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Clinical metagenomics, a faster approach to identify secondary infections in hospitalized COVID-19 patients

Scientists have demonstrated that clinical metagenomic detection of microbial communities can improve the management of infections in COVID-19 patients.

4 Dec 2020

New combination therapy may help fight antimicrobial resistance

An inexpensive, FDA-approved drug -- cholestyramine -- taken in conjunction with an antibiotic prevents the antibiotic from driving antimicrobial resistance, according to new research by scientists at Penn State and the University of Michigan. The team's findings appear today (Dec. 1) in the journal eLife.

2 Dec 2020

Researchers develop new method to customize lysins for targeting unwanted bacteria

Researchers from the Antimicrobial Resistance Interdisciplinary Research Group at Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have developed a method to produce customizable engineered lysins that can be used to selectively kill bacteria of interest while leaving others unharmed.

1 Dec 2020

Clonal hematopoiesis linked to severe COVID-19

Now, an international team of researchers from the USA, South Korea and Canada has found that clonal hematopoiesis is tied to the risk of severe COVID-19.

30 Nov 2020

Scientists use new approach to chart the spread of drug-resistant hospital bacteria

Scientists have used genome sequencing to reveal the extent to which a drug-resistant gastrointestinal bacterium can spread within a hospital, highlighting the challenge hospitals face in controlling infections.

27 Oct 2020

Synthetic peptide can make multidrug-resistant bacteria sensitive to antibiotics

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a synthetic peptide that can make multidrug-resistant bacteria sensitive to antibiotics again when used together with traditional antibiotics, offering hope for the prospect of a combination treatment strategy to tackle certain antibiotic-tolerant infections.

6 Aug 2020

Raw-type dog food contains high levels of multidrug-resistant bacteria

Microorganisms that infect animals, such as dogs, have the potential to jump to humans and cause illness. Zoonosis is a disease that can spread from animals to humans. These diseases pose health risks, mainly that some types can become life-threatening. Now, a study warns that raw-type dog food contains high levels of multidrug-resistant bacteria, which has the potential of transmitting the bacteria between dogs and humans.

21 Apr 2020

Study: Early changes in microbiome development can impact health and disease later in life

A team of researchers at Children's Hospital of Philadelphia (CHOP) has characterized how the gut microbiome develops in the first hours of infancy, providing a critical baseline for how changes in this environment can impact health and disease later in life.

17 Apr 2020

Inadequate precleaning can jeopardize sterilization of surgical tools

Vaporized hydrogen peroxide failed to completely sterilize surgical tools 76 percent of the time when the tools were soiled with salts or blood and not cleaned prior to sterilization, according to a study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

26 Feb 2020

Researchers develop novel therapy to combat antibiotic-resistant superbug infections

There may be a solution on the horizon to combating superbug infections resistant to antibiotics. The tenacious bacteria and fungi sicken more than 2.8 million people and lead to more than 35,000 deaths in the United States each year.

20 Feb 2020

Chinese scientists suggest alternative strategy for combating obesity

Overweight and obesity have become a severe public health problem around the world. Current anti-obesity strategies are mainly aimed at restricting calorie intake and absorption. Now, Chinese scientists suggest in a new study that burning energy by activation of brown adipose tissue (BAT) might be an alternative strategy for combating obesity.

21 Nov 2019

Study shows potential of phage therapy to treat alcoholic liver disease

Bacteriophages (phages) are viruses that specifically destroy bacteria. In the early 20th century, researchers experimented with phages as a potential method for treating bacterial infections.

13 Nov 2019

Researchers use phage therapy to successfully treat alcoholic liver disease

Researchers have successfully used bacteriophage (phage) therapy to eliminate alcohol-related liver disease in an animal model.

13 Nov 2019

Researchers produce synthetic phages that attack broader range of bacterial strains

Bacteriophages ("phages" for short) are viruses that infect bacteria. Phages are highly host-specific and will typically only infect and kill an individual species or even subspecies of bacteria. Compared to conventional antibiotics, phages do not indiscriminately kill bacteria.

4 Nov 2019

Compound in human breast milk inhibits growth of pathogenic bacteria

Researchers at National Jewish Health and the University of Iowa have identified a compound in human breast milk that fights infections by harmful bacteria while allowing beneficial bacteria to thrive.

10 Oct 2019

Research: Potentially harmful microbes overwhelm healthy gut microbiota in ICU patients

Potentially harmful microbes overwhelm the healthy gut microbiota in intensive care patients, research has found.

1 Oct 2019

Mechanisms behind antibiotic resistance captured on video for the first time

Scientists have established the cause of antibiotic-resistance in bacteria on video, and the findings contradict previous beliefs.

26 Sep 2019

Scientists identify cause of antibiotic resistance

Scientists have confirmed for the first time that bacteria can change form to avoid being detected by antibiotics in the human body.

26 Sep 2019

Abnormal gut bacteria linked to poor cognitive performance in vets with PTSD and cirrhosis

A study involving military veterans with PTSD and cirrhosis of the liver points to an abnormal mix of bacteria in the intestines as a possible driver of poor cognitive performance--and as a potential target for therapy.

13 Sep 2019

Move to single-patient rooms reduced rates of hospital-acquired infections

The move to single-patient rooms at the McGill University Health Centre's Glen site in 2015 resulted in significantly reduced rates of hospital-acquired infections, suggests a study published today in the highly respected journal JAMA: Internal Medicine published by the American Medical Association.

21 Aug 2019