Fatigue News and Research

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New findings from Micromet's blinatumomab phase 1 trial on DLBCL

New findings from a phase 1 trial presented yesterday at the 53rd Annual American Society of Hematology (ASH) Annual Meeting demonstrate Micromet's blinatumomab induces durable responses in patients with extensively pre-treated diffuse large B cell lymphoma.

12 Dec 2011

Many postmenopausal women quit breast cancer drugs early because of side effects

Why do so many postmenopausal women who are treated for estrogen-sensitive breast cancer quit using drugs that help prevent the disease from recurring? The first study to actually ask the women themselves -- as well as the largest, most scientifically rigorous study to examine the question -- reports 36 percent of women quit early because of the medications' side effects, which are more severe and widespread than previously known.

12 Dec 2011

Breast cancer hope with new drug and new combination regimens

last week at the San Antonio Breast Cancer Symposium, researchers announced encouraging results from studies of two cancer medications that appeared to keep breast cancer from advancing.

11 Dec 2011

Positive results from Puma's neratinib Phase II trials presented at CTRC-AACR San Antonio Breast Cancer Symposium

Puma Biotechnology, Inc., a development stage biopharmaceutical company, announced that results from ongoing Phase II clinical trials of Puma's investigational drug PB272 (neratinib) were presented at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium that is currently taking place in San Antonio, Texas.

9 Dec 2011

Positive results from Synta's Ganetespib Phase 2 trial on HER2-positive and triple negative mBC

Synta Pharmaceuticals Corp. - Ganetespib, a potent, second generation Hsp90 inhibitor, has demonstrated clinical activity in heavily pre-treated patients with HER2-positive and triple negative metastatic breast cancer according to Phase 2 clinical trial results presented by researchers from Memorial Sloan-Kettering Cancer Center at the San Antonio Breast Cancer Symposium.

9 Dec 2011

Sebelius overturns FDA on morning after pill access

The Health and Human Services Secretary Kathleen Sebelius this Wednesday has overturned the Food and Drug Administration's plan to remove the age limit on who can buy Teva Pharmaceutical Industries Ltd's Plan B One-Step pill – commonly known as the “morning after pill” without a prescription.

8 Dec 2011

Updated data from Novartis Afinitor plus everolimus Phase III study on advanced breast cancer

Updated results of a Phase III study of Afinitor (everolimus) tablets plus exemestane, a hormonal therapy, show everolimus provided additional time women with advanced breast cancer lived without their disease progressing.

8 Dec 2011

Donated permanent pacemakers safe and effective for Indian heart patients

Many heart patients in India are too poor to afford pacemakers. But a study has found that removing pacemakers from deceased Americans, resterilizing the devices and implanting them in Indian patients "is very safe and effective."

From Medtronic 7 Dec 2011

Testing athletes for concussions may induce mental fatigue

Testing athletes for concussions may induce mental fatigue in subjects whether or not they have a head injury, according to Penn State researchers.

7 Dec 2011

Move Day at U-M hospitals goes smoothly

Sunday's move from the now former U-M C.S. Mott Children's Hospital, the Von Voigtlander Women's Hospital and the Adult Bone Marrow Transplant Unit to the new facility began at 7:02 a.m. Sunday with a tiny patient - a baby moving from the Neonatal Intensive Care Unit.

6 Dec 2011

Breast cancer patients might experience prolonged fatigue years after chemotherapy

In a follow-up study, researchers at Moffitt Cancer Center and colleagues have found that patients who receive chemotherapy for breast cancer might experience prolonged fatigue years after their therapy.

6 Dec 2011

The head plays key role in tiring endurance performances

Researchers from the University of Zurich have now studied in detail what sportsmen and women know from experience: The head plays a key role in tiring endurance performances.

5 Dec 2011

Residents at neurosurgery training programs oppose new regulations limiting duty hours

Residents at U.S. neurosurgery training programs strongly oppose new regulations that further limit their duty hours, according to a survey study in the December issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

3 Dec 2011

Baby boomers more likely to develop HCV

Experts at Montefiore Medical Center urge the general public to be tested for the Hepatitis C virus, especially baby boomers, adults born between 1946-1964, who could be most at risk for this disease. Baby boomers are more likely to have been exposed to dangerous risk factors decades ago, such as sharing a drug needle, being tattooed or pierced with unsterilized tools or receiving a tainted blood transfusion.

2 Dec 2011

Treatments for lymphoma with no side effects

Larry Conrad went in for his annual physical on his 50th birthday. During his exam, his doctor found swollen lymph nodes in his armpits and groin. Conrad had a cough and said he'd lost weight because he 'felt full all the time'. His doctor ordered a series of tests, and Conrad was diagnosed with Non-Hodgkin's lymphoma, the most common type.

2 Dec 2011

NYU Langone establishes new LVAD Program for patients with advanced heart failure

The Cardiac & Vascular Institute at NYU Langone Medical Center has established its new LVAD Program. This surgical intervention program offers eligible, advanced heart failure patients implantation of the latest, lifesaving tool - a left ventricular assist device.

2 Dec 2011

Combination treatment improves progression-free survival in pancreatic neuroendocrine tumors

Combination treatment with everolimus, an inhibitor of the mammalian target rapamycin (mTOR), and octreotide has shown to improve progression-free survival for patients with advanced neuroendocrine tumors and a history of carcinoid syndrome, according to researchers at The University of Texas MD Anderson Cancer Center.

30 Nov 2011

CINJ experts available to discuss cancer-related fatigue

Between 70 and 100 percent of cancer patients receiving treatment suffer from fatigue related to their condition, according to the American Cancer Society, and up to one-half of all survivors have reported fatigue lasting months or even years after treatment. Fatigue can be one of the most distressing side effects of cancer treatment and can sometimes be overlooked by patients, caregivers and doctors.

28 Nov 2011

Migraines and depression risk: Study finds link

According to a new Canadian study, people who get attacks of migraine may be at a higher risk for developing clinical depression.

27 Nov 2011

No variation in mortality by timing of operation

The timing of surgical procedures—afternoon versus morning or Friday versus Monday—doesn't affect the risk of death after surgery, concludes a study in the December issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

24 Nov 2011

Fatigue News and Research

New findings from Micromet's blinatumomab phase 1 trial on DLBCL

Many postmenopausal women quit breast cancer drugs early because of side effects

Breast cancer hope with new drug and new combination regimens

Positive results from Puma's neratinib Phase II trials presented at CTRC-AACR San Antonio Breast Cancer Symposium

Positive results from Synta's Ganetespib Phase 2 trial on HER2-positive and triple negative mBC

Sebelius overturns FDA on morning after pill access

Updated data from Novartis Afinitor plus everolimus Phase III study on advanced breast cancer

Donated permanent pacemakers safe and effective for Indian heart patients

Testing athletes for concussions may induce mental fatigue

Move Day at U-M hospitals goes smoothly

Breast cancer patients might experience prolonged fatigue years after chemotherapy

The head plays key role in tiring endurance performances

Residents at neurosurgery training programs oppose new regulations limiting duty hours

Baby boomers more likely to develop HCV

Treatments for lymphoma with no side effects

NYU Langone establishes new LVAD Program for patients with advanced heart failure

Combination treatment improves progression-free survival in pancreatic neuroendocrine tumors

CINJ experts available to discuss cancer-related fatigue

Migraines and depression risk: Study finds link

No variation in mortality by timing of operation

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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