Enterovirus News and Research

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Deaths of Chinese children, adolescents from infectious diseases prior to COVID-19 found to be rare

Deaths of children and adolescents in China due to infectious diseases were becoming rare prior to the COVID-19 pandemic, according to a new study.

3 Apr 2020

Epiglottitis linked to teenager's use of e-cigarettes

A teenage girl with no hint of prior asthma or respiratory illness began to feel hoarseness in her throat and a feeling that she needed to clear her throat frequently.

5 Feb 2020

Observational study uncovers largest outbreak of neurologic illness to date in the U.S.

The Lancet Infectious Diseases recently published the results of an observational study led by researchers on Children's Hospital Colorado Infectious Disease and Neurology teams, along with counterparts at the Centers for Disease Control and Colorado Department of Public Health and Environment.

8 Jan 2020

Host cell calpain proteases can process enterovirus polyprotein in vitro, study shows

It has long been suggested that a cell protease could take part in enterovirus infection. However, the identity of such proteases have remained unknown.

4 Dec 2019

Virome analysis reveals clues for increased risk of type 1 diabetes in children

New results from The Environmental Determinants of Diabetes in the Young study show an association between prolonged enterovirus infection and the development of autoimmunity to the insulin-producing pancreatic beta-cells that precedes type 1 diabetes.

2 Dec 2019

Research findings can be used in antiviral development against enterovirus infections

Despite their prevalence, there are no antivirals on the market against enteroviruses, and vaccines have been developed only against couple of serotypes. The production of vaccines against all enterovirus serotypes is not feasible, and so antiviral drugs may be the solution for most of the enterovirus infections.

19 Nov 2019

Scientists discover novel virus that may shed light on viral evolution

Viruses are non-living creatures, consisting of genetic material encased in a protein coat. Once the virus infects a living organism, it can replicate itself and continue on. But what happens if a virus lacks the proper tools to infect an organism? How can it propagate?

16 Oct 2019

Stopping cold viruses dead by blocking replication

The common cold virus (and its more deadly cousins, the viruses that cause polio and acute flaccid myelitis) may just have met its nemesis. In a recent study published in the journal Nature Microbiology on September 16, 2019, scientists reported a potentially successful new approach to stop cold viruses from replicating inside human cells – by blocking the formation of a protein that is vital to this process.

17 Sep 2019

Stanford-UCSF researchers report new cure for common cold in human cells and mice

Temporarily disabling a single protein inside our cells might be able to protect us from the common cold and other viral diseases, according to a study led by researchers at Stanford University and University of California-San Francisco.

16 Sep 2019

Molecular mechanism of enterovirus infection uncovered

Researchers from the Nanoscience Center at the University of Jyväskylä in collaboration with those at the University of Helsinki have found that body proteins called albumin and certain ions within the attacked host cells can affect the genetic workings of enteroviruses and enhance their infection.

19 Aug 2019

Research reveals physiological events leading to successful enterovirus infection

Enteroviruses are one of the most common human pathogens leading to high number of acute and chronic infections worldwide.

19 Aug 2019

Scientists point to enterovirus infection as cause for acute flaccid myelitis

Scientists at the Center for Infection and Immunity at Columbia University Mailman School of Public Health, the U.S. Centers for Disease Control and Prevention, and the University of California San Diego report antibody evidence in cerebrospinal fluid that points to enterovirus infection as a cause for acute flaccid myelitis, a disease responsible for partially paralyzing more than 560 children in the United States since 2014. Results of the study appear in the journal mBio.

13 Aug 2019

Study provides evidence that enterovirus may be a factor in acute flaccid myelitis

A new study analyzing samples from patients with and without acute flaccid myelitis provides additional evidence for an association between the rare but often serious condition that causes muscle weakness and paralysis, and infection with non-polio enteroviruses.

13 Aug 2019

NIH contract awarded to UAB for acute flaccid myelitis natural history study

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded the University of Alabama at Birmingham approximately $10 million over 5 years to study acute flaccid myelitis, a rare but serious condition which causes muscle weakness and paralysis.

23 Jul 2019

Puzzling paralysis affecting healthy children warns CDC

The Centers for Disease Control and Prevention (CDC) has warned that a series of rare and difficult to treat cases of paralysis are being seen in otherwise healthy children since 2018. This outbreak is 2018 may soon make a comeback in 2020 the organization warns doctors and paediatricians. The report was published in the CDC’s Vital Signs this week.

11 Jul 2019

Scientists discover weakness in common cold virus

Scientists have discovered a weakness on the surface of the viruses that cause a multitude of illnesses.

12 Jun 2019

Viruses in the intestinal tracts can lead to islet autoimmunity and Type 1 diabetes

Researchers at the Center for Infection and Immunity at the Columbia University Mailman School of Public Health and the University of New South Wales, Sydney, Australia, provide new evidence supporting an association between elevated levels of enteroviruses in the intestinal tracts of children and islet autoimmunity, a precursor to Type 1 diabetes.

20 Feb 2019

Celiac disease may be caused by gastrointestinal infection in childhood

A new study has found that a childhood stomach bug may be the cause of celiac disease later in life. The findings could pave the way for a vaccine to protect against the disease.

15 Feb 2019

TGen identifies polio-like virus as potential cause of Acute Flaccid Myelitis outbreak

The Translational Genomics Research Institute, an affiliate of City of Hope, has identified a polio-like virus as a potential cause of an outbreak of a disease known as Acute Flaccid Myelitis (AFM), a crippling condition that causes muscle weakness and paralysis usually among children.

23 Jan 2019

Houston Methodist launches real-time website to track flu cases

Pathologists at Houston Methodist developed a real-time website to track flu cases, just in time to assist physicians, the CDC and patients for the fall 2018 flu season.

7 Dec 2018