Gastrointestinal Cancer News and Research

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Gastrointestinal cancer refers to malignant conditions of the gastrointestinal tract, including the esophagus, stomach, liver, biliary system, pancreas, bowels, and anus.

Salk scientists uncover surprising role of tuft cells in pancreatitis

Persistent inflammation of the pancreas (chronic pancreatitis) is a known risk factor for developing pancreatic cancer, the third-deadliest cancer in the United States.

18 Apr 2020

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Oncotarget Volume 11, Issue 10 reported that dysregulation of noncoding micro RNA molecules has been associated with immune cell activation in the context of Helicobacter pylori-induced gastric inflammation as well as carcinogenesis, but also with downregulation of mismatch repair genes, and may interfere with immune checkpoint proteins that lead to the overexpression of antigens on gastric tumor cells.

13 Mar 2020

Study provides new details about therapy-associated polyposis in childhood cancer survivors

In a paper published online today, Dana-Farber Cancer Institute researchers provide new details about a recently discovered condition in which childhood cancer survivors develop numerous colorectal growths called polyps despite not having a hereditary susceptibility to the condition.

12 Feb 2020

Study reveals new mechanism involved in the pathogenesis of IBD

Inflammatory bowel disease is a category of refractory inflammatory disease, of which ulcerative colitis and Crohn's disease are the main types.

21 Jan 2020

Cystic fibrosis carriers have higher risk for all CF-related conditions

Conventional wisdom says that having just one mutated copy of the cystic fibrosis gene has no effects on a person's health--the disease occurs when both copies of the gene are mutated. But a new study from the University of Iowa suggests that may not be the case.

8 Jan 2020

Proton therapy reduces the relative risk of side effects for cancer patients

Proton therapy leads to significantly lower risk of side effects severe enough to lead to unplanned hospitalizations for cancer patients when compared with traditional radiation, while cure rates between the two groups are almost identical.

26 Dec 2019

Artificial Intelligence (AI) in Cancer Care

Artificial intelligence (AI) is being tested in clinics around the world, but is it a realistic ambition to apply sophisticated algorithms to cancer care?

From IBM Watson 12 Dec 2019

Diet high in fiber and yogurt linked with reduced risk for lung cancer

A diet high in fiber and yogurt is associated with a reduced risk for lung cancer, according to a study by Vanderbilt University Medical Center researchers published in JAMA Oncology.

25 Oct 2019

Study represents a major step in seeking alternative cancer treatments for non-responders

Research led by VHIO's Alena Gros signposts a new, less invasive approach to identify killer T lymphocytes in patients with gastrointestinal tumors with low mutational burden who are refractory to approved immune-based treatments.

16 Oct 2019

New trial shows improved survival for patients with advanced colorectal BRAF-mutant cancer

A clinical trial has shown that using a combination of three drugs that target a BRAF gene mutation in patients with mCRC effectively boosts overall survival.

30 Sep 2019

Study: Three-drug combination improves overall survival in patients with mCRC

The three-drug combination of encorafenib, binimetinib and cetuximab significantly improved overall survival (OS) in patients with BRAF-mutated metastatic colorectal cancer (mCRC), according to results of the BEACON CRC Phase III clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

30 Sep 2019

Cancer patients who miss an appointment more likely to die within 12 months of diagnosis

Cancer patients who miss an urgent referral appointment for their symptoms are 12% more likely to die within 12 months of diagnosis, a major new study has found.

12 Sep 2019

Liquid biopsies provide complete picture of genetic alterations linked to cancer drug resistance

Many patients see their tumors shrink in response to a drug, only to have them come back with a vengeance as they evolve to fend off the treatment. Oncologists want to be able to quickly detect cancer drug resistance as it emerges in their patients and identify another drug the tumors will still respond to.

10 Sep 2019

Gastrointestinal Cancer News and Research

Salk scientists uncover surprising role of tuft cells in pancreatitis

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Study provides new details about therapy-associated polyposis in childhood cancer survivors

Study reveals new mechanism involved in the pathogenesis of IBD

Cystic fibrosis carriers have higher risk for all CF-related conditions

Proton therapy reduces the relative risk of side effects for cancer patients

Artificial Intelligence (AI) in Cancer Care

Diet high in fiber and yogurt linked with reduced risk for lung cancer

Study represents a major step in seeking alternative cancer treatments for non-responders

New trial shows improved survival for patients with advanced colorectal BRAF-mutant cancer

Study: Three-drug combination improves overall survival in patients with mCRC

Cancer patients who miss an appointment more likely to die within 12 months of diagnosis

Liquid biopsies provide complete picture of genetic alterations linked to cancer drug resistance

MicroRNA methylation may be useful biomarker for early cancer diagnosis

Genetically altering protein in colon cancer cells may enhance efficacy of chemotherapy

Study shows synergistic effects of drugs that inhibit cell division in pancreatic cancer

New drug combinations and dosing schedules improve outlook in advanced colon cancer

Study suggests usefulness of more flexible dose of regorafenib to relieve side-effects in mCRC patients

Study finds link between poor oral health and increased risk of liver cancer

Identifying colorectal cancer subtypes in patients could help provide better care

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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