Fatigue News and Research

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Nplate reduces treatment failure and splenectomies in adults with chronic immune thrombocytopenia

Amgen Inc. today announced the publication of results from the first open-label study to compare Nplate® (romiplostim) treatment to standard of care therapies (SOC) in non-splenectomized adult patients with chronic immune thrombocytopenia (ITP). The study results, which were published today in the New England Journal of Medicine (NEJM), show that both the incidence of treatment failure and need for splenectomy were reduced among the Nplate-treated patients.

11 Nov 2010

Hemispherx Biopharma awarded grant for Ampligen, Alferon development programs

Hemispherx Biopharma, Inc. announced today grant awards totaling $488,958 from the U.S. Department of Treasury in support of its Ampligen and Alferon development programs.

10 Nov 2010

Aromatase inhibitors increase side effects in women undergoing breast cancer therapy

Women being treated for breast cancer with aromatase inhibitors may experience extremely low estrogen levels resulting in a wide variety of side effects that a typical postmenopausal woman without cancer may not experience.

10 Nov 2010

TONIX Pharmaceuticals announces Phase 2a study results of cyclobenzaprine in Fibromyalgia Syndrome

TONIX Pharmaceuticals (formerly known as Krele Pharmaceuticals), a specialty central nervous system (CNS) pharmaceutical company, announced results of a new analysis of a Phase 2a study, which previously demonstrated reduced pain, fatigue and tenderness in patients with Fibromyalgia Syndrome (FMS) following bedtime administration of very low dosage (VLD) cyclobenzaprine (CBP).

10 Nov 2010

Chronic fatigue syndrome associated with maladaptive personality features and personality disorders

This study suggests that chronic fatigue syndrome is associated with an increased prevalence of maladaptive personality features and personality disorders. This might be associated with being noncompliant with treatment suggestions, displaying unhealthy behavioral strategies and lacking a stable social environment.

8 Nov 2010

Tai Chi benefits individuals with arthritis

In the largest study to date of the Arthritis Foundation's Tai Chi program, participants showed improvement in pain, fatigue, stiffness and sense of well-being.

8 Nov 2010

Hydroxychloroquine may reduce cardiac neonatal lupus in subsequent pregnancies: Research

Women with anti-SSA/Ro antibodies and a previous child who has heart block a condition where the electrical signal that makes the heart beat is damaged may potentially decrease their risk of delivering another child with life threatening heart disease by taking hydroxychloroquine (Plaquenil), according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Atlanta.

8 Nov 2010

People with SLE more likely to develop hematologic malignancies

People with systemic lupus erythematosus are 1.15 times as likely to develop cancer as the general population and more than 2.5 times as likely to develop hematologic malignancies, such as lymphoma and leukemia, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Atlanta.

8 Nov 2010

Chronic lower back pain may be linked to axial spondyloarthritis: Research

Chronic lower back pain may be linked to a recently defined form of inflammatory arthritis known as axial spondyloarthritis, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Atlanta.

8 Nov 2010

SGN-35 drug reduces tumor growth in Hodgkin's lymphoma

An experimental drug for Hodgkin's lymphoma, studied at the University of Alabama at Birmingham, showed beneficial effects in stopping tumor growth with moderate side-effects, according to findings published Thursday in the New England Journal of Medicine.

8 Nov 2010

FDA approves Cymbalta for treatment of chronic musculoskeletal pain

The U.S. Food and Drug Administration today approved Cymbalta (duloxetine hydrochloride) to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain. Cymbalta was first used to treat major depressive disorder in 2004.

8 Nov 2010

AVEO third quarter total collaboration revenues increase to $6.2 million

AVEO Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering, developing and commercializing cancer therapeutics, today announced updated financial guidance and third quarter financial results, as well as recent developments.

4 Nov 2010

New England Journal of Medicine publishes brentuximab vedotin Phase I clinical trial data

Seattle Genetics, Inc. and Millennium: The Takeda Oncology Company, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, today announced that data from a phase I single-agent clinical trial of brentuximab vedotin (SGN-35) will be published in the November 4, 2010 issue of the New England Journal of Medicine.

4 Nov 2010

Loyola University surgeon uses new technique to reopen blockages in coronary arteries

In some heart patients, coronary arteries become so clogged that they are difficult or impossible to reopen with conventional balloon angioplasties. Dr. John Lopez of Loyola University Health System is using a new angioplasty technique to reopen these tough blockages by going through the "back door." The technique, called retrograde recanalization, was developed in Japan and is beginning to catch on in centers with advanced expertise in cardiac catheterization.

4 Nov 2010

Single injection of morphine to fight persistent pain reduces testosterone level: Research

A single injection of morphine to fight persistent pain in male rats is able to strongly reduce the hormone testosterone in the brain and plasma, according to a new paper published in Molecular Pain.

4 Nov 2010

Workers unwilling to disclose work related stress: Survey

According to findings from a survey by mental health charity Mind, millions of British workers have lied to their bosses about taking sick leave when they feel overwhelmed by stress. The survey showed that one in five workers (19%) have taken stress-induced sick leave, but virtually all of them (93%) say they have lied to their boss about the real reason for not turning up. The usual reasons cited are stomach upsets, housing problems or even have a sick relative, rather than admitting the truth.

3 Nov 2010

Working at night and in rotating shifts increase risk of work injury

Canadians who work night and rotating shifts are almost twice as likely to be injured on the job than those working regular day shifts, according to a study by researchers at the University of British Columbia.

3 Nov 2010

Combining telaprevir regimen with standard therapy improves SVR rate in hepatitis C

For patients with the most common form of hepatitis C being treated for the first time, the addition of an investigational hepatitis C-specific protease inhibitor called telaprevir to the current standard therapy markedly improved their sustained viral response (SVR or viral cure) rate.

3 Nov 2010

GSK's Revolade receives Japanese approval for treatment of chronic ITP

Ligand Pharmaceuticals Incorporated today announced its partner GlaxoSmithKline was granted approval from the Japanese Ministry of Health, Labour and Welfare for Revolade® (eltrombopag) for the treatment of the blood disorder, chronic idiopathic thrombocytopenic purpura (ITP).

2 Nov 2010

CareChex releases new study on University Hospital Care in the U.S.

CareChex, a division of The Delta Group specializing in rating the quality of hospital and physician care, today released a new study, An Assessment of the Quality of University Hospital Care in the U.S., that investigates whether or not university hospitals outperform other hospitals on objective measures of quality.

2 Nov 2010

Fatigue News and Research

Nplate reduces treatment failure and splenectomies in adults with chronic immune thrombocytopenia

Hemispherx Biopharma awarded grant for Ampligen, Alferon development programs

Aromatase inhibitors increase side effects in women undergoing breast cancer therapy

TONIX Pharmaceuticals announces Phase 2a study results of cyclobenzaprine in Fibromyalgia Syndrome

Chronic fatigue syndrome associated with maladaptive personality features and personality disorders

Tai Chi benefits individuals with arthritis

Hydroxychloroquine may reduce cardiac neonatal lupus in subsequent pregnancies: Research

People with SLE more likely to develop hematologic malignancies

Chronic lower back pain may be linked to axial spondyloarthritis: Research

SGN-35 drug reduces tumor growth in Hodgkin's lymphoma

FDA approves Cymbalta for treatment of chronic musculoskeletal pain

AVEO third quarter total collaboration revenues increase to $6.2 million

New England Journal of Medicine publishes brentuximab vedotin Phase I clinical trial data

Loyola University surgeon uses new technique to reopen blockages in coronary arteries

Single injection of morphine to fight persistent pain reduces testosterone level: Research

Workers unwilling to disclose work related stress: Survey

Working at night and in rotating shifts increase risk of work injury

Combining telaprevir regimen with standard therapy improves SVR rate in hepatitis C

GSK's Revolade receives Japanese approval for treatment of chronic ITP

CareChex releases new study on University Hospital Care in the U.S.

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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