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NEJM publishes results from two Jakafi Phase III studies on MF

The New England Journal of Medicine (NEJM) today published results from two Phase III studies (COMFORT-I and COMFORT-II) of Jakafi (ruxolitinib), a JAK1 and JAK2 inhibitor recently approved by the Food and Drug Administration (FDA) for the treatment of intermediate or high-risk myelofibrosis.

1 Mar 2012

Mantra-based meditation shows promise against age-associated cognitive impairment

Researchers at Thomas Jefferson University Hospital determined that mantra-based meditation can have a positive impact on emotional responses to stress, fatigue and anxiety in adults with memory impairment and memory loss.

29 Feb 2012

Tips to reduce potential sleep deprivation in children

For years, you've been through the loss of an hour in the spring and the gain of an hour in the fall as part of daylight saving time. With the upcoming time change slated for 2 a.m. Sunday, March 11, adults may be used to it, but children, including teenagers, may not be.

28 Feb 2012

SLU investigator aims to reduce chemotherapy-induced peripheral neuropathy

A Saint Louis University investigator noted for her pain research is working to reduce a painful chemotherapy side effect, thanks to a $126,500 grant from the Mayday Fund, an organization dedicated to alleviating the incidence, degree and consequence of human physical pain.

27 Feb 2012

Lung function, obstructive airway diseases linked with increased risk of heart failure

A large population-based study has found that lung function and obstructive airway diseases are strongly and independently associated with increased risk of heart failure. Importantly, say the investigators, this association was even evident in never-smokers and was still evident after adjustment for smoking status and number of years smoking. This, they add, indicates "that our results are not primarily confounded by smoking".

26 Feb 2012

Skin cancer drug may prolong survival in advanced cases: Study

Researchers say 132 patients in the U.S. and Australia who were given the drug vemurafenib gained several extra months of life. The study published in the New England Journal of Medicine found that those on the drug lived an average of 16 months, compared with nine months on conventional treatment.

26 Feb 2012

Study evaluates how environmental triggers might alter epigenetics of CFS

A University of Toronto Scarborough (UTSC) researcher is examining how environmental triggers might alter gene function in people with Chronic Fatigue Syndrome. The research could lead to better insights into the disease and eventually to new treatments.

24 Feb 2012

Ipsen, Active Biotech report data from tasquinimod Phase II study on CRPC

Active Biotech's and Ipsen's castrate resistant prostate cancer project, TASQ, will be presented at the 27th Annual EAU Congress held in Paris on 24-28 February 2012.

24 Feb 2012

Penn researchers produce first state-by-state sleep maps for the U.S.

Researchers at the Perelman School of Medicine at the University of Pennsylvania have put sleeplessness on the map - literally. The research team, analyzing nationwide data collected by the Centers for Disease Control and Prevention (CDC), has produced the first state-by-state sleep maps for the United States, revealing that residents of Southern states suffer from the most sleep disturbances and daytime fatigue, while residents on the West Coast report the least amount of problems.

24 Feb 2012

Vemurafenib nearly doubles survival for patients with metastatic melanoma

Investigators from Vanderbilt-Ingram Cancer Center (VICC) and 12 other centers in the United States and Australia have found that a new drug for patients with metastatic melanoma nearly doubled median overall survival.

23 Feb 2012

Gluten-free diet more of a fad than absolute necessity for many

Many people claim that gluten sensitivity is on the rise and consequently gluten-free products are more popular than ever. A study explores whether shunning gluten is really necessary and finds that in most cases it is not.

22 Feb 2012

Silent & atypical heart attacks more dangerous & fatal in young women

It is known that chest pain or discomfort is the most common heart attack symptom. In addition, fatigue, nausea, shortness of breath and pain or numbness in the jaw, arms or back can also signal a blocked artery cutting off vital oxygen and nutrients from the heart.

22 Feb 2012

March issue of BMJ's 'Sexually Transmitted Infections' focuses on HIV, health systems

Karen Grepin, assistant professor of global health policy at New York University's Robert F. Wagner Graduate School of Public Service, describes the March issue of BMJ's Sexually Transmitted Infections in this post in her "Global Health Blog."

22 Feb 2012

Referees' stress tolerance does not depend on specific physical condition

All referees feel stress on match days. However, contrary to what you might believe, a joint study by the Catholic University of Brasilia, A Coru-a University and James Cook University in Australia state that the level of stress is not linked to the physical condition of these referees, but to their nervous system. The researchers measured the activity of Spanish football referees on a normal day and on a match day.

22 Feb 2012

UMC Utrecht, DSM collaborate for Dyneema Purity fiber technology

DSM, a global leader in biomedical materials sciences, and University Medical Center Utrecht, a leading academic hospital with a renowned experimental facility unit for cardiothoracic interventions today announced that they have entered into a collaboration agreement.

22 Feb 2012

Corcept receives FDA approval for Korlym to treat endogenous Cushing's syndrome

Today, Korlym (mifepristone) was approved by the U.S. Food and Drug Administration to control high blood sugar levels (hyperglycemia) in adults with endogenous Cushing's syndrome.

18 Feb 2012

Strong spousal support helps cope with job stress

The growth of two-income families and increasing levels of job stress are two of the most significant work trends affecting American businesses and families in recent years. Having just one stressed-out spouse can harm couple's work and home lives - but what about when it's both?

17 Feb 2012

UC San Diego offers catheter ablation for patients with atrial fibrillation

UC San Diego Sulpizio Cardiovascular Center is now offering patients with atrial fibrillation the breakthrough benefits of heat energy, or radio frequency waves, to irreversibly alter heart tissue that triggers an abnormal heart rhythm or arrhythmia.

17 Feb 2012

Stress levels of unemployed people linked more to their surroundings

Stress levels of unemployed people are linked more to their surroundings than their age, gender, disposable income, and degree of deprivation, a study shows.

16 Feb 2012

Obesity may increase symptom severity and decrease QOL in patients with fibromyalgia

People with fibromyalgia can have difficulty getting a definitive diagnosis and finding an effective treatment plan. For many patients, the condition involves a confounding array of symptoms, including chronic pain, fatigue, sleep disturbance and mood disorders. One factor associated with fibromyalgia symptoms is a patient's weight, according to a Mayo Clinic study published on February 2012 in Arthritis Care & Research.

16 Feb 2012