Ganglion News and Research

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In anatomy, a ganglion (plural ''ganglia'') is a biological tissue mass, most commonly a mass of nerve cell bodies. Cells found in a ganglion are called ganglion cells, though this term is also sometimes used to refer specifically to retinal ganglion cells.

AI-powered eye scans could revolutionize early detection of Parkinson's

Markers that indicate the presence of Parkinson's disease in patients on average seven years before clinical presentation have been identified by a UCL and Moorfields Eye Hospital research team.

21 Aug 2023

Review examines visual disturbances among Parkinson’s disease patients

In a recent review published in Brain Sciences, researchers reviewed existing data on visual impairments among Parkinson’s disease (PD) patients.

9 Aug 2023

Can light exposure behaviors predict chronotype, sleep quality, mood, memory, and concentration?

Researchers aimed to understand the influences of Light Exposure Behavior Assessment (LEBA) categories on chronotype, mood, sleep quality, memory, and concentration.

3 Aug 2023

New insights into how axons grow could lead to effective therapies for blindness, paralysis

Injuries to the nerves can blind or paralyze because adult nerve cells don't regenerate their connections. Now, a team of UConn School of Medicine researchers report in Development that at least a small population of nerve cells exist in everyone that could be coaxed to regrow, potentially restoring sight and movement.

31 May 2023

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Melatonin, a hormone derived from the pineal gland, has diverse effects on cellular processes. This review explores its potential role as an epigenetic regulator, particularly in modulating DNA methylation, and suggests its use in combination therapy as a novel anticancer strategy.

30 May 2023

Stimulating a bile acid receptor can help protect the vision of premature newborns

It sounds like bile acid in the eye would hurt, but scientists think stimulating one of its receptors can actually help protect the vision of premature newborns.

30 May 2023

Research could help develop better treatments for swallowing disorders

Sensory cells in the vagus nerve can detect and locate food in the esophagus. Their signals help transport the food onward to the stomach. Signal failure leads to swallowing disorders, say a team led by Carmen Birchmeier at the Max Delbrück Center.

26 May 2023

High-resolution atlas illustrates the development of human retina

What cell types are found in which human tissue, and where? Which genes are active in the individual cells, and which proteins are found there?

8 May 2023

Neuropathic pain study uncovers pathophysiological mechanism and promising therapeutic target

Neuropathic pain -; abnormal hypersensitivity to stimuli -; is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from neuropathic pain, including a quarter of people with diabetes and a third of people with HIV.

5 May 2023

Neutrophils found to play a key role in fibromyalgia pain

Targeting neutrophil activity and interactions with sensory neurons may be a potential approach for treating fibromyalgia pain.

25 Apr 2023

Dormant cone photoreceptors in the degenerating retina may retain visual function, research suggests

New UCLA research in mice suggests that "dormant" cone photoreceptors in the degenerating retina are not dormant at all, but continue to function, producing responses to light and driving retinal activity for vision.

27 Mar 2023

Newly identified therapeutic target could lead to more effective treatment of glaucoma

Indiana University School of Medicine researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.

10 Mar 2023

The role of caffeine in preventing diabetic retinopathy

Moderate and high caffeine intake offered protection against the development of diabetic retinopathy.

5 Mar 2023

Analysis provides new insights into complex effects of Alzheimer’s disease on the retina

Cedars-Sinai investigators have produced the most extensive analysis to date of changes in the retina-;a layer of tissue at the back of the eye where visual information originates-;and how those retinal changes correspond to brain and cognitive changes in Alzheimer's disease patients.

3 Mar 2023

Cochlear avatars provide a platform for deciphering the mechanisms of sensorineural hearing loss

Disabling hearing loss affects one in every ten people and up to 25% of people over 60, according to the World Health Organization, and can have both genetic and environmental causes such as infections and noise exposure.

1 Feb 2023

Researchers discover mechanism underlying the development and intensification of cancer treatment-related pain

A combination of chemotherapy and drugs that stimulate the immune system to combat cancer is increasingly used to control progression of the disease in patients.

30 Jan 2023

Study shows cutaneous touch neuronal cells to be critical for sexual receptiveness

Researchers studied the social relevance of G protein-coupled receptor (GPCR) Mrgprb4-lineage touch neurons in sexual touch and receptivity.

25 Jan 2023

Artificial light affects glucose metabolism

Researchers assess the hypothalamus as a possible mediator of the effect of light on metabolism.

24 Jan 2023

Therapeutic small molecule can restore visual functions after optic nerve injury

Traumatic injury to the brain, spinal cord and optic nerve in the central nervous system (CNS) are the leading cause of disability and the second leading cause of death worldwide.

20 Jan 2023

What are the major findings of long COVID research?

Researchers explored existing literature on long coronavirus disease (COVID). They highlighted key immunological findings, similarities with other diseases, symptoms, and associated pathophysiological mechanisms, and diagnostic and therapeutic options, including COVID-19 vaccinations.

17 Jan 2023