Enterovirus 71 (EV71) News and Research

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Genetic-code expansion technique to potentially create next-generation vaccine candidate

A new experiment devised a novel method to manipulate virulent viruses in conventional laboratories and validated the prophylactic effect of this method in two mouse models.

13 Dec 2021

Researchers identify acrylamides that inhibit SARS-CoV-2 main protease

A new study in the preprint server bioRxiv published in November 2020 describes the discovery of acrylamide fragments that can effectively disable key enzymes in both the hand, foot and mouth virus and SARS-CoV-2 virus.

11 Nov 2020

The Virus That Causes Hand, Foot and Mouth Disease May Use Human Protein to Aid Infection

The human protein, prohibitin, may be used by the virus to enter motor neurons and cause the neurological complications of hand, foot and mouth disease.

12 Jan 2018

Clinicoradiological syndromes allow rapid recognition of EV71 neurological problems

Severe enterovirus 71 neurological disease in children predominantly involves the spinal cord and brainstem and can be quickly recognised using the World Health Organisation classification of clinicoradiological syndromes, study findings suggest.

29 Jan 2016

Study reveals new invasion mechanism of Enterovirus 71

A new study determines glycosylation and pH-dependent conformational changes of virus receptor SCARB2 as crucial for EV71 attachment, entry and uncoating.

21 Jul 2014

Researchers discover potential treatment for viral infection that causes illnesses in children

Researchers have discovered a potential treatment for a viral infection that causes potentially fatal brain swelling and paralysis in children. The findings also point to possible treatments for related viruses including those that cause "common cold" symptoms.

29 Jan 2014

New lab at Diamond to help scientists delve into inner workings of pathogens

The UK's national synchrotron facility, Diamond Light Source, is now the first and only place in Europe where pathogens requiring Containment Level 3 - including serious viruses such as those responsible for AIDS, Hepatitis and some types of flu - can be analysed at atomic and molecular level using synchrotron light.

18 Feb 2013

Sinovac provides update on EV71 vaccine Phase III trial on HFMD

Sinovac Biotech Ltd., a leading provider of biopharmaceutical products in China, today provided an update on its Phase III clinical trial progress and commercialization preparation for its proprietary inactivated Enterovirus 71 (EV71) vaccine against hand, foot and mouth disease (HFMD).

26 Jun 2012

Sinovac third quarter sales increase 60.8% to $15.4 million

Sinovac Biotech Ltd., a leading provider of biopharmaceutical products in China, announced today its unaudited third quarter financial results for the period ended September 30, 2011.

14 Nov 2011

Sinovac second quarter sales increase 52.5% to $15.7 million

Sinovac Biotech Ltd., a leading provider of biopharmaceutical products in China, announced today its unaudited second quarter financial results for the period ended June 30, 2011.

12 Aug 2011

Inviragen commences INV21 Phase 1 trial against Hand, Foot and Mouth Disease

Inviragen announced today the initiation of the first clinical trial of the Company's proprietary Hand, Foot and Mouth Disease (HFMD) investigational vaccine, INV21, a highly purified virus particle preparation designed to protect against HFMD caused by enterovirus 71.

16 Jun 2011

Positive preliminary results from Sinovac EV71 vaccine phase I trial in adults

Sinovac Biotech Ltd., a leading provider of biopharmaceutical products in China, announced today the unblinding of the Phase I clinical trial results for the adult population for its proprietary inactivated vaccine against human enterovirus 71, which causes hand, foot, and mouth disease.

10 Mar 2011

Sinovac Beijing expands production capacity with acquisition of buildings and land use rights in Changping

Sinovac Biotech Ltd. (SVA), a leading China-based vaccine manufacturer, today announced the completion by its subsidiary, Sinovac Beijing, of the acquisition of buildings and land use rights. The total consideration for the purchase is approximately RMB120 million ($17.6 million), which will be financed from working capital. The initial payment of RMB56.5 million ($8.3 million) will be paid before February 20, 2010 and the balance of the purchase price will be paid in three installments within three years.

16 Feb 2010

Death toll in China now at 39 as 5 more children die from enterovirus 71

The death toll in China from enterovirus 71 (EV71) has risen to 39 with the deaths of five more children; EV71 belongs to the same family as the polio virus and is a strain of hand, foot and mouth disease (HFMD).

13 May 2008