Gangrene News and Research

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Gangrene is a type of tissue death which occurs due to loss of blood supply. This may affect any part of the body but usually affects the peripheral extremities like feet, toes, fingers, hands, penis etc.

Depressed patients at risk of developing peripheral artery disease

Depression was linked with an increased risk of peripheral artery disease (PAD) in a study of more than one thousand men and women with heart disease conducted by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

10 Aug 2012

Scientists identify biological mechanism that may be responsible for icy extremities

Cold feet-those chilly appendages that plague many people in the winter and an unlucky few all year round-can be the bane of existence for singles and couples alike. In a new study, scientists led by Selvi C. Jeyaraj of the Research Institute at Nationwide Children's Hospital have identified a biological mechanism that may be responsible for icy extremities: an interaction between a series of molecules and receptors on smooth muscle cells that line the skin's tiny blood vessels.

1 Aug 2012

Blood flow in blocked arteries to extremities improved by new angioplasty procedure

Patients with blocked arteries to their extremities, known as peripheral artery disease (PAD) or critical limb ischemia (CLI), may now find relief from lower leg pain and wounds caused by impaired leg artery circulation with the previously unproven therapy, percutaneous transluminal angioplasty (PTA).

24 Jul 2012

Erasing neuronal memories may help control persistent pain

For some, the pain is so great that they can't even bear to have clothes touch their skin. For others, it means that every step is a deliberate and agonizing choice. Whether the pain is caused by arthritic joints, an injury to a nerve or a disease like fibromyalgia, research now suggests there are new solutions for those who suffer from chronic pain.

13 Feb 2012

Earthquakes devastating in more ways than one: Review

According to a new study published Thursday in the Lancet earthquakes can be devastating during and after they have come and gone.

6 Nov 2011

Exenatide's rapid anti-inflammatory effect may inhibit atherosclerosis

Exenatide, a drug commonly prescribed to help patients with type 2 diabetes improve blood sugar control, also has a powerful and rapid anti-inflammatory effect, a University at Buffalo study has shown.

3 Nov 2011

Exercise, intervention may help individuals with peripheral arterial disease

Peripheral arterial disease, or PAD, is a common condition affecting 12-20 percent of Americans age 65 and older that may be a signal of future heart attack and stroke-and many with the disease may be unaware they have it, says the Society of Interventional Radiology.

8 Sep 2011

Dorsogluteal buttock site still most popular despite known potential for sciatic nerve injury

Seven out of ten hospital nurses who took part in a Canadian study used the dorsogluteal (DG) buttock site to administer intramuscular injections - despite the potential risks of sciatic nerve injury - with only 14% using the ventrogluteal (VG) hip site recommended by the nursing literature.

10 May 2011

Young new nurses more likely to follow latest VG site advice to administer intramuscular injections

Seven out of ten hospital nurses who took part in a Canadian study used the dorsogluteal buttock site to administer intramuscular injections - despite the potential risks of sciatic nerve injury - with only 14% using the ventrogluteal hip site recommended by the nursing literature.

9 May 2011

FDA approves Harvest's BMAC System IDE trial to treat non-reconstructable Critical Limb Ischemia

Harvest Technologies Corp. announced today that the FDA has approved the company sponsored 210-patient IDE clinical trial to be conducted at twenty-five sites in the U.S. using the company's proprietary Bone Marrow Aspiration Concentrate (BMAC) System to treat patients with non-reconstructable Critical Limb Ischemia (CLI).

23 Mar 2011

Treatment with sildenafil significantly reduces RP in patients with scleroderma

Researchers in Europe reported that treatment with modified-release sildenafil significantly reduced the frequency of attacks of Raynaud's phenomenon in patients with limited cutaneous systemic sclerosis, also known as scleroderma.

8 Mar 2011

TGMC installs third Toshiba Infinix DP-i system with Next Generation Advanced Image Processing

As a nationally recognized healthcare organization, home to one of the most advanced vascular interventional practices in the country, Terrebonne General Medical Center (TGMC) handles approximately 3,300 cath lab patients annually. Patients from all over the country come to TGMC for interventional treatment for conditions associated with cardiovascular disease (CVD) and peripheral vascular disease (PVD), including limb ischemia.

10 Feb 2011

People can encounter common hazards like frostbite, frostnip during winter

Winter can be especially hazardous to human health with frostbite and frostnip being among the more common hazards people are likely to encounter. Frostbite and frostnip occur when the human body is exposed to extremely low temperatures for a period of time without the proper clothing for the conditions. Extreme cold causes the blood vessels of the body to begin to narrow and constrict, reducing blood flow to the extremities, such as ears, the nose, hands and feet.

5 Feb 2011

CVBT seeks FDA 'fast track' designation for CVBT-141B to treat ischemic diabetic wounds

CardioVascular BioTherapeutics, Inc. today announced it has submitted an application to the U.S. FDA to obtain "fast track" designation for CVBT-141B, its biological therapy to treat ischemic diabetic wounds based on the active ingredient fibroblast growth factor-1 (FGF-1).

4 Feb 2011

Stem cell therapy helps patient with diabetes gangrene recover from foot ulcer: ICMS conference

During ICMS Annual International Congress on Regenerative and Cell Based Medicine Conference held on November 12, 2010 in Las Vegas, Nevada, it was announced that a patient with complications of diabetes gangrene recovered from foot ulcer through stem cell therapy.

27 Dec 2010

Aastrom announces interim analysis of Phase 2b RESTORE-CLI clinical trial for treatment failure

Aastrom Biosciences, Inc., a leading developer of expanded autologous cellular therapies for the treatment of severe cardiovascular diseases, today announced that an interim analysis of all 86 patients enrolled in the company's Phase 2b RESTORE-CLI clinical trial shows that the study achieved both its primary safety endpoint and primary efficacy endpoint of time to first occurrence of treatment failure.

19 Nov 2010

New balloon angioplasty device could trigger a 'paradign shift' in PAD treatment

A balloon angioplasty device that sucks up dangerous plaque debris could trigger a "paradign shift" in how physicians treat peripheral artery disease, researchers write in the current issue of Endovascular Today.

6 Oct 2010

Best P.A.D. Research Awards honor investigators for research on peripheral arterial disease

The Peripheral Arterial Disease (P.A.D.) Coalition presented the Coalition's second annual Best P.A.D. Research Awards to the top three research papers on P.A.D. published in 2009 at the organization's Seventh Annual Meeting in Alexandria, VA last week. The Best P.A.D. Research Awards honor the work of investigators and acknowledge the creation of new clinical research relevant to the understanding and/or treatment of peripheral arterial disease.

30 Sep 2010

FDA guides Apricus Bio on RayVa's approvability for Raynaud's syndrome secondary to scleroderma

Apricus Biosciences, backed by a revenue-generating CRO business and seeking to leverage its multi-route NexACT® drug delivery technology and internal pipeline through out-licensing partnerships, announced today that the U.S. Food and Drug Administration (FDA) has provided guidance on the clinical requirements for assessing the approvability of RayVa for the treatment of Raynaud's syndrome secondary to scleroderma.

22 Sep 2010

Podiatrist reduces leg amputation risk in diabetics: Study

People with diabetic foot problems can lower their risk of leg amputation by relying on coordinated care that includes a podiatrist, according to a recent study. For instance, those with diabetes-related foot ulcers can reduce their risk of amputation by 31 percent.

19 Aug 2010