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Unraveling the complex cellular composition of aldosterone-producing adenomas

Researchers from Tokyo Medical and Dental University (TMDU) find that the cells that make up aldosterone-producing adenomas become more transcriptionally active and express higher levels of genes linked to hormone production over intratumoral differentiation.

1 Mar 2024

The association between diet and colorectal cancer risk

The genetic variants that modify the association between diet and colorectal cancer (CRC) risk.

1 Mar 2024

COVID-19's lasting mark: Long-term smell and taste loss

Study reveals prolonged olfactory and gustatory dysfunction in some COVID-19 recoverees, highlighting a need for better clinical support and understanding of long-term effects.

29 Feb 2024

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Researchers developed an engineered transcriptional repressor that durably silences the Pcsk9 gene in mice, reducing cholesterol levels for up to a year with a single treatment, showcasing a potential breakthrough in genetic disorder treatments without the risks of DNA mutation.

29 Feb 2024

Rare gene mutations in hereditary Alzheimer's disease disrupt amyloid production, study shows

A University of Kansas study of rare gene mutations that cause hereditary Alzheimer's disease shows these mutations disrupt production of a small sticky protein called amyloid.

29 Feb 2024

Breakthrough CRISPR technique unlocks insights about cancer immunology

Over the past two decades, the immune system has attracted increasing attention for its role in fighting cancer.

29 Feb 2024

Novel malaria test by Rice University offers rapid diagnosis and treatment

Rice University researchers have developed a rapid, accurate test for diagnosing malaria that is significantly faster and easier to use than traditional tests.

29 Feb 2024

EPFL scientists uncover protein degradation mechanism preventing autoimmune reactions

Scientists at EPFL uncover the mechanism by which cells mark the protein cGAS for degradation, which is critical in preventing the immune system from mistakenly attacking the body's own tissues.

28 Feb 2024

UB research may offer a more streamlined approach to developing cancer drugs

Drug discovery can be a frustrating process of trial and error.

28 Feb 2024

Scientists uncover a new doorway for SARS-CoV-2 into human cells

Research identifies the human transferrin receptor as an alternative pathway for SARS-CoV-2 infection, offering potential new targets for COVID-19 therapies.

27 Feb 2024

Resistant starch diet proves a game changer for weight loss and diabetes control

Supplementation with resistant starch leads to weight loss and improved insulin sensitivity by altering the gut microbiome and increasing secondary bile acids, according to a recent study in Nature Metabolism.

27 Feb 2024

UMass Amherst study targets aplastic anemia with cell retraining approach

Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study that focuses on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the overzealous immune response that can lead to fatal autoimmune disorders.

27 Feb 2024

Innovative Subak tool offers affordable solution for detecting nuclease digestion

A new tool could reduce costs for diagnosing infectious diseases.

27 Feb 2024

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in the top-class journal Cellular & Molecular Immunology, has a promising result from tumor research: The enzyme phosphoglycerate dehydrogenase (PHDGH) acts as a metabolic checkpoint in the function of tumor-associated macrophages (TAMs) and thus on tumor growth.

27 Feb 2024

Optibrium launches a metabolism prediction software platform tailored to DMPK scientists

Semeta™ offers high sensitivity and superior precision for the prediction of Phase I and II metabolic routes, sites, products and liabilities in early drug discove.ry

From Optibrium Ltd. 27 Feb 2024

Spirulina shows promise in battling heart disease and diabetes

Researchers show Spirulina's therapeutic benefits, including anti-inflammatory and antidiabetic properties, can significantly lower cardiovascular disease risk.

26 Feb 2024

Vaping increases susceptibility to COVID-19 infection, study finds

Vapers are susceptible to infection by SARS-CoV-2, the virus that spreads COVID-19 and continues to infect people around the world, a University of California, Riverside, study has found.

26 Feb 2024

Breakthrough research unveils β-cell dynamics in Type 1 diabetes

About eight million people live with Type 1 diabetes (T1D) worldwide, a chronic autoimmune condition in which the body attacks and destroys its own insulin-producing β-cells (pronounced "beta") in the pancreas, leading to a lack of insulin and inability to regulate blood sugar.

26 Feb 2024

Understanding obesity's effects on liver metabolism

Your liver plays a vital role in your metabolism, the biological process which converts food into energy.

26 Feb 2024

SARS-CoV-2-infection and vaccine-induced antibodies wane initially but stabilize for lasting protection

A study published in Immunity shows that antibody responses to SARS-CoV-2 infection and vaccination are long-lasting, with an initial decline followed by stabilization after seven to nine months, highlighting the effectiveness of mRNA vaccines and the importance of hybrid immunity.

25 Feb 2024

Enzyme News and Research

Unraveling the complex cellular composition of aldosterone-producing adenomas

The association between diet and colorectal cancer risk

COVID-19's lasting mark: Long-term smell and taste loss

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Rare gene mutations in hereditary Alzheimer's disease disrupt amyloid production, study shows

Breakthrough CRISPR technique unlocks insights about cancer immunology

Novel malaria test by Rice University offers rapid diagnosis and treatment

EPFL scientists uncover protein degradation mechanism preventing autoimmune reactions

UB research may offer a more streamlined approach to developing cancer drugs

Scientists uncover a new doorway for SARS-CoV-2 into human cells

Resistant starch diet proves a game changer for weight loss and diabetes control

UMass Amherst study targets aplastic anemia with cell retraining approach

Innovative Subak tool offers affordable solution for detecting nuclease digestion

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

Optibrium launches a metabolism prediction software platform tailored to DMPK scientists

Spirulina shows promise in battling heart disease and diabetes

Vaping increases susceptibility to COVID-19 infection, study finds

Breakthrough research unveils β-cell dynamics in Type 1 diabetes

Understanding obesity's effects on liver metabolism

SARS-CoV-2-infection and vaccine-induced antibodies wane initially but stabilize for lasting protection

Biochemistry eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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