Fluorescence News and Research

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Researchers create new family of fluorescent probes called hydrocyanines to detect reactive oxygen species in vivo

Researchers have created a new family of fluorescent probes called hydrocyanines that can be used to detect and measure the presence of reactive oxygen species.

15 Dec 2008

New imaging technique allows simultaneous tracking of gene expression and movement

Flies expressing green fluorescent protein (GFP) in their retina cells or other tissues can be tracked by specially modified video cameras, creating a real time computer record of movement and gene expression.

15 Dec 2008

Breakthrough in Alzheimer's disease screening

Australian scientists at CSIRO (Commonwealth Scientific and Industrial Research Organisation), have developed a new system to screen for compounds that can inhibit one of the processes that takes place during the progression of Alzheimer's disease.

15 Dec 2008

Mouse model shows blood stem cells in action

Over a period of five years, scientists at the Johannes Gutenberg University Mainz have managed to create a genetically modified mouse in which the activity of the blood stem cells can be tracked.

15 Dec 2008

Carbon nanotube sensors for cancer drugs

MIT engineers have developed carbon nanotubes into sensors for cancer drugs and other DNA-damaging agents inside living cells.

14 Dec 2008

Researchers capture never before seen undulations of "dancing chromosomes"

The rhythm of life may beat far deeper than anyone previously thought. And it may gyrate and pulse in a way that rivals the sensuous choreography of "Dirty Dancing."

12 Dec 2008

Mathematical models of adaptive immunity

More than five million people die every year from infectious diseases, despite the availability of numerous antibiotics and vaccines. The discovery of penicillin to treat bacterial infections, along with the development of vaccines for previously incurable virus diseases such as polio and smallpox, achieved great reductions in mortality during the mid-20th century.

11 Dec 2008

Studies on imaging and tracking transplanted cells

Successfully monitoring the distribution and fate of transplanted stem cells through imaging and subsequent tracking would aid clinicians in their ability to evaluate the efficacy of transplanted cells.

10 Dec 2008

Scans show immune cells intercepting parasites

Researchers may have identified one of the body's earliest responses to a group of parasites that causes illness in developing nations.

10 Dec 2008

Early photon tomography provides clearer picture of tumors in living animals

Fluorescent molecules - i.e. substances which can be stimulated to emit light - are extremely valuable tools in biological research and medical diagnosis.

10 Dec 2008

Researchers visualize how cells coordinate their movements

Using novel imaging, labeling, and data-analysis techniques, scientists from the California Institute of Technology (Caltech) have been able to visualize, for the first time, large numbers of cells moving en masse during some of the earliest stages of embryonic development.

10 Dec 2008

Aperio Technologies receives another patent for TDI arrays in microscope slide scanners

Aperio Technologies, Inc., (Aperio), a global leader in digital pathology for the healthcare and life sciences industry, announced today that the United States Patent and Trademark Office has issued the company patent No. 7,457,446 entitled "Fully Automatic Rapid Microscope Slide Scanner."

10 Dec 2008

Glowing imaging compound allows detection of viable cancer cells in mice

Researchers have developed a new type of imaging compound that allows them to visualize viable breast cancer cells that have spread to the lungs in mice.

8 Dec 2008

Hematopoietic stem cells found to reproduce more slowly than expected

Investigators from Massachusetts General Hospital (MGH) have found a subpopulation of hematopoietic stem cells, the source of all blood and immune system cells, that reproduce much more slowly than previously anticipated.

8 Dec 2008

Prototype blood scanner detects even faint indicators of cancer

A team led by Stanford researchers has developed a prototype blood scanner that can find cancer markers in the bloodstream in early stages of the disease, potentially allowing for earlier treatment and dramatically improved chances of survival.

3 Dec 2008

New technique provides closer look at DNA and mRNA

In a study in the advance online edition of Nature Structural and Molecular Biology, researchers from Albert Einstein College of Medicine describe a technique for looking more precisely at a fundamental step of a cell's life - a gene, DNA, being read into a message, mRNA.

3 Dec 2008

Lab on a microfluidic chip for the GP's surgery

If doctors were able to conduct efficient genetic analysis at the point of care, using inexpensive, portable equipment, it would revolutionise disease detection and treatment. European researchers are close to enabling this revolution.

2 Dec 2008

New cell analysis platform developed - commercial partners sought

Sandia National Laboratories is seeking commercial partners to license or contribute to the continued development of a new lab-on-a-chip platform for high-throughput manipulation and interrogation of individual cells, one that enables quantitative analysis of cellular behaviors with unprecedented speed, resolution, sensitivity, and multiplexing.

1 Dec 2008