Fluorescence Microscopy News and Research

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Fluorescence microscopy is an imaging technique used to examine cells and their internal components. Specific cellular components can be labeled with fluorophores.

Research reveals how Zika virus infection spurs fetal demise

A powerful antiviral protein may act as a checkpoint for keeping or ending a pregnancy.

5 Jan 2018

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

When a coronary artery is obstructed by atheroma, blood flow is depressed or even arrested. This causes hypoxia of cardiac cells associated with the deprivation of nutrients. In clinic, the first objective is to restore blood flow. However, this is associated with a burst in oxidation of cellular proteins and lipids. This oxidation enhances cell death and participates to the so-called reperfusion injury.

From Logos Biosystems 18 Dec 2017

Researchers release open-source dataset offering instructions to build smartphone microscope

Add one more thing to the list of tasks your smartphone can perform. University of Houston researchers have released an open-source dataset offering instructions to people interested in building their own smartphone microscope.

30 Nov 2017

Natural-shaped plastic nanoparticles could improve delivery of toxic drugs to tumors

UNSW Sydney scientists have developed a way to control the shape of polymer molecules so they self-assemble into non-spherical nanoparticles - an advance that could improve the delivery of toxic drugs to tumors.

1 Nov 2017

Researchers identify link between circadian rhythm disturbance and brain dysfunction

Researchers at Okayama University describe in the Journal of Neuroscience that a certain protein known to play a major role in circadian rhythmicity — humans’ intrinsic 24-hour biological cycle — is also key to proper brain functioning.

31 Oct 2017

NIH launches major effort to discover, catalog the brain's ‘parts list’

The National Institutes of Health has launched a major effort to discover and catalog the brain's "parts list." The NIH's Brain Research through Advancing Innovative Neurotechnologies® Initiative Cell Census Network aims to provide researchers with a comprehensive reference of the diverse cell types in human, monkey, and mouse brain.

24 Oct 2017

Measuring biological samples using SNAP

My group is interested in host pathogen interaction and we mainly focus on how bacteria enter cells. In essence, the idea is that if you can prevent bacteria from entering cells, then you will prevent illness.

From Bruker Nano Surfaces and Metrology 24 Oct 2017

New way of tagging exosomes could have long term benefits in treatment of life-threatening conditions

The development of a new technique for labelling the body’s own transporters – exosomes - could have long term benefits in the treatment of life-threatening medical conditions, including cancer.

28 Sep 2017

New way of tagging exosomes could have long term benefits in treatment of life-threatening conditions

The development of a new technique for labeling the body’s own transporters – exosomes - could have long term benefits in the treatment of life-threatening medical conditions, including cancer.

28 Sep 2017

Optical Microscopy Resolution Revolution

I will talk about the simple but fundamental idea that allowed breaking the diffraction barrier in fluorescence microscopy as well as about MINFLUX nanoscopy, the latest development in the field that for the first time provides true molecular resolution with visible light and standard objective lenses.

From Pittcon 12 Sep 2017

Zirconia-doped ceria nanoparticles can act as effective antioxidants in sepsis treatment

During sepsis, cells are swamped with reactive oxygen species generated in an aberrant response of the immune system to a local infection.

6 Jul 2017

Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

The design of tailored peptide-polymer conjugates as drug-specific formulation additives offers access to next generation precision additives that can render problematic small organic drugs water-soluble and improve bioavailability.

30 Jun 2017

Francis Crick Institute selects Livecyte cell analysis system from Phasefocus

Phasefocus provides a range of products and services based on its proprietary Ptychographic Quantitative Phase Imaging (QPI) technology to provide a wide range of analytical applications including label-free cell imaging and quantitative electron phase microscopy. Here, they report on the Light Microscopy Science Technology Platform at the Francis Crick Institute’s selection of the Livecyte® label-free cell analysis system.

From Phasefocus 19 Jun 2017

Research reveals link between POMC neurons and release of insulin by the pancreas

The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of hypothalamus neurons, called POMC, that detect and integrate signals that inform on the energy state of the organism and activate the appropriate physiological responses.

8 Jun 2017

Light-sheet fluorescence microscopy manufacturer Luxendo acquired by Bruker

Bruker announces that it has acquired Luxendo, a privately held spin-off of the European Molecular Biology Laboratory (EMBL) that develops and manufactures proprietary light-sheet fluorescence microscopy instruments.

From Bruker Nano Surfaces and Metrology 9 May 2017

Microscopic probes simplify process of measuring electrical signals in small animals

Microscopic probes developed at Rice University have simplified the process of measuring electrical activity in individual cells of small living animals. The technique allows a single animal like a worm to be tested again and again and could revolutionize data-gathering for disease characterization and drug interactions.

17 Apr 2017

Using nanodiamonds to see smaller

Many of the most fundamental, life governing biological processes take place at size and time scales that remain invisible with current imaging technologies. Understanding how the molecules that underlie these processes move, interact and change could pave the way for new treatments, cures and the development of novel drug therapies.

From LuciGem 7 Apr 2017

Fluorescence Microscopy News and Research

Further Reading

Research reveals how Zika virus infection spurs fetal demise

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

Researchers release open-source dataset offering instructions to build smartphone microscope

Natural-shaped plastic nanoparticles could improve delivery of toxic drugs to tumors

Researchers identify link between circadian rhythm disturbance and brain dysfunction

NIH launches major effort to discover, catalog the brain's ‘parts list’

Measuring biological samples using SNAP

New way of tagging exosomes could have long term benefits in treatment of life-threatening conditions

New way of tagging exosomes could have long term benefits in treatment of life-threatening conditions

Optical Microscopy Resolution Revolution

Zirconia-doped ceria nanoparticles can act as effective antioxidants in sepsis treatment

Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

Francis Crick Institute selects Livecyte cell analysis system from Phasefocus

Research reveals link between POMC neurons and release of insulin by the pancreas

Light-sheet fluorescence microscopy manufacturer Luxendo acquired by Bruker

Microscopic probes simplify process of measuring electrical signals in small animals

Using nanodiamonds to see smaller

Researchers visualize development of blood vessels in zebrafish embryos

Micron Oxford advance their cellular imaging techniques using the super-resolution Nanoimager

UNIGE scientists identify complementary role played by two neurons in processing olfactory information

Fluorescence eBook

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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