Enzyme Linked Immunosorbent Assay (ELISA) News and Research

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Comparison of neutralizing antibody response following SARS-CoV-2 booster vaccination with breakthrough infection

A new study examined the serological immune responses and antibody-dependent cell-mediated phagocytosis in individuals who had either received two doses of a standard vaccine regime, a booster dose following the regime, or a breakthrough infection following vaccination.

15 Apr 2022

mRNA vaccines induce CD8+ T cells that may reduce COVID-19 severity

In a recent study under consideration at Nature Portfolio Journal and posted to the Research Square* preprint server, researchers characterized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S)-specific cluster of differentiation 8 (CD8+) T cell responses.

12 Apr 2022

Development of 18 monoclonal antibodies against 9 SARS-CoV-2 proteins

A new study aimed to generate, characterize, and optimize Abs against SARS-CoV-2 proteins.

12 Apr 2022

NVX-CoV2373 vaccine found to induce functional SARS-CoV-2-specific T cell responses

In a recent study researchers evaluated the T cell responses elicited by full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein vaccine NVX-CoV2373.

12 Apr 2022

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Researchers used cryogenic electron microscopy (cryo-EM) to determine the structure of the spike (S) protein of BA.2 sub-variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) and compared them with previously determined S structures of Omicron's BA.1 sub-variant.

11 Apr 2022

Evaluating immunogenicity after BNT162b2 booster vaccination

Researchers assessed the levels of IgG and IgA antibodies in sera samples from healthcare workers before vaccination, after the first vaccine dose, after eight months, and after a booster shot.

8 Apr 2022

Study characterizes SARS-CoV-2 spike-specific cluster of differentiation 4+ T-cell response

In a new study, researchers characterized over 100 SARS-CoV-2-specific CD4+ T-cell epitopes.

8 Apr 2022

Improved seroprevalence and antibody response after third COVID-19 vaccination

Researchers evaluated the immunogenicity of a third COVID-19 vaccination in antibody deficient subjects.

8 Apr 2022

Study suggests blunted serological responses not responsible for COVID-19 mortality

A new study investigated serological profiling to determine the antibody responses in critically ill COVID-19 positive and negative patients.

7 Apr 2022

Researchers explore the link between immunoglobulins and blood profile in severe SARS-CoV-2 patients

A new study illustrated the association of immunoglobulins with blood characteristics in COVID-19 patients.

6 Apr 2022

Study evaluates the presence of the SARS-CoV-2 spike protein in urine samples collected during the COVID-19 pandemic

A study published analyzed the presence of SARS-CoV-2 spike protein in urine samples of the infected patients.

6 Apr 2022

Recombinant fragment of the lectin-binding region of Gal-3BP stimulates the expression of IL-6 in SARS-CoV-2 sensitive cells

A recent study investigated the impact of a recombinant fragment of cellular glycoprotein Gal-3BP on IL-6 expression in acute COVID-19.

5 Apr 2022

Prior COVID vaccination induces a more robust antibody response to Omicron

A recent study posted to the medRxiv* preprint server assessed the impact of prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination on the human immune response against SARS-CoV-2 Omicron infection.

5 Apr 2022

Magnitude and durability of SARS-CoV-2 S-binding antibody titers in the pre-variant era among healthcare workers in NYC

Researchers analyzed sera samples of 400 participants of the PARIS study to evaluate the risk of SARS-CoV-2 infection and seroreversion for an average of 84 days.

4 Apr 2022

Study shows SARS-CoV-2 antibodies persist for one-year post-infection with protection from other variants

Researchers discussed the stability of spike antibody titers mounted against SARS-CoV-2 infection, and their ability to protect from infection with antigenically similar variants.

4 Apr 2022

Researchers explore a novel method to isolate monoclonal antibodies from COVID-19 convalescents infected with SARS-CoV-2 variants

Researchers developed a novel high-throughput method to obtain monoclonal antibodies from COVID-19 individuals infected with SARS-CoV-2 ancestral strain Wuhan-Hu-1 and the Beta or Gamma variants.

1 Apr 2022

Study identifies a new class of monoclonal antibodies that neutralize both alpha and beta coronaviruses

A team of international scientists has recently isolated and characterized pan-coronavirus neutralizing antibodies from individuals with pre-existing immunity against SARS-CoV-2.

1 Apr 2022

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Researchers bioengineered a divalent fusion vaccine by combining the immunogenic region of the nucleocapsid protein and the receptor-binding domain of the spike protein of SARS-CoV-2.

30 Mar 2022

Engineering rotavirus-based vaccine vectors expressing SARS-CoV-2 spike epitopes

Researchers proposed rotavirus-based vaccine vectors with the potential for developing polyvalent vaccines targeting multiple enteric viruses, including SARS-CoV-2.

30 Mar 2022

A ferritin nanoparticle candidate vaccine for COVID

In a recent study published on the bioRxiv* preprint server, the immunogenicity, and effectiveness of SARS-CoV-2 spike ferritin nanoparticle (SpFN) adjuvanted with aluminum hydroxide (AlOH3) or Army Liposomal Formulation QS-21 (ALFQ) in a cynomolgus macaque (CM) COVID-19 model was evaluated.

30 Mar 2022

Enzyme Linked Immunosorbent Assay (ELISA) News and Research

Comparison of neutralizing antibody response following SARS-CoV-2 booster vaccination with breakthrough infection

mRNA vaccines induce CD8+ T cells that may reduce COVID-19 severity

Development of 18 monoclonal antibodies against 9 SARS-CoV-2 proteins

NVX-CoV2373 vaccine found to induce functional SARS-CoV-2-specific T cell responses

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Evaluating immunogenicity after BNT162b2 booster vaccination

Study characterizes SARS-CoV-2 spike-specific cluster of differentiation 4+ T-cell response

Improved seroprevalence and antibody response after third COVID-19 vaccination

Study suggests blunted serological responses not responsible for COVID-19 mortality

Researchers explore the link between immunoglobulins and blood profile in severe SARS-CoV-2 patients

Study evaluates the presence of the SARS-CoV-2 spike protein in urine samples collected during the COVID-19 pandemic

Recombinant fragment of the lectin-binding region of Gal-3BP stimulates the expression of IL-6 in SARS-CoV-2 sensitive cells

Prior COVID vaccination induces a more robust antibody response to Omicron

Magnitude and durability of SARS-CoV-2 S-binding antibody titers in the pre-variant era among healthcare workers in NYC

Study shows SARS-CoV-2 antibodies persist for one-year post-infection with protection from other variants

Researchers explore a novel method to isolate monoclonal antibodies from COVID-19 convalescents infected with SARS-CoV-2 variants

Study identifies a new class of monoclonal antibodies that neutralize both alpha and beta coronaviruses

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Engineering rotavirus-based vaccine vectors expressing SARS-CoV-2 spike epitopes

A ferritin nanoparticle candidate vaccine for COVID

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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