Endothelial cell News and Research

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Older corneas suitable for transplantation

The age pool of corneas for transplant should be expanded to include donors up to 75 years of age, based on findings from a study funded by the National Eye Institute (NEI), one of the National Institutes of Health (NIH).

2 Apr 2008

The mysterious link between summer birthdates and myopia

Do corneas from older donors meet quality standards for transplant surgery? These are among the topics explored in the April 2008 issue of Ophthalmology, the journal of the American Academy of Ophthalmology.

2 Apr 2008

Stem cells from hair follicles may help 'grow' new blood vessels

For a rich source of stem cells to be engineered into new blood vessels or skin tissue, clinicians may one day look no further than the hair on their patients' heads, according to new research published earlier this month by University at Buffalo engineers.

31 Mar 2008

What change does prokineticin 2/Bv8 have in human hepatocellular carcinoma?

Liver hepatocarcinoma is a highly vascularized cancer, and more and more research is focused on the molecules controlling angiogenesis.

19 Mar 2008

Toddlers affected most by secondhand smoke exposure at home

Secondhand smoke in the home appears to induce markers for heart disease as early as the toddler years, researchers reported at the American Heart Association's 48th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.

14 Mar 2008

Damaged veins heal faster with heparin treatment, laboratory study finds

A commonly used medication that prevents blood clots from forming may also prevent existing clots from damaging delicate vein walls and may accelerate healing in a clot-damaged area of vein wall, according to new research from the University of Michigan Cardiovascular Center.

14 Mar 2008

Study aims to improve treatment for children born with heart defects

Trying to understand and stop the collateral lung damage that can occur in babies with congenital heart disease is the focus of a new study.

11 Mar 2008

Discovery of potential drug targets for sepsis

"We have identified a key connection of signaling pathways in the cascade of events leading to sepsis. This defines a crucial point where the immune system spirals out of control to cause severe sepsis and where there is an opportunity for therapeutic intervention," says Scripps Research Professor Wolfram Ruf, who led the research with his postdoctoral fellow Frank Niessen.

28 Feb 2008

Study identifies another strategy for normalizing tumor blood supply

Manipulating levels of nitric oxide (NO), a gas involved in many biological processes, may improve the disorganized network of blood vessels supplying tumors, potentially improving the effectiveness of radiation and chemotherapy.

21 Feb 2008

Tumor blood vessels can develop from precancerous stem cells

Tumors require a blood supply to grow, but how they acquire their network of blood vessels is poorly understood.

20 Feb 2008

Transplanted cells can cure hemophilia

Scientists at the Albert Einstein College of Medicine of Yeshiva University have shown for the first time that transplanted cells can cure hemophilia A (the most common form of the disease) in an animal model.

18 Feb 2008

Brain molecule from endothelial cells may be a new target for treatment of multiple sclerosis

In the February issue of Nature Immunology, the team provides fresh answers concerning the role of novel adhesion molecules in the pathogenesis of MS, a chronic autoimmune disease of the nervous system that affects approximately 55,000 young adults in Canada.

23 Jan 2008

New magnetic method of delivering cells and genes to repair injured or diseased organs

Scientists have used magnetic fields and tiny iron-bearing particles to drive healthy cells to targeted sites in blood vessels.

8 Jan 2008

Hardening of the arteries - mutant gene identified as culprit

A genetic mutation expands lesions in the aorta and promotes coronary atherosclerosis, more commonly known as hardening of the arteries, according to a study by Yale School of Medicine in Cell Metabolism.

20 Dec 2007

Guideline for management of postmeal glucose

Christmas time is full of food when most of us simply have to worry about our expanding waist lines but new research led by the University of Warwick’s Medical School says that people with diabetes need to pay attention to the dangers of a neglected post meal peak in blood glucose.

10 Dec 2007

Lymphatic vessel and lymph node function are restored with growth factor treatment

The frequent spread of certain cancers to lymph nodes often necessitates surgery or radiation therapy that damages the lymphatic system and can cause lymphedema, a condition of localized fluid retention that often increases susceptibility to infections.

4 Dec 2007

New study finds blood-spinal cord barrier compromised in mice with ALS

The blood-spinal cord barrier is functionally impaired in areas of motor neuron damage in mice modeling amyotrophic lateral sclerosis (ALS), report researchers at the University of South Florida Center for Aging and Brain Repair.

21 Nov 2007

New device for screening potential new drug compounds

A new device invented by researchers at the University of Virginia could save pharmaceutical companies significant time and money in screening potential new drug compounds.

19 Nov 2007

Improved surgery technique for endothelial disease of the cornea

In a research presentation today at the American Academy of Ophthalmology's Annual Meeting, Massimo Busin, MD, department head and professor of ophthalmology at the Villa Serena Hospital, Forli, Italy, described a technique that significantly improved results in patients being treated for endothelial disease of the cornea, the transparent covering of the front of the eye that provides much of its optical power.

13 Nov 2007