Frontotemporal Dementia News and Research

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New Alzheimer's study to combine drugs targeting amyloid and tau proteins

A new study will combine an Alzheimer's medication that slows disease progression in some patients with two other drugs to see if their effects can be amplified.

12 Oct 2023

Cerebrospinal fluid leaks may be one of the mechanisms that link TBI with dementia

Cerebrospinal fluid (CSF) leaks may be one of the mechanisms that link traumatic brain injury (TBI) with dementia, according to a recently published hypothesis in Alzheimer's & Dementia: Translational Research & Clinical Interventions, a journal of the Alzheimer's Association.

21 Sep 2023

A review of the neurological imaging techniques in dementia diagnosis

Researchers reviewed existing data on the contribution of neuroimaging modalities such as magnetic resonance imaging.

28 Aug 2023

British neuroscientist wins Hartwig Piepenbrock-DZNE Prize for contributions to dementia research

This year's "Hartwig Piepenbrock-DZNE Prize", endowed with 60,000 euros, goes to the British neuroscientist Alison Goate, DPhil. The award recognizes her outstanding contributions to research into Alzheimer's disease and frontotemporal dementia.

13 Jul 2023

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs -; single-stranded RNAs involved in protein synthesis -; and proteins from the same stretch of DNA, plays an important role in molecular biology.

21 Jun 2023

Alarming rise: New cases of dementia surging in elderly population of Wales, UK

Dementia cases are increasing among the elderly population, with a rise in new diagnoses and a growing number of people living with the disease. This trend poses challenges for healthcare systems as the aging population with dementia continues to grow.

20 Jun 2023

Dementia can take a toll on financial health, as some families learn the hard way

Angela Reynolds knew her mother’s memory was slipping, but she didn’t realize how bad things had gotten until she started to untangle her mom’s finances: unpaid bills, unusual cash withdrawals, and the discovery that, oddly, the mortgage on the family home had been refinanced at a higher interest rate.

20 Jun 2023

Boiled coffee overload: Consuming six or more cups daily linked to higher dementia and Alzheimer's risk

Researchers examine the potential relationship between tea and coffee consumption during midlife and the risk of developing dementia in later life.

30 May 2023

Same genetic defects shared by some patients with motor neuron disease and frontotemporal dementia

New research has discovered that some patients with motor neuron disease (MND) and frontotemporal dementia (FTD) carry the same rare genetic defects that cause other neurodegenerative diseases.

9 May 2023

NIH researchers identify new genetic risk factors for two types of non-Alzheimer's dementia

Scientists at the National Institutes of Health have identified new genetic risk factors for two types of non-Alzheimer's dementia.

8 May 2023

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

Targeting part of an antiviral pathway triggered by the accumulation of a key pathogen shared in Alzheimer's disease and frontotemporal dementia may one day offer a new therapeutic approach to deterring or delaying cognitive decline, according to preclinical research led by Weill Cornell Medicine scientists.

24 Apr 2023

Study links astrocytic TDP-43 dysfunction to cognitive decline in dementia: Unlocking potential therapeutic strategies

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20 Apr 2023

Did COVID-19-associated lockdowns increase the rate of memory decline in patients with cognitive impairments?

Researchers investigated whether COVID-19-associated lockdown measures had an impact on the cognitive decline rate.

18 Apr 2023

SARS-CoV-2 infection significantly impacts cognitive function in patients with preexisting dementia

Infection with SARS-CoV-2 has a significant impact on cognitive function in patients with preexisting dementia, according to new research, published in the Journal of Alzheimer's Disease Reports.

4 Apr 2023

Designer DNA drug could be used to delay paralysis in ALS

In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell.

17 Mar 2023

Research investigates roles of neurotrophic factors on cognition in Alzheimer's patients carrying APOE ε4

Researchers investigate the role of neurotrophic factors on the cognitive performance of Alzheimer’s disease patients carrying the apolipoprotein E 4 gene.

1 Mar 2023

Common RNA modification plays a key role in TDP-43-related neurodegeneration in ALS

Nearly 100% of cases of amyotrophic lateral sclerosis-;the progressive, fatal neurodegenerative disease known as ALS or Lou Gherig's disease -; involve the buildup of a protein called TDP-43.

27 Feb 2023

UTHSC researchers secure $308,000 grant from Department of Defense for dementia study

Repeated traumatic brain injuries (TBI) in soldiers and military personnel can cause behavioral, neurological, and cognitive effects and lead to dementia.

19 Feb 2023

Cerebrospinal fluid leak may be a treatable cause of behavioral-variant frontotemporal dementia

A new Cedars-Sinai study suggests that some patients diagnosed with behavioral-variant frontotemporal dementia (bvFTD)-;an incurable condition that robs patients of the ability to control their behavior and cope with daily living-;may instead have a cerebrospinal fluid leak, which is often treatable.

24 Jan 2023

Researchers explore multi-syndrome prediction of dementia syndromes

A new study explored how support vector machines (SVMs) applied to magnetic resonance imaging (MRI) data can differentiate different dementia syndromes.

16 Jan 2023