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Faster, less expensive technique for mutating large, non-gene stretches of DNA

Genes account for only 2.5 percent of DNA in the human genetic blueprint, yet diseases can result not only from mutant genes, but from mutations of other DNA that controls genes.

19 Jun 2007

Better understanding of how the body fights off mucosal pathogens

In a finding that could have important implications for HIV vaccine research, new research at Weill Cornell Medical College illuminates the ways in which the body prevents its mucosal surfaces from being overwhelmed by bacteria.

17 Jun 2007

Baxter supports better access to pandemic flu treatment in developing world

Baxter International Inc. has expressed its continued support of the World Health Organization's (WHO) pandemic planning programs through participation in a planned international stockpile program.

From Baxter International Inc. 17 Jun 2007

HIV uses pathways to infect cells

Like hobos on a train, HIV, the virus that causes AIDS, uses a pre-existing transport system to leave one infected cell and infect new ones, Hopkins scientists have discovered.

8 Jun 2007

FDA provides guidance to help increase supply of influenza vaccines

The U.S. Food and Drug Administration (FDA) has issued final recommendations to increase the supply of safe and effective influenza vaccines for both seasonal and pandemic use.

3 Jun 2007

Device to treat brain cancer shows promise

New early data showed that an investigational device that specifically targets rapidly growing cancer cells with intermediate frequency electrical fields -- called Tumor-Treating Fields (TTFields) -- more than doubled the median overall survival rates in patients with recurrent glioblastoma multiforme (GBM), the most common and aggressive type of malignant brain tumor.

1 Jun 2007

Investigational device to treat brain cancer shows promise in early studies

30 May 2007

Researchers explore the glycosylation process

By studying the addition of sugars to proteins — a process called glycosylation — in the nervous system of insects, Temple University researcher Karen Palter believes she may be able to better understand neurodegenerative diseases in humans.

28 May 2007

FDA committee votes in favor of Acambis' smallpox vaccine

Acambis plc announced that the Vaccines and Related Biological Products Advisory Committee of the US Food and Drug Administration (FDA) voted unanimously that Acambis' smallpox vaccine, ACAM2000, is both safe and efficacious.

18 May 2007

Culture techniques can significantly affect cell growth and function

When it comes to growing cells in a lab, technique matters. A new Brown University study shows that nerve cells grown in three-dimensional cultures use 1,766 genes differently compared to nerve cells grown in standard two-dimensional petri dishes.

17 May 2007

Researchers design cell culture test for assessing a compound's genetic toxicity - cheaper than animal tests

In the daunting marathon that leads to successful drugs, promising drug candidates must pass toxicity tests before entering clinical trials.

15 May 2007

New method allows for stem cell propagation and neurogenesis in cell culture

Researchers are now able to study stem cells from the brains of adult mice and their neurogenesis in long-term cell cultures.

26 Apr 2007

Non-coplanar PCBs and related chemicals warrant serious attention for health reasons

Scientists have determined that a specific class of PCB causes significant developmental abnormalities in rat pups whose mothers were exposed to the toxicant in their food during pregnancy and during the early weeks when the pups were nursing.

24 Apr 2007

Natural ingredient in human blood found to block HIV-1

A new study has pinpointed a natural ingredient of human blood that effectively blocks HIV-1, the virus predominantly responsible for human AIDS, from infecting immune cells and multiplying.

20 Apr 2007

Thrombogenics announces agreement with Millipore for commercialization of stem cell technology

ThromboGenics NV has announced that it has completed a global license agreement with Millipore Corporation under which ThromboGenics will exclusively license its technology for production of the proprietary stem cell culture medium marketed by Millipore as RESGRO(x).

17 Apr 2007

Astrocytes may contribute to Lou Gehrig's disease

Two papers by Columbia and Harvard researchers report for the first time that astrocytes (the most abundant non-neuronal cells in the central nervous system), which carry a mutated gene known to cause some cases of amyotrophic lateral sclerosis (ALS/Lou Gehrig's disease), induce motor neuron death.

16 Apr 2007

Eating well still one of the best ways to prevent cancer and promote good health

We all know that eating fruits, vegetables and soy products provides essential nutrition for a healthy lifestyle, while obesity leads to the opposite.

16 Apr 2007

Study suggests reason for high incidence of cancer in the prostate

Cancer occurs more frequently in the prostates of men than in any organ other than the skin. While DNA damage caused by exposure to the sun is likely the cause of many skin cancers, the cause of prostate cancer remains largely unknown.

12 Apr 2007

Freedom from the egg holds much promise for new flu vaccines

An experimental flu vaccine made in insect cells – not in eggs, where flu vaccines currently available in the United States are grown – is safe and as effective as conventional vaccines in protecting people against the flu, according to results published in the April 11 issue of the Journal of the American Medical Association .

11 Apr 2007

Experimental flu vaccine produced using insect cells shows promise

An influenza vaccine produced with the use of insect cells appeared safe and produced an immunogenic response in healthy adults, suggesting promise as an alternative to using embryonated eggs for the development of influenza vaccine, according to a preliminary study in the April 11 issue of JAMA.

11 Apr 2007