Fibroblast News and Research

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Fibroblasts are connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

AI reveals hidden rules of cell neighborhoods in cancer

Researchers from Children's Hospital of Philadelphia have developed a new AI-powered algorithm to help understand how different cells organize themselves into particular tissues and communicate with one another.

8 Jan 2024

New study brings us closer to growing replacement lungs for patients

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. It is marked by lung damage that is lasting and incurable, leaving lung transplantation as the only viable treatment option.

5 Jan 2024

68Ga-FAPI PET imaging superior to existing methods for detecting pancreatic cancer

PET imaging with 68Ga-FAPI can more effectively detect and stage pancreatic cancer as compared with 18F-FDG imaging or contrast-enhanced CT, according to new research published in the December issue of The Journal of Nuclear Medicine.

2 Jan 2024

Insilico Medicine develops new AI-generated FGFR2/3 inhibitor for tissue-agnostic solid tumors

Insilico Medicine ("Insilico"), a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM8001, a novel molecule targeting FGFR2/3 for the treatment of tissue-agnostic solid tumors bringing the total number of PCCs nominated in 2023 to six.

28 Dec 2023

Understanding the link between primary cilia, biological clock and wound healing

Nearly every organism on Earth follows a natural circadian rhythm that is coded by your cell's clock genes, which do exactly as you suspect from the name: regulate your body's rhythm on a 24-hour basis.

21 Dec 2023

Deep learning unlocks new antibiotic classes, revolutionizing the fight against resistance

A Nature journal study employs deep learning to analyze chemical sub-structures, leading to the discovery of new structural classes of antibiotics, showcasing the potential of AI in accelerating antibiotic development.

20 Dec 2023

New technique reveals hidden communication network in tumors

A study conducted by pre-PhD researcher Pablo S. Valera and recently published in PNAS demonstrates the potential of surface-enhanced Raman spectroscopy (SERS) to explore metabolites secreted by cancer cells in cancer research.

18 Dec 2023

QUT scientists discover promising treatment for fatal endometrial cancer

QUT scientists have discovered a promising new therapy for a deadly type of endometrial cancer that has a poor prognosis if the cancer spreads or returns after initial treatment, a plight that affects 15-20 per cent of endometrial cancer patients.

15 Dec 2023

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

UVA atlas unveils cellular blueprint of atherosclerosis

University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heart attacks, strokes and coronary artery disease.

12 Dec 2023

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Study demonstrates that inhibiting stromal class I histone deacetylases (HDACs) can effectively slow down pancreatic cancer progression, shedding light on a new therapeutic approach targeting the tumor microenvironment.

10 Dec 2023

Understanding why healthy cells help cancer cells to evade treatment

Chemotherapy becomes less effective because healthy cells push cancer cells to grow more slowly, according to two studies from researchers at UCL and Yale.

9 Dec 2023

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Pancreatic cancer is one of the deadliest cancers-;only about one in eight patients survives five years after diagnosis.

6 Dec 2023

Simple bean diet intervention demonstrates significant prebiotic effects

The impact of incorporating canned navy beans into the regular diet for eight weeks.

5 Dec 2023

Temporal morphogen-driven neural induction spurs growth of expanded brain organoids with enhanced neuroepithelium formation

Researchers examinea the effects of temporal morphogen gradient during neural induction on the formation of brain organoids.

4 Dec 2023

Genetic mutation in OXR1 gene linked to brain development issues

Study investigates the effects of a loss-of-function mutation in the OXR1 gene on neurodevelopment and cellular functions in the human brain. The research shows that OXR1 deficiency impairs neural differentiation, increases sensitivity to oxidative stress, and alters histone methylation, impacting brain development and potentially contributing to neurological disorders.

27 Nov 2023

Fibroblast News and Research

Further Reading

AI reveals hidden rules of cell neighborhoods in cancer

New study brings us closer to growing replacement lungs for patients

68Ga-FAPI PET imaging superior to existing methods for detecting pancreatic cancer

Insilico Medicine develops new AI-generated FGFR2/3 inhibitor for tissue-agnostic solid tumors

Understanding the link between primary cilia, biological clock and wound healing

Deep learning unlocks new antibiotic classes, revolutionizing the fight against resistance

New technique reveals hidden communication network in tumors

QUT scientists discover promising treatment for fatal endometrial cancer

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

UVA atlas unveils cellular blueprint of atherosclerosis

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Understanding why healthy cells help cancer cells to evade treatment

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Simple bean diet intervention demonstrates significant prebiotic effects

Temporal morphogen-driven neural induction spurs growth of expanded brain organoids with enhanced neuroepithelium formation

Genetic mutation in OXR1 gene linked to brain development issues

Exploring the impact of soy isoflavones in prostate cancer therapy

Pitt researcher receives $1.95 million grant to study cell communication

Amalus Therapeutics develops innovative approach for treating patients with cancer or fibrotic diseases

Study sheds light on specific variants responsible for rare and serious disorder

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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