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Scientists use NMR technology to improve protein purification in drug development

The purification of drug components is a large hurdle facing modern drug development. This is particularly true of drugs that utilize proteins, which are notoriously difficult to separate from other potentially deadly impurities. Scientists within the Center for Biotechnology and Interdisciplinary Studies (CBIS) at Rensselaer Polytechnic Institute are using nuclear magnetic resonance (NMR) to understand and improve an important protein purification process.

30 Sep 2010

China-Biotics files two new patent applications

China-Biotics, Inc., the leading developer, manufacturer and distributor of probiotics products in China, today announced that it has submitted two new patent applications to the State Bureau of Intellect Property.

17 Sep 2010

Lactic acid fermentation reduces acrylamide formation during production of potatoes and coffee

A small research-based Norwegian company has developed a method to reduce the formation of the carcinogenic compound acrylamide during industrial production of potatoes and coffee. International food giants are paying attention.

9 Sep 2010

DSM, PolyTherics enter agreement for HiPEG IFN alpha-2a product development

DSM BioSolutions, DSM's microbial fermentation CMO business unit and PolyTherics Limited an innovator in precision engineering of proteins, today announced that they have entered into an agreement for the process development and manufacture of PolyTherics' lead biobetter product, HiPEG IFN alpha-2a.

7 Sep 2010

Biopharmaceutical firms take steps to create greener working environments

Biopharmaceutical firms and other life science organizations are taking definitive steps toward creating greener working environments and developing more sustainable operations, reports Genetic Engineering & Biotechnology News (GEN).

3 Sep 2010

Study finds source of tetracycline from bone analysis of Nubians

A chemical analysis of the bones of ancient Nubians shows that they were regularly consuming tetracycline, most likely in their beer. The finding is the strongest evidence yet that the art of making antibiotics, which officially dates to the discovery of penicillin in 1928, was common practice nearly 2,000 years ago.

3 Sep 2010

BiondVax receives 2010 European Influenza Vaccines Technology Innovation Award

Frost & Sullivan is pleased to announce the award of its prestigious 2010 European Influenza Vaccines Technology Innovation Award to BiondVax Pharmaceuticals for their breakthrough work on a universal influenza vaccine. This vaccine, the Multimeric-001, is designed to provide multi-season and multi-strain protection against most influenza virus strains, including both seasonal and pandemic strains, and has the potential to eliminate the need for annual flu vaccination. BiondVax is entering Phase II clinical trials for the development of the Multimeric-001 universal influenza vaccine.

28 Jul 2010

FDA confirms GRAS status for Ajinomoto's AjiGRAS-Leucine

Ajinomoto AminoScience LLC (AAS) today announced that it has confirmed GRAS (Generally Recognized As Safe) status of its AjiGRAS-Leucine, meeting the safety standards demanded by the US Food and Drug Administration (FDA). As the only formulation of Leucine currently with FDA acknowledged GRAS status, Ajinomoto's AjiGRAS-Leucine is the first amino acid to be allowed as an ingredient for use in conventional foods like non-milk and milk based meal replacements, sports and isotonic beverages, vitamin enhanced waters, and meal replacement bars, at levels of 0.5 to 3 grams per serving.

16 Jul 2010

China-Biotics fourth-quarter revenues up 64.4% to $25.5 million

China-Biotics, Inc., a leading developer, manufacturer and distributor of probiotics products in China, today reported its financial results for the fourth quarter and the fiscal year ended March 31, 2010.

11 Jun 2010

DSM commences cGMP-manufacturing of Novacta's C. difficile compound

DSM BioSolutions today announced that it has entered into an agreement with Novacta Biosystems Limited, Welwyn Garden City, UK, for the process development and cGMP production of its C. difficile molecule, a new class of lantibiotic compounds.

9 Jun 2010

Isobionics finalizes fermentation process for production of natural Valencene Pure

Isobionics has finalized the development of a breakthrough fermentation process for production of its natural Valencene Pure. This product, which is an aroma substance for the food, beverage, flavor and fragrance industry, is now available on a commercial scale. Compared with conventional valencene, which is produced from oranges, it offers the advantage of high purity and constant quality.

7 Jun 2010

New symbiotic starter culture investigated for production of original yogurt

Yogurt production is traditional branch in our food industry. Yogurt is a fermented milk product that contains the characteristic bacterial cultures Lactobacillus bulgaricus and Streptococcus thermophilus. One of them is invented and used for the first time in our country and that's why it is named after Bulgaria.

5 Jun 2010

PCA-Rx represents next generation of chelation technology for ASD patients

According to the Center for Disease Control, autism has risen to an epidemic rate of 1 in 100 in the U.S., up from 1 in 150 in 2007. While controversy looms regarding its cause, many parents of autistic children believe a correlation exists with toxin accumulation. To give autism spectrum disorder sufferers a natural alternative to chelation therapy, Maxam Nutraceutics has introduced PCA-Rx.

28 May 2010

Rice University researcher receives 2010 Glycerine Innovation Award

Escherichia coli - E. coli for short - is often identified as a bacterium that contributes to foodborne illness. But research led by a Rice University scientist has discovered ways to use a safe, non-pathogenic E. coli to convert glycerine into high value fuels and chemicals.

21 May 2010

Microbiologists identify potential target in cattle to prevent E. coli strain

Microbiologists at UT Southwestern Medical Center, working with the Department of Agriculture, have identified a potential target in cattle that could be exploited to help prevent outbreaks of food-borne illnesses caused by a nasty strain of Escherichia coli.

13 May 2010

BioGenes study documents insufficient sensitivity of ELISA-based generic HCP assay

BioGenes GmbH, a supplier of GMP-compliant immunoassays and antibodies, completed a study that documents the insufficient sensitivity of an ELISA-based generic host cell protein assay. The results confirm the observation of several contract manufacturers that generic HCP assays are only of limited use for detection of HCPs during manufacturing processes.

12 May 2010

Whole grain barley products with low glycemic response provide favourable metabolic benefits

Evidence from observational studies indicates that diets rich in whole grain reduce risk of obesity and other diseases related to the metabolic syndrome e.g. type 2 diabetes and cardio-vascular disease. The mechanisms involved are only partially elucidated. Work within HEALTHGRAIN has revealed novel insights regarding some potential mechanisms.

6 May 2010

Diets rich in whole grain reduce risk of obesity and other diseases related to metabolic syndrome

5 May 2010

Enzyme technology developed to improve quality, safety and nutritional attributes of oat based foods

Oats is a highly nutritious cereal, which can be tolerated by large number of celiac patients. A range of commercial oat flours as well as specific oat flours produced from single varieties have been evaluated for their suitability for bread-baking. Enzyme technology, bioprocessing as well as high-pressure processing technology have been successfully applied to improve the quality, safety and nutritional attributes of oat based foods.

5 May 2010

Targeted antibiotics provide safe, long-lasting improvement for IBS patients, says study

A targeted antibiotic provides effective and long-lasting relief of Irritable Bowel Syndrome symptoms, according to the results of two multisite Phase III clinical trials designed by Cedars-Sinai researchers. Rifaximin is the first drug treatment for IBS that relieves symptoms while it's being administered and continues to benefit patients after they stop taking the drug.

5 May 2010

Fermentation News and Research

Scientists use NMR technology to improve protein purification in drug development

China-Biotics files two new patent applications

Lactic acid fermentation reduces acrylamide formation during production of potatoes and coffee

DSM, PolyTherics enter agreement for HiPEG IFN alpha-2a product development

Biopharmaceutical firms take steps to create greener working environments

Study finds source of tetracycline from bone analysis of Nubians

BiondVax receives 2010 European Influenza Vaccines Technology Innovation Award

FDA confirms GRAS status for Ajinomoto's AjiGRAS-Leucine

China-Biotics fourth-quarter revenues up 64.4% to $25.5 million

DSM commences cGMP-manufacturing of Novacta's C. difficile compound

Isobionics finalizes fermentation process for production of natural Valencene Pure

New symbiotic starter culture investigated for production of original yogurt

PCA-Rx represents next generation of chelation technology for ASD patients

Rice University researcher receives 2010 Glycerine Innovation Award

Microbiologists identify potential target in cattle to prevent E. coli strain

BioGenes study documents insufficient sensitivity of ELISA-based generic HCP assay

Whole grain barley products with low glycemic response provide favourable metabolic benefits

Diets rich in whole grain reduce risk of obesity and other diseases related to metabolic syndrome

Enzyme technology developed to improve quality, safety and nutritional attributes of oat based foods

Targeted antibiotics provide safe, long-lasting improvement for IBS patients, says study

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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