Endoplasmic reticulum (ER) News and Research

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Study proves the co-pay connection in chronic disease

As 2008 begins, millions of Americans are having to dig deeper into their own pockets every time they refill a prescription or see a doctor.

9 Jan 2008

Minorities less likely to receive pain-relieving opioid drugs in ER

Blacks and Hispanics who go to hospital emergency departments in pain are significantly less likely than whites to get pain-relieving opioid drugs, according to a new study funded by the U.S. Department of Health and Human Services.

7 Jan 2008

Where vets served affects frequency of ER visits but not hospital stays

Five years post-conflict, individuals who served in the 1990-1991 Persian Gulf War were 25 percent more likely to visit an emergency department than veterans of the same era who were not deployed, but were no more likely to have a hospital stay or an outpatient visit, according to a study appearing in the December 2007 issue of the American Journal of Public Health.

18 Dec 2007

Survival shortened when estrogen or progesterone receptor negative breast cancer spreads to the brain

Two studies from Mayo Clinic's site in Jacksonville, Fla., of women whose breast cancer spread to their brain, have found that women whose tumors do not have estrogen or progesterone receptors have the worst overall outcomes.

17 Dec 2007

Tumors less than 1 centimeter in size can be aggressive and may require maximum therapy

Breast tumors that are 1 centimeter in size or smaller - no more than 0.4 inch in length - can still be very aggressive and may require more intensive therapy than is routinely offered today, say researchers at Mayo Clinic in Jacksonville, Fla.

17 Dec 2007

New schizophrenia treatment

Schizophrenia is one of the most debilitating of the major psychiatric disorders, and is also one of the most difficult to treat.

14 Dec 2007

Venlafaxine extended-release effective for patients with major depression

Major depressive disorder (MDD) is the most common major mental illness, afflicting almost one in five individuals.

13 Dec 2007

Electronic patient tracking technologies versus manual whiteboards

Proper design of computational tools is critical if they are to be used with success in patient-care settings, particularly in hospital emergency rooms, a field study conducted by researchers at the University at Buffalo and other institutions recently revealed.

27 Nov 2007

Melatonin could actually be hurting you at night!

What do you do when a naturally occurring hormone in your body turns against you? What do you do when that same hormone - melatonin - is a popular supplement you take to help you sleep?

16 Nov 2007

Pre-malignant mammary lesions in dogs and humans display many of the same characteristics

...a discovery that could lead to better understanding of breast cancer progression and prevention for people and pets, said a Purdue University scientist from the School of Veterinary Medicine.

16 Nov 2007

Two proteins may be survival markers in some breast cancers

New research suggests that the presence or absence of two proteins may be important markers for long-term survival in some breast-cancer patients.

13 Nov 2007

Osteopontin-c is a good biomarker of breast cancer.

Researchers have identified a molecule that may be more accurate than existing biological signposts used to predict which breast cancers will develop into advanced forms of the disease.

6 Nov 2007

Fabre Kramer Pharmaceuticals receives FDA decision on Gepirone ER for major depressive disorder

Fabre-Kramer Pharmaceuticals Inc. (FKP) and GlaxoSmithKline announced today that the U.S. Food and Drug Administration (FDA) has issued a not approvable letter for the new drug application for gepirone extended- release (ER) tablets, submitted for the treatment of adults with major depressive disorder.

5 Nov 2007

New guideline recommends when to use CT scans in ER for seizures

A guideline developed by the American Academy of Neurology recommends immediate brain CT scans to screen certain emergency room patients with seizures.

29 Oct 2007

Attenuation of NASH by stimulation of free fatty acid metabolism

Medically-complicated obesity is a societal problem that needs to be solved. Liver disease, specifically non-alcoholic steatohepatitis or NASH, is just one of the many complications of increased body weight.

28 Oct 2007

Mylan settles Paroxetine Hydrochloride patent license with GlaxoSmithKline

Mylan Inc. has announced that it and its subsidiary Mylan Pharmaceuticals Inc. have entered into a patent license and settlement agreement with GlaxoSmithKline (GSK) relating to Paroxetine Hydrochloride (HCl) Extended-release (ER) Tablets, the generic version of GSK's Paxil CR.

24 Oct 2007

Legionnaire's bacterial proteins work together to survive

Proteins within the bacteria that cause Legionnaire's disease can kidnap their own molecular "coffin" and carry it to a safe place within the cell, ensuring their survival, Yale School of Medicine researchers report in Nature Wednesday.

24 Oct 2007

Molecular basis of the cyanide polymorphism

That clover necklace you make for your child could well be a ring of poison.

2 Oct 2007

Botched production of insulin molecule may lead to diabetes

Picture a pretzel factory production line, with conveyer belts carrying the dough, formed into unbaked pretzels, down to the oven to be cooked.

2 Oct 2007

Lean manufacturing principles boost efficiency at rural hospital

The emergency department at Meadows Regional Medical Center in rural Vidalia, Ga., has achieved what would make most hospitals across the nation envious: a 44 percent reduction in average length of stay per patient, a 10 percent boost in patients served and a 92 percent patient satisfaction rate.

26 Sep 2007