Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Autopsy study provides new insights into yellow fever's impact on the heart

To fill gaps in knowledge of yellow fever (YF), a group of researchers in Brazil affiliated with the Department of Pathology at the University of São Paulo's Medical School (FM-USP), Hospital das Clínicas (HC, the hospital complex run by FM-USP), the Heart Institute (InCor, linked to HC) and Emílio Ribas Institute of Infectious Diseases (IIER) decided to study the pathogenesis of YF-associated heart injury.

19 Dec 2023

“Forever chemicals” could contribute to cancer metastasis in living organisms

In a new study by researchers at the Yale School of Public Health, two "forever chemicals" spurred cancer cells in the lab to migrate to new positions, an indication that the chemicals could contribute to cancer metastasis in living organisms.

18 Dec 2023

Two proteins in the blood could predict dengue severity

Scientists and clinicians at Nanyang Technological University, Singapore (NTU Singapore) and the National Centre for Infectious Diseases (NCID) have identified two compounds - sST2 and suPAR - in the blood of dengue patients that could determine if a patient is at risk of severe dengue in the early phases of the disease.

18 Dec 2023

Study suggests iron accumulation plays a central role in senescence and fibrosis

Researchers investigated the association between cellular damage, iron buildup, senescence, and fibrosis.

18 Dec 2023

Experimental drug paired with a standard-care medication offers hope for kidney disease patients

In a clinical trial of patients with chronic kidney disease, an experimental drug significantly reduced albuminuria -; albumin in urine, a sign of kidney damage -; for 50% of participants.

15 Dec 2023

Study establishes iron accumulation as a driver of pathological senescence and fibrosis

Fibrosis is associated with various chronic and life-threatening conditions, including pulmonary fibrosis, liver cirrhosis, kidney disease, and cardiovascular diseases, among others.

14 Dec 2023

Novel stem cell treatment could revolutionize liver disease management

Mortality related to end stage liver disease is ranked as the 12th most common cause of death in the U.S. Liver transplantation remains the only treatment for end stage liver disease, but there is a critical shortage of organ donors, necessitating a dire need for new forms of treatment.

7 Dec 2023

New insights into the cellular programs that promote resolution of inflammation during aging

Aging is associated with chronic, nonresolving inflammation, or "inflammaging," that can lead to tissue dysfunction.

6 Dec 2023

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Pancreatic cancer is one of the deadliest cancers-;only about one in eight patients survives five years after diagnosis.

6 Dec 2023

Revolutionary self-folding nanoscale MRI agent sharpens cancer imaging

Study introduces a novel self-folding nanoscale contrast agent for MRI, enhancing tumor visualization with lower gadolinium loads and reduced risk of adverse effects.

5 Dec 2023

Insilico Medicine hosts three webinars to unveil latest technology breakthroughs

Insilico Medicine ("Insilico"), an artificial intelligence (AI)-driven, clinical stage biotechnology company and leader in AI drug discovery platform technology, is hosting three webinars unveiling its latest technology breakthroughs Nov. 28-30, 2023.

29 Nov 2023

Wayne State professor wins $2.65 million NIH award to develop novel filtration platform for insulin administration

A Wayne State University College of Engineering professor has received a $2.65 million award from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health to develop a novel filtration platform to improve an advanced drug delivery device to optimize diabetes insulin treatments.

28 Nov 2023

Radiation therapy could improve cardiac function in heart failure

Cardiologists and radiation oncologists at Washington University School of Medicine in St. Louis pioneered the use of radiation therapy -; a strategy typically used against cancer -; to treat patients with a life-threatening abnormal heart rhythm called ventricular tachycardia.

28 Nov 2023

Synthetic biologists develop versatile platform for targeted drug delivery

In recent years, cell and gene therapies have shown significant promise for treating cancer, cystic fibrosis, diabetes, heart disease, HIV/AIDS and other difficult-to-treat diseases.

27 Nov 2023

Feasting for immunity: Study highlights foods that bolster your body's defenses

Study reviews how certain foods, including fruits, vegetables, spices, and animal products, bolster the immune system. It details the immune-boosting properties of various foods and underscores the importance of a nutritious diet in disease prevention and management.

26 Nov 2023

Study identifies key markers for early detection of fatty liver disease in obese and non-obese individuals

In a study published in 'Scientific Reports', researchers found that insulin resistance markers TyG-BMI and HOMA-IR effectively predict non-alcoholic fatty liver disease (NAFLD) risks in non-obese and obese individuals without diabetes, respectively. These findings suggest new, non-invasive methods for early NAFLD detection, particularly in atypical non-obese cases.

26 Nov 2023

Scientists create living phlegm replica to study cystic fibrosis infections

Scientists have engineered a living material resembling human phlegm, which will help them to better understand how a certain kind of infection develops on the lungs of patients with cystic fibrosis.

21 Nov 2023

Pitt researcher receives $1.95 million grant to study cell communication

Day by day, we communicate with our office colleagues to accomplish tasks that are necessary to function.

21 Nov 2023

Amalus Therapeutics develops innovative approach for treating patients with cancer or fibrotic diseases

Ghent University and the booming Ghent biotech landscape welcome a brand new spin-off: Amalus Therapeutics is developing a new class of drugs that selectively target corrupt fibroblast cells.

20 Nov 2023

MHRA extends the license of two cystic fibrosis drugs for children aged two to five years old

The Medicines and Healthcare products Regulatory Agency (MHRA) has today (15 November 2023) extended the licence of the cystic fibrosis medicines Kaftrio (ivacaftor, tezacaftor and elexacaftor) and Kalydeco (ivacaftor) for children aged two to five years old.

20 Nov 2023

Fibrosis News and Research

Further Reading

Autopsy study provides new insights into yellow fever's impact on the heart

“Forever chemicals” could contribute to cancer metastasis in living organisms

Two proteins in the blood could predict dengue severity

Study suggests iron accumulation plays a central role in senescence and fibrosis

Experimental drug paired with a standard-care medication offers hope for kidney disease patients

Study establishes iron accumulation as a driver of pathological senescence and fibrosis

Novel stem cell treatment could revolutionize liver disease management

New insights into the cellular programs that promote resolution of inflammation during aging

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Revolutionary self-folding nanoscale MRI agent sharpens cancer imaging

Insilico Medicine hosts three webinars to unveil latest technology breakthroughs

Wayne State professor wins $2.65 million NIH award to develop novel filtration platform for insulin administration

Radiation therapy could improve cardiac function in heart failure

Synthetic biologists develop versatile platform for targeted drug delivery

Feasting for immunity: Study highlights foods that bolster your body's defenses

Study identifies key markers for early detection of fatty liver disease in obese and non-obese individuals

Scientists create living phlegm replica to study cystic fibrosis infections

Pitt researcher receives $1.95 million grant to study cell communication

Amalus Therapeutics develops innovative approach for treating patients with cancer or fibrotic diseases

MHRA extends the license of two cystic fibrosis drugs for children aged two to five years old

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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