Gangrene News and Research

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Gangrene is a type of tissue death which occurs due to loss of blood supply. This may affect any part of the body but usually affects the peripheral extremities like feet, toes, fingers, hands, penis etc.

Keeping blood sugar levels under control can help protect hearts from diabetes-related damage

Day in and day out, for years on end, millions of people with diabetes prick their fingers to test their blood sugar level. And many may wonder if all the careful eating, exercise and medication it takes to keep those levels under control is really worth it.

4 Jun 2015

Diabetic neuropathy highly prevalent among diabetic patients in Romania

A survey of 25,000 Romanians with diabetes has revealed that diabetic neuropathy (DN), a complication of diabetes, is highly prevalent in these patients, even in the absence of a diagnostic, and has an important impact on patients' quality of life.

6 May 2015

Study explains why generic insulin remains out of reach for diabetes patients

A generic version of insulin, the lifesaving diabetes drug used by 6 million people in the United States, has never been available in this country because drug companies have made incremental improvements that kept insulin under patent from 1923 to 2014.

23 Mar 2015

Scripps Green Hospital treats peripheral artery disease patient using new drug-coated balloon

A doctor at Scripps Green Hospital this week became the first in California to use a new drug-coated balloon to treat peripheral artery disease in a patient since regulatory approval of the IN.PACT Admiral device in January by the Food and Drug Administration.

5 Feb 2015

Rose Medical Center becomes first hospital in Colorado to perform new procedure for PAD patients

Rose Medical Center is the first hospital in Colorado to perform a new and innovative procedure for patients with peripheral arterial disease (PAD). Utilizing the Lutonix 035 Drug Coated Balloon PTA Catheter, surgeons are able to perform a balloon angioplasty in patients with PAD using a special drug-coated balloon (DCB) that delivers a small amount of medication to the inside walls of the diseased portion of the artery.

12 Nov 2014

Research opens door to potential new treatments for peripheral artery disease

Researchers have developed a technique to jump-start the body's systems for creating blood vessels, opening the door for potential new treatments for diseases whose impacts include amputation and blindness.

14 Oct 2014

‘Reassuring’ findings on microvascular risk in diabetic statin users

Statin treatment prior to diabetes onset does not appear to increase the risk of microvascular disease and may even be protective against some forms, findings from a registry study suggest.

17 Sep 2014

New research shows statins could reduce common diabetes complications

The development of common diabetes complications that can lead to blindness and amputations could be reduced by taking statins, indicates new research published in The Lancet Diabetes & Endocrinology.

11 Sep 2014

Diabetics who live in low-income neighborhoods are up to 10 times more likely to lose toe, foot, leg

It's no secret that poverty is bad for your health. Now a new UCLA study demonstrates that California diabetics who live in low-income neighborhoods are up to 10 times more likely to lose a toe, foot or leg than patients residing in more affluent areas of the state.

5 Aug 2014

Freiburg researchers discover molecule that smuggles toxins from intestinal pathogens into human cells

Prof. Dr. Dr. Klaus Aktories and Dr. Panagiotis Papatheodorou from the Institute of Experimental and Clinical Pharmacology and Toxicology of the University of Freiburg have discovered the receptor responsible for smuggling the toxin of the bacterium Clostridium perfringens into the cell.

17 Apr 2014

Research explains how cells behave when placed in low oxygen environment

Research at the University of Liverpool has explained how cells behave when placed in a low oxygen environment, a development that could have implications for cancer patients and other serious illnesses.

24 Feb 2014

Researchers awarded $25 million NIH grant to study critical limb ischemia treatment

A team of researchers from Brigham and Women's Hospital, Boston Medical Center and Massachusetts General Hospital has been awarded $25 million by the National Institutes of Health to conduct a four-year, randomized clinical trial-the BEST-CLI Trial (Best Endovascular versus Best Surgical Therapy in Patients with Critical Limb Ischemia). The trial will compare traditional bypass surgery with the less invasive alternative of endovascular treatment for patients with critical limb ischemia.

11 Dec 2013

‘Flesh-eating’ disease treatments: an interview with Dr. John Crew, Seton Medical Center

Untreated, the mortality probably exceeds 70%. Flesh eating is a description of Toxic Inflammatory Cellulitis which usually starts by bacterial subcutaneous infection followed by freezing in phase II healing which is inflammatory.

9 Dec 2013

Study: Compared to open bypass, stenting keeps circulation flowing longer in some patients

New Johns Hopkins research suggests that people who undergo minimally invasive placement of stents to open clogged leg arteries are significantly less likely than those who have conventional bypass surgery to need a second treatment for the condition within two years.

8 Aug 2013

State highlights: Court hears arguments on Fla. 'gun-gag' law; Univ. of Minn. seeks to scale back coverage; fewer Utah docs see Medicaid patients

The top attorney for the state of Florida asked a federal appeals court today to reinstate a Florida law that regulates what physicians can ask patients about gun ownership, asserting that the law does not actually stifle such questions. Yes, it does, countered a lawyer representing several Florida medical societies and individual physicians who challenged the law as an infringement on their First Amendment right to free speech (Lowes, 7/18).

20 Jul 2013

Inovio's electroporation technology enhances ability of DNA therapy to stimulate blood vessel growth

Inovio Pharmaceuticals, Inc. announced today that the use of its proprietary electroporation technology significantly enhanced the ability of a DNA therapy to stimulate blood vessel growth, which may be beneficial for the treatment of critical limb ischemia and other forms of peripheral arterial disease.

18 Jul 2013

Mayo Clinic research shows that revascularization has reduced need for amputations by 40%

Peripheral arterial disease is a common circulation problem in which reduced blood flow can lead to complications that jeopardize the limbs, possibly even requiring amputation. Procedures known as revascularization have reduced the need for amputations 40 percent over two decades, Mayo Clinic research shows.

1 Jun 2013

Cook receives FDA approval for Zilver PTX Drug-Eluting Peripheral Stent to treat PAD

The U.S. Food and Drug Administration approved the Zilver PTX Drug-Eluting Peripheral Stent (Zilver PTX Stent), the first drug-eluting stent indicated to re-open a particular artery in the thigh (femoropopliteal artery) when narrowed or blocked as a result of peripheral artery disease (PAD).

15 Nov 2012

U.S. Marshals seize dietary supplements and unapproved drugs from Confidence

At the request of the U.S. Food and Drug Administration, U.S. Marshals recently seized dietary supplements and unapproved drugs from Confidence, Inc., of Port Washington, N.Y.

24 Oct 2012

FOS prebiotic could replace intravenous feeding in pediatric patients with intestinal failure

Adding the right prebiotic to the diets of pediatric patients with intestinal failure could replace intravenous feeding, says a new University of Illinois study.

16 Oct 2012