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Unlocking H5N1 virus replication: an interview with Martin Blackledge

We were able to show that one small domain of the polymerase, the part that is essential for entry of a piece of the polymerase into the cell nucleus, changes its conformation to allow it to interact with the transporter protein than takes it into the nucleus.

3 Mar 2016

Barbara Ann Karmanos Cancer Institute recognized as one of America's Best Hospitals for Cancer Care

The Barbara Ann Karmanos Cancer Institute has received the 2016 Women's Choice Award as one of America's Best Hospitals for Cancer Care for the third consecutive year. Karmanos also received the award in 2011 and 2012, as well as 2014 and 2015.

12 Feb 2016

Understanding crucial role of 'healthy' brain in preventing memory failures linked to Alzheimer's disease

The mechanisms underlying the stability and plasticity of neural circuits in the hippocampus, the part of the brain responsible for spatial memory and the memory of everyday facts and events, has been a major focus of study in the field of neuroscience. Understanding precisely how a "healthy" brain stores and processes information is crucial to preventing and reversing the memory failures associated with Alzheimer's disease (AD), the most common form of late-life dementia.

2 Feb 2016

New study examines single 'transformer' proteins involved in cancer

A new study led by scientists at The Scripps Research Institute and St. Jude Children's Research Hospital shows how a protein involved in cancer twists and morphs into different structures.

22 Dec 2015

Study reveals molecular function of protein essential for replication of H5N1 flu virus

An international collaboration of scientists from the CEA, CNRS, University Joseph Fourier, the EMBL and the ILL has revealed the molecular function of a protein essential for replication of H5N1 influenza virus.

10 Dec 2015

Worldwide Protein Data Bank symposium focuses on multi-scale structural biology

The symposium titled with "Integrative Structural Biology with Hybrid Methods" is held focusing on the multi-scale structural biology, which aims to analyze structures of protein molecules and their assemblies, cellular machines, organelle, and even living cells and organisms by the hybrid methods, integrating many different technologies, such as chemical cross-links, MS spectrometry, FRET, Super-resolution microscopy, X-ray diffraction, NMR, and Computer modeling, in addition to Cryo-electron microscopy that has been attracting much attention these days.

10 Sep 2015

Barbara Ann Karmanos Cancer Institute named one of America's Best Hospitals for Cancer Care

The Barbara Ann Karmanos Cancer Institute has received the Women's Choice Award as one of America's Best Hospitals for Cancer Care for 2015. This award signifies Karmanos' commitment and passion towards providing an extraordinary healthcare experience for women and all patients.

9 Jun 2015

Rhinoplasty procedure more popular amongst men

Earlier this year, data was released by the American Society for Aesthetic Plastic Surgery (ASAPS) that detailed the rise in male plastic surgery procedures. The overall conclusion was that male procedures had risen 43 percent in the past 5 years.

2 Jun 2015

LaVision BioTec reports on the research work of the Milan-based Iannacone Laboratory to study virus responses using intravital microscopy

LaVison BioTec, developers of advanced microscopy solutions for the life sciences, report on the research of Dr Matteo Iannacone of the San Raffaele Scientific Institute in Milan where intravital microscopy is being applied to the study of host-viruses and associated immune responses.

5 May 2015

LaVision BioTec reports on the Beatson Institute for Cancer Research and their use of multiphoton microscopy to understand the behaviour of cells in cancer metastasis

LaVison BioTec, developers of advanced microscopy solutions for the life sciences, report on the research of Professor Kurt I Anderson and his groups' studies of cell migration in the context of cancer metastasis at the Beatson Institute for Cancer Research...

14 Apr 2015

BellBrook Labs announces launch of new Transcreener UDP TR-FRET Assay

BellBrook Labs, a leader in high throughput screening assays for drug discovery, announced the launch of a TR-FRET (time resolved Forster resonance energy transfer) version of the company's Transcreener UDP Assay, a high throughput screening assay for glycosyltransferases and other UDP-producing enzymes.

15 Jan 2015

Longer looks: the economics of infertility; placebos as treatment raises ethical dilemmas

About a decade ago, Medicaid programs were struggling to keep up with skyrocketing prescription drug costs. Between 1997 and 2002, drug spending in the program for low-income Americans grew by about 20 percent annually. ... Medicaid directors began looking for ways to tamp down on those costs. One of the most popular policies was something called "prior authorization" for a new wave of more expensive, anti-psychotic drugs ,... These policies, in a sense, worked: they helped rein in how much Medicaid spent filling prescriptions. But in another sense, they may not have worked at all: a growing body of research has begun questioning whether restricting drug spending may have just shifted costs elsewhere -; particularly, into the prison system (Sarah Kliff, 7/22).

25 Jul 2014

New Tel Aviv University study finds link between Alzheimer's and brain hyperactivity

Patients with Alzheimer's disease run a high risk of seizures. While the amyloid-beta protein involved in the development and progression of Alzheimer's seems the most likely cause for this neuronal hyperactivity, how and why this elevated activity takes place hasn't yet been explained - until now.

1 Jul 2014

Scientists decrypt interaction network of hepatitis C virus proteins in living human cells

Scientists at the Helmholtz Zentrum München have for the first time decrypted the interaction network of hepatitis C virus proteins in living human cells. Their findings will contribute to a better understanding of the mechanisms behind inflammatory liver disease caused by hepatitis C viruses and open up new avenues for therapy development.

9 May 2014

Cost of Hep C medicines vexing insurers

As health insurance companies reveal much anticipated first-quarter earnings, it's the unpredictable impact from the five-figure cost of new Hepatitis C treatments that are the subject of as much Wall Street worry as the Affordable Care Act.

22 Apr 2014

Viewpoints: Mcconnell, Wasserman Schultz, Barasso on Obamacare's 4th anniversary; defending surgeon general nominee

The promises that were made to sell Obamacare -; that it wouldn't disrupt people's previous health care arrangements and that premiums would go down -; are now being exposed for the cheap and deceptive sales pitch they were. It may be tempting for some to brush all this aside as standard politics.

25 Mar 2014

Uneven distribution of cellular organelles during cell division may enhance bacterial population's survival

Although a population of bacteria may be genetically identical, individual bacteria within that population can act in radically different ways.

3 Jan 2014

A High-speed, User-friendly Microplate Reader

An interview with Ville Hasslahti, discussing an advanced microplate reader that can cover a whole plate in 15 seconds or less.

From Hidex Oy 21 Nov 2013

Dems grow frustrated with Obamacare website, impact on broader law

Even some Obama allies are calling for major changes -- as well as someone's firing -- after the technically flawed rollout of the health law's online insurance marketplace. Democrats are also worried about what the problems could do to support for the broader law, and some are even calling for a delay to a mandate that Americans buy insurance.

25 Oct 2013

First Edition: October 24, 2013

Today's headlines include reports that the Obama administration plans to tweak the tax-penalty deadline for signing up for health insurance as well as previews of what might happen when the contractors who built the health law's online insurance marketplace testify today on Capitol Hill.

24 Oct 2013