Gadolinium News and Research

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Researchers develop metal-free contrast agent that could be safer for high-risk patients

To enhance the visibility of organs as they are scanned with magnetic resonance imaging (MRI), patients are usually injected with a compound known as a contrast agent before going into the scanner. The most commonly used MRI contrast agents are based on the metal gadolinium; however, these metal compounds can be harmful for young children or people with kidney problems.

13 Jul 2017

UMMS scientists design human protein-based tumor-targeting MRI contrast agent

A team led by Gang Han, PhD, has designed a human protein-based, tumor-targeting Magnetic Resonance Imaging contrast that can be easily cleared by the body.

10 Jul 2017

Study: Gadolinium may accumulate in brain tissues of patients without intracranial abnormalities

Minute traces of gadolinium, the contrast agent used to enhance MR images, are often retained in the brain tissue of patients years after undergoing MRI. Some studies have suggested this deposition was limited to patients with underlying brain pathology, such as a tumor or infection.

28 Jun 2017

Researchers develop nano-contrast agents for MRI and optical imaging of cancer cells

Researchers from PSG College of Technology, India have developed nano-contrast agents for magnetic resonance imaging (MRI) as well as optical imaging of cancer cells. This report will appear in the forthcoming issue of the journal NANO.

20 Jun 2017

Newly developed ultrafast cardiac imaging test changes clinical management in one-third of patients

Researchers in the UK and Peru have developed a faster and cheaper cardiac imaging test that can be used in developing countries, according to the results of the INCA-Peru study presented today at EuroCMR 2017.

26 May 2017

Molecular drug imaging likely to benefit children with brain tumors

Brain cancers are difficult to treat, and it can be hard to predict whether a therapy will be effective. When the patient is a child, it's even more important to predict the potential effectiveness of a drug before beginning treatment.

3 May 2017

Monoenergetic X-rays from miniature particle accelerator can reduce use of contrast agents

The most prevalent method for obtaining images of clogged coronary vessels is coronary angiography. For some patients, however, the contrast agents used in this process can cause health problems.

1 Mar 2017

Researchers develop new iron oxide nanoparticles as contrast agent for MRI

A new, specially coated iron oxide nanoparticle developed by a team at MIT and elsewhere could provide an alternative to conventional gadolinium-based contrast agents used for magnetic resonance imaging procedures.

14 Feb 2017

IBS scientists develop Nano MRI Lamp for smarter diagnosis of diseases

A research team led by CHEON Jinwoo at the Center for Nanomedicine, within the Institute for Basic Science, developed the Nano MRI Lamp: A new technology platform that tunes the magnetic resonance imaging signals "ON" only in the presence of the targeted disease.

6 Feb 2017

Rayence to unveil new line of wireless flat panel detectors at RSNA 2016

Today, Rayence Inc. announced the latest entries to its growing line of wireless flat panel detectors will be shown at RSNA 2016 in Chicago, Illinois.

21 Nov 2016

Non-contrast MRA can be viable diagnostic alternative for patients with chronic kidney disease

Patients with diabetes or renal failure are at high risk for deadly and debilitating vascular diseases, however, the most common imaging tool to evaluate the blood vessels uses a contrast agent that can further damage the kidneys.

30 Sep 2016

Revolutionary new scanning technique creates 3D images of bones with unparalleled resolution

Chemists from Trinity College Dublin in collaboration with RCSI have devised a revolutionary new scanning technique that produces extremely high-res 3D images of bones -- without exposing patients to X-ray radiation.

13 Sep 2016

Study evaluates long-term safety of infants after maternal MRI exposure

In an analysis that included more than 1.4 million births, exposure to magnetic resonance imaging (MRI) during the first trimester of pregnancy compared with nonexposure was not associated with increased risk of harm to the fetus or in early childhood, although gadolinium MRI at any time during pregnancy was associated with an increased risk of a broad set of rheumatological, inflammatory, or skin conditions and, possibly, for stillbirth or neonatal death, according to a study appearing in the September 6 issue of JAMA.

6 Sep 2016

Study shows leptomeningeal metastases more prevalent in NSCLC patients with EGFR mutations

Leptomeningeal metastases (LM), a devastating complication and predictor of poor survival in lung cancer patients, was found to be more prevalent in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations.

16 Aug 2016

Study finds no increased risk for parkinsonism linked to use of gadolinium in MRIs

A new study from Lawson Health Research Institute and the Institute for Clinical Evaluative Sciences has cast doubt on the clinical significance of brain deposits of gadolinium.

19 Jul 2016

Study finds no substantial link between gadolinium exposure and parkinsonism

In a study appearing in the July 5 issue of JAMA, Blayne Welk, M.D., M.Sc., of Western University, London, Canada, and colleagues conducted a study to assess the association between gadolinium exposure and parkinsonism, a degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination.

6 Jul 2016

Switch to rituximab shows anti-inflammatory effect in relapsing-remitting MS

Rituximab may be an attractive treatment option for patients with relapsing-remitting multiple sclerosis, suggest phase II study findings showing its efficacy in controlling inflammatory activity.

22 Jun 2016

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that tiny particles made of a biodegradable polymer (BNPs -- biodegradable polymer nanoparticles) have the potential to enable early detection and efficient long-term treatment of rheumatoid arthritis (RA), with minimal side effects.

10 Jun 2016

Real risk of rebound syndrome following fingolimod cessation for MS

Rebound syndrome following cessation of fingolimod for multiple sclerosis occurs at a clinically relevant rate, shows research, prompting the need for further study on how best to sequence and discontinue such drugs.

4 May 2016

New chemical probe could tag cells for detection by MRI

The need to non-invasively "see" and track cells in living persons is indisputable - a boon to both research and development of future therapies. Emerging treatments using stem cells and immune cells are poised to most benefit from cell tracking, which would visualize their behavior in the body after delivery. Clinicians require such data to speed these cell treatments to patients.

15 Mar 2016