cornell Medicine researchers suggests that the hormone plays an active role in the disorder and may contribute to problems with ovulation and fertility.

10 Mar 2022

New fluorescent label provides a clearer picture of how DNA architecture is disrupted in cancer cells

Researchers have developed a new fluorescent label that gives a clearer picture of how DNA architecture is disrupted in cancer cells. The findings could improve cancer diagnoses for patients and classification of future cancer risk.

4 Mar 2022

Study uses Promega LMR MSI Analysis System to detect microsatellite instability in multiple cancers

Researchers from Johns Hopkins University have shown that a new panel of long mononucleotide repeats might offer advantages over traditional microsatellite instability detection methods in certain types of solid tumors.

7 Feb 2022

Study identifies high-priority genes associated with uterine cancer that could be potential drug targets

No single gene causes uterine cancer, the fourth most common cancer among women, which is on the rise in the U.S.

28 Jan 2022

Long-excluded uterine cancer patients are step closer to 9/11 benefits

Tammy Kaminski can still recall the taste of benzene, a carcinogenic byproduct of burning jet fuel. For nine months after the 9/11 attacks, she volunteered for eight hours every Saturday at St. Paul's Chapel, just around the corner from ground zero in New York City.

13 Jan 2022

Moffitt experts provide insight on the role of B cell immunity in endometrial cancer

Endometrial cancer is the most common cancer of the female reproductive system. Patients who have active immune responses against cancer cells tend to have better outcomes, but much of what is known focuses on only one type of immune cell called T cells.

13 Jan 2022

Mapping proteo-genomic connections between different human diseases

Hundreds of connections between different human diseases have been uncovered through their shared origin in our genome by an international research team led by scientists from the Medical Research Council Epidemiology Unit at the University of Cambridge, challenging the categorization of diseases by organ, symptoms, or clinical specialty.

15 Oct 2021

Contraceptive pill can reduce the risk of type 2 diabetes in women with PCOS, study reveals

A study led by the University of Birmingham has revealed for the first time that the contraceptive pill can reduce the risk of type 2 diabetes by over a quarter in women with polycystic ovary syndrome (PCOS).

15 Oct 2021

Promising data from early clinical trials of new anticancer therapies presented at ESMO Congress 2021

Data from early clinical trials presented at the ESMO Congress 2021 suggest that new anticancer treatments are on the horizon, with a clear emphasis on precision medicine.

24 Sep 2021

Low BMI levels can increase risk of endometrial cancer in obese Asian women

The link between obesity and the risk of endometrial cancer has been well documented. A new study, however, shows that an even lower body mass index (BMI) than previously thought can signal an increased risk in Asian women with postmenopausal bleeding. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).

30 Jun 2021

Survey shows racial and ethnic differences in use of personal care products

A large survey of women in California shows significant racial and ethnic differences in the types of personal care products women use on a daily basis.

19 May 2021

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

Today, the U.S. Food and Drug Administration granted accelerated approval to Jemperli (dostarlimab) for treating patients with recurrent or advanced endometrial cancer that has progressed on or following prior treatment with a platinum-containing chemotherapy and whose cancers have a specific genetic feature known as dMMR (which contain abnormalities that affect the proper repair of DNA inside the cell), as determined by an FDA-approved test.

22 Apr 2021