Ependymoma News and Research

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Researchers identify simple, inexpensive tool for assessing prognosis of pediatric brain tumors

A multi-institutional group of researchers, led by investigators at Children's Hospital Los Angeles and the University of Michigan, have identified a simple and inexpensive tool for assessing the prognosis of pediatric brain tumors called ependymomas.

23 Nov 2016

Sophisticated technology helps model and simulate optimal dose for pediatric ependymoma patients

St. Jude Children's Research Hospital scientists have used sophisticated pharmacologic modeling and simulation to translate preclinical findings into a successful phase I clinical trial of a chemotherapy agent for treatment of ependymoma. The research marked the first time the approach has been used to calculate drug doses for a clinical trial in pediatric brain tumor patients.

10 May 2016

New nationwide survey shows steady increase in pediatric patients treated with proton radiation therapy

Results from a new nationwide survey announced today indicate a steady increase in the number of pediatric patients who are being treated with proton radiation therapy for cancerous and non-cancerous tumors.

24 May 2015

Increasing radiotherapy can significantly improve survival for children with intracranial ependymoma

Two studies to be presented today (Sunday) at the 3rd ESTRO Forum in Barcelona, Spain, show that increasing the dose of radiotherapy given to children with an intracranial ependymoma, a form of cancer of the central nervous system, can significantly improve their survival.

27 Apr 2015

Plymouth University enters partnership with Brain Tumour Research

Patients, carers, scientists, clinicians and charities from across the UK are heading to Westminster today for the launch of a ground-breaking new collaborative partnership between the charity Brain Tumour Research and Plymouth University Peninsula Schools of Medicine and Dentistry. The announcement will open a new chapter in long-term sustainable and continuous research into the biggest cancer killer of children and adults under 40.

5 Mar 2014

Plymouth becomes active research partner with Brain Tumour Research

Plymouth University Peninsula Schools of Medicine and Dentistry will now become an active research and fundraising partner with Brain Tumour Research. The charity will support research and supply dedicated members of staff with expertise in fundraising, marketing and PR to work at both local and national levels alongside existing teams, creating a dynamic fundraising programme.

5 Mar 2014

Pediatric Cancer Genome Project identifies genetic alteration in brain tumor ependymoma

The St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project has identified the most common genetic alteration ever reported in the brain tumor ependymoma and evidence that the alteration drives tumor development. The research appears February 19 as an advanced online publication in the scientific journal Nature.

20 Feb 2014

Chromosomal abnormality in children with ependymoma linked with poorer chance of survival

A chromosomal abnormality in children with a deadly form of brain cancer is linked with a poorer chance of survival, clinician scientists at The University of Nottingham have discovered.

29 Mar 2012

Researchers identify promising new therapies for ependymoma

Researchers have identified promising new therapies for ependymoma, a rare tumor with few treatment options. St. Jude Children's Research Hospital investigators led the effort, which used a new, faster drug development system that combines the latest drug screening technology with the first accurate animal model of the tumor.

16 Sep 2011

Largest ever molecular-genetic study of ependymomas of the cerebellum

Ependymomas are the second most frequent type of malignant brain tumor in children. Ependymoma develops from precursor cells of the tissue that lines the hollow cavities of the brain. Therapy results of ependymoma vary immensely: While in some patients tumor growth comes to a standstill after surgery and radiotherapy, in other children the disease rapidly takes a severe course.

24 Aug 2011

Investigators to examine how Ephb2 gene causes ependymoma in children

Armed with new grant support, investigators at Nationwide Children's Hospital plan to examine how a common gene of the nervous system leads to the development of a devastating brain tumor, ependymoma.

2 Jun 2011

New research into drugs to prevent brain tumours in children wins vital funding

New research into drugs which could prevent the return of persistent brain tumours in children has won vital funding from two major brain tumour charities.

5 Mar 2011

Medulloblastoma subtypes are separate diseases with different origins

International effort led by St. Jude Children's Research Hospital scientists is expected to fuel development of targeted therapies and aid the search for unique combinations of cells and mutations that lead to other cancers.

8 Dec 2010

Childhood brain tumor survivors may be vulnerable to physical declines associated with aging: Study

A large study focused on documenting the strength and fitness of childhood brain tumor survivors has found that many face health challenges as they age. The study led by St. Jude Children's Research Hospital investigators showed that although most participants were young adults in their 20s, many functioned like people in their 60s, making them less likely to live independently or attend college.

16 Aug 2010

New approach to understand different cancer subtypes

An international team led by St. Jude Children's Research Hospital scientists finds unique combinations of cells and mutations lie at the heart of cancer subgroup revealed for the first time in a pediatric brain tumor

20 Jul 2010

Phase 1 study data of Keryx' perifosine for recurrent pediatric solid tumors presented at ASCO

Keryx Biopharmaceuticals, Inc. today announced that Phase 1 data of KRX-0401 (perifosine) in recurrent pediatric solid tumors was presented yesterday in the pediatric solid tumor poster discussion session held at the 46th Annual Meeting of the American Society of Clinical Oncology (ASCO) taking place in Chicago, IL.

7 Jun 2010

Ependymoma News and Research

Researchers identify simple, inexpensive tool for assessing prognosis of pediatric brain tumors

Sophisticated technology helps model and simulate optimal dose for pediatric ependymoma patients

New nationwide survey shows steady increase in pediatric patients treated with proton radiation therapy

Increasing radiotherapy can significantly improve survival for children with intracranial ependymoma

Plymouth University enters partnership with Brain Tumour Research

Plymouth becomes active research partner with Brain Tumour Research

Pediatric Cancer Genome Project identifies genetic alteration in brain tumor ependymoma

Chromosomal abnormality in children with ependymoma linked with poorer chance of survival

Researchers identify promising new therapies for ependymoma

Largest ever molecular-genetic study of ependymomas of the cerebellum

Investigators to examine how Ephb2 gene causes ependymoma in children

New research into drugs to prevent brain tumours in children wins vital funding

Medulloblastoma subtypes are separate diseases with different origins

Childhood brain tumor survivors may be vulnerable to physical declines associated with aging: Study

New approach to understand different cancer subtypes

Phase 1 study data of Keryx' perifosine for recurrent pediatric solid tumors presented at ASCO

Scientists identify ependymoma genes

New ependymoma genes identified

Chemotherapy beneficial for children with intracranial ependymoma

Chemo instead of radiotherapy cuts long-term side effects for children with brain tumours

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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