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Inactivating a protective molecule may help chemotherapy for leukemia but harm bone marrow

Inactivating a protective molecule in leukemic cells to make them more vulnerable to chemotherapy might also make healthy blood-forming cells more sensitive to the toxic effects of those same drugs.

19 May 2004

Bio-optical CD could screen patients for thousands of disease markers while they wait

While-you-wait medical tests that screen patients for thousands of disease markers could be possible with compact-disk technology patented by Purdue University scientists.

19 May 2004

To sleep…

Proteomic analysis using mass spectrometry could be used in a diagnostic test for sleeping sickness that can more accurately spot the disease than current approaches.

18 May 2004

Matching method allows surgeons to successfully transplant kidneys that would otherwise be discarded

By carefully matching the estimated function of kidneys from deceased donors with the needs of potential recipients, surgeons can successfully transplant kidneys that would otherwise be discarded, according to a report from Wake Forest University Baptist Medical Center. The center was able to double its transplant volume within a year.

18 May 2004

High levels of troponin I (TNI) protein in the blood helps identify possible heart damage after cancer treatment

TNI is a protein present exclusively in heart cells. The TNI blood concentration is a well-established marker of heart muscle injury that’s widely used to diagnose and treat heart attacks and other acute coronary syndromes.

18 May 2004

Scientists move closer toward treatment for degenerative diseases

Scientists at McGill University's Faculty of Medicine have discovered a key step that will provide new targets for treatments of many degenerative diseases such as Alzheimer's, Cystic Fibrosis and Diabetes.

17 May 2004

Scientists have identified a compound that halts the activity of a deadly toxin called anthrax

University of Chicago scientists have identified a compound that halts the activity of a deadly toxin called anthrax lethal factor in laboratory tests. Nature Biotechnology will publish the findings online on May 16 and in the June issue of the journal's print edition.

17 May 2004

Researcher has learned how to maximize the cancer-fighting power of broccoli

University of Illinois researcher Elizabeth Jeffery has learned how to maximize the cancer-fighting power of broccoli. It involves heating broccoli just enough to eliminate a sulfur-grabbing protein, but not enough to stop the plant from releasing an important cancer-fighting compound called sulforaphane.

15 May 2004

Genetically engineered viruses may create new class of cancer therapies

A genetically engineered virus can selectively kill cancerous cells in the lung and colon while leaving healthy cells intact, according to new research published today in Cancer Research by William Wold and colleagues at Saint Louis University School of Medicine.

15 May 2004

Cancer-causing gene identified that may play a key role in the development of leukemia and other cancers

Using genetically engineered mice, researchers at the Johns Hopkins Children's Center have identified a gene that functions as a cancer-causing gene (or oncogene) and may play a key role in the development of leukemia and other cancers in children and adults.

15 May 2004

3 people with drug-resistant HIV become first to undergo a new form of gene therapy

The idea is to use a modified form of HIV to deliver an "antisense" gene to the immune cells that HIV infects. This is integrated into the cells' genome, and stays there until a cell is infected. Then it is switched on, and produces RNA complementary to the "sense" RNA encoding a viral protein. In theory, the RNAs should bind together, blocking viral replication.

14 May 2004

Australian researchers identify potential target to fight tumours

Dr Guishui Zhang and Associate Professor Levon Khachigian, from the Centre for Vascular Research, and Dr Nick Di Girolamo of the School of Medical Sciences were part of a team which suppressed a protein in the cells lining blood vessels.

14 May 2004

Breastfeeding decreases risk of heart disease later in life

A recent UK study of 216 teenagers, published in the Lancet, found that breastfeeding in infancy is likely to reduce the risk of atherosclerosis and cardiovascular disease in later life.

14 May 2004

Biochip technology to revolutionise the pharmaceutical industry

Advancements in biotechnology have culminated in its integration with semiconductor technologies such as micro-electromechanical systems, resulting in the evolution of biochips. Biochips provide pharma companies with sophisticated tools for speedy development of drugs and accurate diagnosis and understanding of biological mechanisms.

13 May 2004

Chromosome losses can signal an especially poor response to therapy

A new international study of children with a severe form of acute lymphoblastic leukemia(ALL) shows that certain chromosome losses can signal an especially poor response to therapy, but that other chromosome abnormalities have no effect on treatment survival.

13 May 2004

Nanobodies herald a new era in cancer therapy

Cancer, along with heart and vascular disease, is the major cause of death in the Western world. The first generation of anti-cancer drugs has already saved many lives, but because these medicines are non-specific they also often have severe side effects.

12 May 2004

Australian researchers are working on a vaccine to prevent rheumatic fever and rheumatic heart disease

The Queensland Institute of Medical Research (QIMR) Australia, is working on a vaccine to prevent rheumatic fever (RF) and rheumatic heart disease (RHD). Rheumatic fever and rheumatic heart disease are a secondary complication of a bacterial infection.

12 May 2004

Sharing functional magnetic resonance imaging (fMRI) data is quickly becoming a reality

The dream of saving and sharing functional magnetic resonance imaging (fMRI) data is quickly becoming a reality, according to Dartmouth researchers who run the fMRI Data Center, which archives and distributes the raw data from studies that track brain activity using fMRI.

11 May 2004

Critical link found between inflammation, heart disease and stroke

Until recently, the story on platelets was pretty simple: tiny blood cells, with limited sophistication because they had no nucleus, and their claim to fame was to be a first-responder to a wound site, to promote healthy clotting and prevent infection.

11 May 2004

Australian Federal Budget prepares for emerging health challenges

The 2004-2005 Federal Budget contains a package of measures to ensure that Australia is prepared for the emerging health challenges facing the nation.

11 May 2004

G Protein News and Research

Inactivating a protective molecule may help chemotherapy for leukemia but harm bone marrow

Bio-optical CD could screen patients for thousands of disease markers while they wait

To sleep…

Matching method allows surgeons to successfully transplant kidneys that would otherwise be discarded

High levels of troponin I (TNI) protein in the blood helps identify possible heart damage after cancer treatment

Scientists move closer toward treatment for degenerative diseases

Scientists have identified a compound that halts the activity of a deadly toxin called anthrax

Researcher has learned how to maximize the cancer-fighting power of broccoli

Genetically engineered viruses may create new class of cancer therapies

Cancer-causing gene identified that may play a key role in the development of leukemia and other cancers

3 people with drug-resistant HIV become first to undergo a new form of gene therapy

Australian researchers identify potential target to fight tumours

Breastfeeding decreases risk of heart disease later in life

Biochip technology to revolutionise the pharmaceutical industry

Chromosome losses can signal an especially poor response to therapy

Nanobodies herald a new era in cancer therapy

Australian researchers are working on a vaccine to prevent rheumatic fever and rheumatic heart disease

Sharing functional magnetic resonance imaging (fMRI) data is quickly becoming a reality

Critical link found between inflammation, heart disease and stroke

Australian Federal Budget prepares for emerging health challenges

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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