Gastroesophageal Reflux Disease News and Research

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Gastroesophageal reflux disease (GERD) is a more serious form of gastroesophageal reflux (GER), which is common. GER occurs when the lower esophageal sphincter (LES) opens spontaneously, for varying periods of time, or does not close properly and stomach contents rise up into the esophagus. GER is also called acid reflux or acid regurgitation, because digestive juices—called acids—rise up with the food. The esophagus is the tube that carries food from the mouth to the stomach. The LES is a ring of muscle at the bottom of the esophagus that acts like a valve between the esophagus and stomach.

Anti-reflux surgery - research may lead to changes in treatment recommendations

Researchers at Wake Forest University Baptist Medical Center have found that the reflux and swallowing problems that are common symptoms in patients with Rett syndrome and other neurological impairments, may be caused by a different mechanism than they are in healthy individuals. The finding leaves researchers to wonder if these patients truly benefit from anti-reflux surgery commonly performed in these children.

4 Aug 2008

Gastroesophageal reflux disease and asthma

Researchers at Duke University Medical Center appear to have solved at least a piece of a puzzle that has mystified physicians for years: why so many patients with asthma also suffer from GERD, or gastroesophageal reflux disease.

21 Jul 2008

Patent for Aciphex ruled valid and enforceable

PriCara, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc., announced today that the U.S. Federal Circuit Court of Appeals affirmed the judgments of the United States District Court for the Southern District of New York that the patent for Aciphex (rabeprazole sodium 20 mg tablets) is valid and enforceable.

21 Jul 2008

HALO Ablation System shows great promise for precancerous esophagus disease

BARRX Medical, Inc. has announced that 98.4 percent of patients having a precancerous condition of their esophagus called Barrett's esophagus were free of the disease 2.5 years after non-surgical, endoscopic treatment with the HALO ablation system.

21 Jul 2008

Stem cells help keep the brain healthy and active

For some years, scientists have been speculating over why stem cells exist in the brain, as brain regeneration is limited. A German team of neuroscientists believe these stem cells help keep the brain healthy and active.

13 Jul 2008

Nuclear medicine imaging test could aid children suffering from reflux disease

A nuclear medicine imaging test was used to confirm that children with respiratory problems may be more likely to develop gastroesophageal reflux disease, according to researchers at Society of Nuclear Medicine's 55th Annual Meeting.

16 Jun 2008

Arsenic and new rice

Amid recent reports of dangerous levels of arsenic being found in some baby rice products, scientists have found a protein in plants that could help to reduce the toxic content of crops grown in environments with high levels of this poisonous metal.

10 Jun 2008

Global drug research programme comes to Diamond in Oxfordshire

Diamond has announced that USA-based global biotechnology company Vertex Pharmaceuticals Incorporated is the first industrial user at the UK's world class new research facility, Diamond Light Source

27 May 2008

FDA grants priority review for ACIPHEX (rabeprazole sodium) sNDA for treatment of GERD in adolescents

Eisai Corporation of North America, a wholly-owned subsidiary of Tokyo-based Eisai Co., Ltd., has announced that the Food and Drug Administration (FDA) has accepted an ACIPHEX supplemental New Drug Application (sNDA) for the short-term (up to eight weeks) treatment of gastroesophageal reflux disease (GERD) in patients ages 12-16.

3 Mar 2008

FDA approves Nexium for gastroesophageal reflux disease in children

The U.S. Food and Drug Administration approved Nexium (esomeprazole magnesium) for short-term use in children ages 1-11 years for the treatment of gastroesophageal reflux disease (GERD).

28 Feb 2008

Ranbaxy receives tentative approval for Esomeprazole Magnesium delayed-release capsules

Ranbaxy Laboratories Limited has announced that it has received tentative approval from the U.S. Food and Drug Administration for Esomeprazole Magnesium Delayed-Release Capsules, 20 mg (base) and 40 mg (base).

8 Feb 2008

Hospitalizations for gastroespohageal reflux disease on the rise

Hospitalizations for treating disorders caused by gastroespohageal reflux disease (GERD ) increased by 103 percent between 1998 and 2005, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

7 Jan 2008

Popular heartburn drug given the all clear

Concerns that a drug used to treat stomach conditions such as heartburn could cause heart problems have been laid to rest by a comprehensive review.

11 Dec 2007

FDA concludes no increased risk of cardiac events for patients treated with omeprazole and Nexium

The US Food and Drug Administration (FDA) has issued its final assessment of two small, open, long-term, clinical studies in patients with gastro-esophageal reflux disease (GERD), comparing anti-reflux surgery with either omeprazole (SOPRAN study) or NEXIUM (LOTUS study) treatment.

10 Dec 2007

Heartburn during pregnancy

Heartburn symptoms are one of the most commonly reported complaints among pregnant women.

10 Dec 2007

Incisionless surgery for acid reflux disease

Surgeons at the Ohio State University Medical Center have performed the first incisionless operations in the United States using a device recently approved by the Food and Drug Administration to stop gastroesophageal reflux disease.

24 Oct 2007

Nighttime acid reflux and sleep

According to results of a survey presented at the 72nd Annual Scientific Meeting of the American College of Gastroenterology, nighttime acid reflux, along with some of the less typical manifestations or symptoms of gastroesophageal reflux disease (GERD), is associated with significant sleep impairment.

16 Oct 2007

Night-time acid reflux can impact sleep

16 Oct 2007

Gastrointestinal disorders and work-related absenteeism

Those who suffer from common functional gastrointestinal disorders face work productivity losses and impairments in daily activity that amount to the loss of at least one day of work in a 40-hour workweek, according to a new study presented at the Annual Scientific Meeting of the American College of Gastroenterology.

16 Oct 2007

GERD can masquerade as persistent cough or even severe chest pain

Many people may not realize that symptoms such as chronic cough or chest pain can be caused by acid reflux into the esophagus, because they do not experience classic heartburn symptoms or acid regurgitation.

16 Oct 2007