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Researchers use mixed realty viewer to visualize complex biological networks in 3D

They call it the "hairy ball." It's an unflattering name for two-dimensional representations of a complex biological network, a depiction of a system of linkages and connections so complex and dense that "it looks like a big mess," said Dmitry Korkin, PhD, associate professor of computer science at Worcester Polytechnic Institute and director of the university's bioinformatics and computational biology program.

13 Oct 2017

Scientists one step closer to unraveling mystery of how intrinsically disordered proteins work

Determining how proteins function on a molecular level is crucial to understanding the underlying basis for disease. Now scientists at the University of Notre Dame are one step closer to unraveling the mystery of how intrinsically disordered proteins work, according to new research published in Science

13 Oct 2017

Researchers find multiple new mutations linked to autism in children but not their parents

Most cases of autism appear to be associated with the appearance of new mutations that are not inherited from the child's parents, researchers from the University of Washington School of Medicine report.

12 Oct 2017

UC biologists find link between paternal diet and offspring’s health

Doctors long have stressed the importance of good nutrition for expectant mothers. Now biologists at the University of Cincinnati say the father's diet could play a similar role in the health of a baby.

12 Oct 2017

MIT researchers develop new technique to screen for genes that protect against diseases

Using a modified version of the CRISPR genome-editing system, MIT researchers have developed a new way to screen for genes that protect against specific diseases.

12 Oct 2017

Whole genome sequencing could help better understand genetic abnormalities underlying autism

An analysis of the complete genomes of 2,064 people reveals that multiple genetic variations could contribute to autism. The work suggests that scanning whole genomes may one day be useful for clinical diagnostics.Autism has genetic roots, but most cases can't be explained by current genetic tests.

12 Oct 2017

Juvenile idiopathic arthritis affects more than 300,000 children in the U.S.

When most people think of arthritis, they picture the knobby knuckles, inflamed joints or aching back of an older person. But more than 300,000 children in the U.S. suffer from chronic juvenile idiopathic arthritis (JIA), which has more to do with joint inflammation than wear and tear on cartilage and bone.

12 Oct 2017

Fundamental discovery may open potential for new types of cancer drugs

Many approved cancer therapies target a protein called epidermal growth factor receptor (EGFR) that regulates many crucial cellular processes and can speed the proliferation of tumor cells.

11 Oct 2017

Researchers find potential approach to prevent peripheral neuropathy

In discovering how certain chemotherapy drugs cause the nerve damage known as peripheral neuropathy, researchers at Dana-Farber Cancer Institute have found a potential approach to preventing this common and troublesome side effect of cancer treatment.

11 Oct 2017

Study: Protein known to play key role in psoriasis can be blocked without posing risk to patients

A protein known to play a significant role in the development of psoriasis can be prevented from functioning without posing a risk to patients, scientists at King's College London have found.

11 Oct 2017

CUMC researchers discover ‘cell of origin’ for esophageal cancer

Columbia University Medical Center researchers have identified cells in the upper digestive tract that can give rise to Barrett's esophagus, a precursor to esophageal cancer. The discovery of this "cell of origin" promises to accelerate the development of more precise screening tools and therapies for Barrett's esophagus and esophageal adenocarcinoma, the fastest growing form of cancer in the U.S.

11 Oct 2017

Calcium controls use of glucose by T cells to multiply and battle against infection, study finds

A calcium signal controls whether immune cells can use the nutrients needed to fuel their multiplication into a cellular army designed to fight invading viruses.

11 Oct 2017

Scientists identify protein as potential therapeutic target to fight against obesity

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have identified a protein that holds promise as a target for therapies to reduce obesity.

11 Oct 2017

Menopause causes metabolic changes in the brain that may increase Alzheimer's risk

Menopause causes metabolic changes in the brain that may increase the risk of Alzheimer's disease, a team from Weill Cornell Medicine and the University of Arizona Health Sciences has shown in new research.

10 Oct 2017

Scientists find new way to produce brain cells from single iPSC

Li Gan, PhD, wants to find treatments to help patients with Alzheimer's disease. Like most researchers, she's hit a few major roadblocks.

10 Oct 2017

Genetic discovery provides strong lead for future research on male contraception

When it comes to birth control, many males turn to two options: condoms or vasectomies. While the two choices are effective, both methods merely focus on blocking the transportation of sperm.

10 Oct 2017

FDA approved drug found to have anti-cancer activity against previously unknown targets

Developing new drugs to treat cancer can be a painstaking process taking over a decade from start to Food and Drug Administration approval. Scientists are trying to develop innovative strategies to identify and test new drugs quicker and more efficiently.

10 Oct 2017

BU professor receives $792,000 grant to study about aggressiveness of T-ALL

Hui Feng, MD, PhD, assistant professor of pharmacology and medicine at Boston University School of Medicine, is the recipient of a four-year, $792,000 grant from the American Cancer Society to study why T-cell acute lymphoblastic leukemia (T-ALL) is so aggressive and resistant to treatment.

10 Oct 2017

Experts indicate new way via which tumor cells can respond to chemotherapy

An international group of researchers, with the participation of the members of the University of Seville and the Andalusian Centre of Molecular Biology and Regenerative Medicine has just published a study in the prestigious review Science, in which they describe a new methodology for making tumor cells behave when submitted to chemotherapy, which, in the hope of new treatments, continues to be a fundamental tool in the fight against cancer.

10 Oct 2017

Newly discovered compound causes cancer cell death, whilst sparing healthy cells

Researchers have discovered a compound that can trigger cancer cells to self-destruct, without causing any damage to healthy cells.

10 Oct 2017

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G Protein News and Research

Researchers use mixed realty viewer to visualize complex biological networks in 3D

Scientists one step closer to unraveling mystery of how intrinsically disordered proteins work

Researchers find multiple new mutations linked to autism in children but not their parents

UC biologists find link between paternal diet and offspring’s health

MIT researchers develop new technique to screen for genes that protect against diseases

Whole genome sequencing could help better understand genetic abnormalities underlying autism

Juvenile idiopathic arthritis affects more than 300,000 children in the U.S.

Fundamental discovery may open potential for new types of cancer drugs

Researchers find potential approach to prevent peripheral neuropathy

Study: Protein known to play key role in psoriasis can be blocked without posing risk to patients

CUMC researchers discover ‘cell of origin’ for esophageal cancer

Calcium controls use of glucose by T cells to multiply and battle against infection, study finds

Scientists identify protein as potential therapeutic target to fight against obesity

Menopause causes metabolic changes in the brain that may increase Alzheimer's risk

Scientists find new way to produce brain cells from single iPSC

Genetic discovery provides strong lead for future research on male contraception

FDA approved drug found to have anti-cancer activity against previously unknown targets

BU professor receives $792,000 grant to study about aggressiveness of T-ALL

Experts indicate new way via which tumor cells can respond to chemotherapy

Newly discovered compound causes cancer cell death, whilst sparing healthy cells

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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