Epigenomics News and Research

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S&P Capital IQ commences Standard & Poor's Factual Stock Report coverage on Epigenomics AG

S&P Capital IQ announced today that it has commenced Standard & Poor's Factual Stock Report coverage on Epigenomics AG.

7 Sep 2013

Study shows genetic test to classify gastric cancers and match them to therapies offer best outcomes

Stomach cancer, one of the leading causes of cancer death worldwide, actually falls into three broad subtypes that respond differently to currently available therapies, according to researchers at Duke-NUS Graduate Medical School Singapore.

28 Aug 2013

Findings uncover epigenomic modification that occurs during brain formation

Changes in the epigenome, including chemical modifications of DNA, can act as an extra layer of information in the genome, and are thought to play a role in learning and memory, as well as in age-related cognitive decline.

5 Jul 2013

Modifications in key epigenetic markers influence human embryonic stem cells

Scientists have long known that control mechanisms known collectively as "epigenetics" play a critical role in human development, but they did not know precisely how alterations in this extra layer of biochemical instructions in DNA contribute to development.

10 May 2013

Salk epigenetic findings may aid in crop production and study of human diseases

Scientists at the Salk Institute for Biological Studies have identified patterns of epigenomic diversity that not only allow plants to adapt to various environments, but could also benefit crop production and the study of human diseases.

7 Mar 2013

Article provides examples of how epigenetic drug treatments could be beneficial in treating cancers

A review article by researchers at Boston University School of Medicine (BUSM) proposes a new epigenetic hypothesis linked to tumor production and novel ideas about what causes progenitor cells to develop into cancer cells. Published in the February 2013 issue of Epigenomics, the article provides examples of how epigenetic drug treatments could be beneficial in treating cancers while also decreasing the likelihood of cancer relapse.

21 Feb 2013

Scientists determine specific genetic switches that sync liver activity to the circadian cycle

When it's dark, and we start to fall asleep, most of us think we're tired because our bodies need rest. Yet circadian rhythms affect our bodies not just on a global scale, but at the level of individual organs, and even genes.

12 Dec 2012

Special issue of Disease Markers explores ASD genetics and biomarker development

Autism spectrum disorders (ASD) are neurodevelopmental disorders typically characterized by difficulties in social interactions and delayed or abnormal language development. Although ASD reportedly affects 1 in 88 people in the United States, to date there have been no distinctive biomarkers to diagnose the disease.

30 Nov 2012

New detection method can identify genetic switches associated with breast cancer

Physicians may now be better at detecting breast cancer than ever before, but much more work remains to ensure accurate diagnosis is possible and especially to assess future risk. That's why researchers from Germany have been working to develop a new test of gene action to predict cancer risk both at first diagnosis and into the future.

30 Nov 2012

Study provides new insight into human cognitive function and risk for neurological diseases

Short snippets of DNA found in human brain tissue provide new insight into human cognitive function and risk for developing certain neurological diseases, according to researchers from the Departments of Psychiatry and Neuroscience at Mount Sinai School of Medicine. The findings are published in the November 20th issue of PLoS Biology.

22 Nov 2012

RainDance's ThunderStorm System for targeted sequencing selected by UCL Cancer Institute

RainDance Technologies, Inc., the Digital Biology Company, today announced that the University College London (UCL) Cancer Institute has adopted its ThunderStorm System as a centralized platform for the validation of genomic and epigenomic targets from clinical and non-clinical studies, including follow-ups for genome-wide and epigenome-wide association studies (GWAS and EWAS), as well as stratified cancer medicine and basic research.

15 Nov 2012

Study identifies new prognostic biomarker and therapeutic target for adult B-ALL

New insight into the aggressive behavior of certain adult B-acute lymphoblastic leukemias has provided researchers with a potential new prognostic biomarker and a promising new therapeutic target.

30 Oct 2012

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

30 Oct 2012

Scientists decode epigenetic programming of three virulent forms of acute lymphoblastic leukemia

A team of national and international researchers, led by Weill Cornell Medical College scientists, have decoded the key "software" instructions that drive three of the most virulent forms of acute lymphoblastic leukemia (ALL). They discovered ALL's "software" is encoded with epigenetic marks, chemical modifications of DNA and surrounding proteins, allowing the research team to identify new potential biomarkers and therapeutic targets.

29 Oct 2012

New federal funding enables researchers to unravel how humans develop cancers

A Simon Fraser University scientist working at one of Canada's first epigenomics mapping centres says new federal funding will accelerate researchers' ability to unravel how we develop some of the most common life threatening cancers.

26 Oct 2012

New study decodes complete epigenome of chronic lymphocytic leukemia

Researchers of the University of Oviedo have contributed to decipher the first epigenomes of chronic lymphocytic leukemia.

20 Oct 2012

Genome-wide epigenomic screening can pinpoint thyroid disease-associated variants

Genome-wide epigenomic screening can pinpoint disease-associated variants and identify novel genetic-epigenetic interactions in autoimmune thyroid diseases, according to new data presented at the 82nd Annual Meeting of the American Thyroid Association (ATA) in Québec City, Québec, Canada.

24 Sep 2012

BMBF awards 16M€ to support German epigenome program initiative

The German Ministry for Research and Education (BMBF) will support the German epigenome program initiative "DEEP" with a budget of 16M€ over 5 years.

29 Aug 2012

PedBrain Tumor network publishes evaluation of first 125 genome analyses of medulloblastomas

Brain tumors are the primary cause of cancer mortality in children. Even if a cure is possible, young patients often suffer from the stressful treatment which can be harmful to the developing brain. The most common childhood brain tumors are medulloblastoma and pylocytic astrocytoma.

27 Jul 2012

Scientists discover new type of dynamic change in human stem cells

A team led by scientists at The Scripps Research Institute and the University of California (UC) San Diego has discovered a new type of dynamic change in human stem cells.

4 May 2012