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Immune antibodies penetrate neurons to clear Alzheimer's-linked amyloid

Researchers at Weill Cornell Medical College have gotten much closer to understanding how immune-based therapies can treat Alzheimer's disease -- by studying how antibodies go inside brain cells to reduce levels of Alzheimer's-linked amyloid peptides that form plaques between neurons.

24 May 2007

Tool will revolutionise functional genomic studies in clostridia

The genome of the organism that produces the world's most lethal toxin has been revealed.

24 May 2007

New understanding of how immune-based therapies can treat Alzheimer's disease

24 May 2007

Novel preclinical gene therapy approach for treating Niemann-Pick disease

Genzyme Corp. has announced the publication of a new study in The Proceedings of the National Academy of Sciences describing a novel preclinical gene therapy approach for treating Niemann-Pick disease.

24 May 2007

University of Leicester launches one-year Masters degree in Cancer Chemistry

The degree is the first of its kind in the country, fulfilling a need to provide graduates with skills in the chemistry and biology of cancer, and direct experience of some of the very latest research in the field.

22 May 2007

Flash-heating breast milk infected with HIV successfully deactivates virus

A simple method of flash-heating breast milk infected with HIV successfully inactivated the free-floating virus, according to a new study led by researchers at the Berkeley and Davis campuses of the University of California.

22 May 2007

Suicide gene therapy kills bowel cancer cells

An innovative type of gene therapy has for the first time succeeded in making bowel cancer cells commit suicide, according to a report in Cancer Research.

20 May 2007

Scientists develop method to track immune system enzyme in live animals

Scientists supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health have created two mouse strains that will permit researchers to trace, in a live animal, the activity of an enzyme believed to play a crucial role both in the normal immune response as well as autoimmunity and B cell tumor development.

18 May 2007

Lowering a patient's temperature could aid standard stroke treatment

University of Cincinnati (UC) scientists have developed a model that could help physicians combine current clot-busting medication with below-normal body temperatures (hypothermia) to improve the treatment of ischemic stroke patients.

18 May 2007

Nutrition and heredity genetically linked

A challenging goal in biology is to understand how the principal cellular functions are integrated so that cells achieve viability and optimal fitness under a wide range of nutritional conditions.

17 May 2007

ACE inhibitors help preserve kidney function in IgA nephropathy

For young patients with the kidney disease IgA nephropathy (IgAN), early treatment with angiotensin-converting enzyme (ACE) inhibitors can reduce the long-term risk of irreversible kidney damage, suggests a study in the June Journal of the American Society of Nephrology.

17 May 2007

Study revises dynamin's role in nerve cell function

An unexpected finding on how nerve cells signal to one another could rewrite the textbooks on neuroscience, says a collaborative team of researchers at Weill Cornell Medical College and Yale University.

17 May 2007

Model of proline dehydrogenase created

Researchers at the University of Missouri-Columbia recently created a model of proline dehydrogenase, an important cancer-preventing enzyme in the human body, and analyzed how it works.

17 May 2007

Potential therapeutic target for autoimmune vasculitis

A potential therapeutic target for autoimmune vasculitis has been identified by researchers of the Franz Volhard Clinic for Cardiovascular Diseases (FVK) of the Charity – University Medicine Berlin/HELIOS-Klinikum and the Max Delbruck Center for Molecular Medicine (MDC) Berlin-Buch.

16 May 2007

Estrogen may influence the risk for prostate cancer

Although women are four times more likely than men to develop osteoporosis, or porous bone, one in 12 men also suffer from the disease, which can lead to debilitating - or even life-threatening - fractures, mainly of the spine, hip and wrist.

11 May 2007

Low frequency of resistance to Tamiflu confirmed

New data published by the World Health Organisation (WHO) has confirmed a low frequency of resistance to Tamiflu (oseltamivir) over 3 influenza seasons (2003:2006).

10 May 2007

Review of six large-scale clinical trials of aliskiren

Hypertension is a serious condition affecting millions.Currently there are seven classes of drugs used to reduce blood pressure. Aliskiren (Tekturna , Rasilez) is the first of a new class of orally active antihypertensive drugs that works by inhibiting renin.

10 May 2007

Researchers watch repair proteins arrive around DNA breaks

Investigators at St. Jude Children's Research Hospital had a molecule's eye view of the human cell's DNA repair kit as it assembled on a double-strand break to link together the broken ends.

10 May 2007

Bipolar disorder - the clue may be in the genes

The first scan of the entire human genetic code has revealed that developing bipolar disorder may to some extent depend on the combined effects of variations in many different genes in the brain, none of which is powerful enough to cause the disease by itself.

9 May 2007

Researchers develop first antibody that detects gene mutations that cause amyotrophic lateral sclerosis

Researchers at the University of Toronto's Faculty of Medicine have developed the first antibody that detects the only known cause of amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease.

9 May 2007