Eosinophil News and Research

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Eosinophils are a specialized type of cell within the immune system that are involved in anti-parasitic and inflammatory responses.

FENO and B-Eos complement each other as asthma biomarkers

Research indicates that fraction of exhaled nitric oxide and blood eosinophil count values can independently predict asthma diagnosis and attacks.

8 Oct 2013

Chronic bronchitis linked to poor asthma outcomes

Researchers have found that chronic bronchitis is associated with worse clinical outcomes in asthma, particularly among smokers.

26 Sep 2013

Researchers identify new link between meal times and daily changes in immune system

A new link between meal times and daily changes in the immune system has been identified by UC San Francisco researchers, and has led them to question assumptions about the roles of specific immune cells in infection and allergy.

17 Sep 2013

Researchers identify new culprit that likely plays big role in severity of asthma

MD-A new culprit has been identified that likely plays a big role in the severity of asthma-a small protein chemokine called CCL26. These findings were published in the Journal of Leukocyte Biology and represent the first demonstration that CCL26 is a potent regulator of the migration of asthmatic eosinophils, commonly observed in asthmatic airways. Results from this discovery may lead to new drug targets for the treatment of asthma.

2 Aug 2013

Atopy’s immunologic properties change with age in asthma

The strength of interaction between atopy and elevated eosinophil levels in asthma decreases with age, a study finds.

30 Apr 2013

IP-10 and neopterin show promise as biomarkers for lung disease exacerbations

Australian researchers have identified interferon-γ inducible protein-10 and neopterin as promising sputum markers of acute exacerbations of obstructive lung disease.

29 Apr 2013

FAP cells help in repairing injured muscles

UC San Francisco scientists have discovered that muscle repair requires the action of two types of cells better known for causing inflammation and forming fat.

20 Apr 2013

Severe childhood asthma blood test hopes dashed

Blood eosinophil counts do not reliably reflect airway eosinophil concentrations in children with severe, therapy-resistant asthma, and therefore cannot be used to make therapeutic decisions, researchers report.

19 Feb 2013

Eosinophilic inflammation of the esophagus relieved by diet

A diet that eliminates six food types has proved effective at inducing remission of eosinophilic esophagitis in adults, report researchers.

18 Feb 2013

Etanercept no better than prednisone for COPD exacerbations

Results from a randomized, double-blind, controlled trial suggest that the tumor necrosis factor α antagonist etanercept is no more effective than standard therapy with prednisone for the treatment of acute exacerbations in patients with chronic obstructive pulmonary disease.

8 Feb 2013

High-altitude treatment may help severe asthma patients

Individuals with severe refractory asthma may benefit from high-altitude treatment, irrespective of their sensitivity to airborne allergens, suggest findings from a study conducted in the Swiss Alps.

11 Dec 2012

Smoking affects development of peripheral allergy-relevant stem cells in the blood

Environmental contaminants, such as smoking, are harmful to the human organism in relation to the occurrence of allergies. This is known. Until now, researchers had never investigated whether and to what extent environmental contaminants also affect allergy-relevant stem cells.

15 Nov 2012

Simple new test can monitor treatment of eosinophilic esophagitis

A simple new test, in which the patient swallows a string, can monitor treatment of eosinophilic esophagitis as effectively as an invasive, expensive and uncomfortable procedure that risks complications, particularly in children.

4 Oct 2012

Biopsies may misdiagnose eosinophilic esophagitis

University of Utah engineers mapped white blood cells called eonsinophils and showed an existing diagnostic method may overlook an elusive digestive disorder that causes swelling in the esophagus and painful swallowing.

7 Sep 2012

Meritage commences OBS Phase 2 clinical trial for eosinophilic esophagitis

Meritage Pharma, Inc. announced that it has initiated a Phase 2 clinical trial to evaluate oral budesonide suspension (OBS) for the treatment of adolescents and young adults with eosinophilic esophagitis (EoE), an allergic inflammatory condition of the esophagus. EoE is a chronic disease characterized by symptoms related to esophageal dysfunction and eosinophil-predominant inflammation.

13 Aug 2012

Eosinophil count predicts mortality risk following heart procedure

Study findings suggest that eosinophil count predicts mortality risk in patients undergoing percutaneous coronary intervention.

12 Jul 2012

Eosinophil count predicts mortality risk following heart procedure

Study findings suggest that eosinophil count predicts mortality risk in patients undergoing percutaneous coronary intervention.

10 Jul 2012

Airway inflammation linked with asthma-related mortality rates in older adults

Higher mortality rates among older adult asthma patients compared to their younger counterparts may be due, at least in part, to an increase in airway inflammation, according to a study conducted by researchers in Canada, who note that their results imply that elderly patients are either less likely to follow asthma medication dosing instructions, or that the underlying airway inflammation in elderly patients is relatively resistant to current anti-inflammatory therapies.

22 May 2012

Coronary stents do not increase risk of heart attack, death in people with metal allergies

Cardiologists have long grappled with how to best manage patients with coronary artery disease who report skin hypersensitivity to nickel or other metal components found in stents -- small tubes placed in narrowed or weakened arteries to help improve blood flow to the heart. But new Mayo Clinic research, published in the April 16, 2012, issue of Circulation: Cardiovascular Interventions, may help allay these concerns.

17 Apr 2012

Researchers identify genetic signature for eosinophilic esophagitis

Researchers have identified a genetic signature for a severe, often painful food allergy – eosinophilic esophagitis – that could lead to improved diagnosis and treatment for children unable to eat a wide variety of foods.

12 Mar 2012