Gene Editing News and Research

RSS

Rentschler Biopharma licenses Horizon Discovery’s CHOSOURCE platform to complement cell line development offering for difficult-to-express proteins

Rentschler Biopharma SE, and Horizon Discovery, a leader in the application of gene editing, today announced the signing of a commercial license agreement.

From Revvity 19 May 2020

Mouse model helps track organism’s development from embryonic stage to adulthood

Scientists at the Stem Cell Research program at Boston Children's Hospital and Dana-Farber Cancer Institute/Harvard Medical School have devised a mouse model that lets researchers track every cell in the body, from the embryonic stage until adulthood.

15 May 2020

Ori Biotech and CellGenix to collaborate in order to promote innovation within closed-system cell and gene therapy manufacturing

Ori Biotech Ltd announced a partnership to achieve closed-system preparation and the addition of CellGenix media and growth factors within CGT manufacturing.

14 May 2020

OXGENE™ reports third consecutive year of 100% year on year revenue growth

OXGENE™ has more than doubled its annual revenue in the financial year just closed, in the third consecutive year of 100% year on year revenue growth.

From OXGENE 6 May 2020

Wyss Institute and Cytosurge collaborate to improve CRISPR multiplexing

Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Cytosurge AG, a company manufacturing unique high-precision nanotechnology instruments, announced that they will collaboratively investigate CRISPR-based approaches to more effectively introduce multiple edits into the genome of single cells, while minimizing CRISPR-related toxicity.

4 May 2020

Study: Unique glucose-sensing neurons in the brain prevent severe hypoglycemia

Low blood sugar levels, known as hypoglycemia, can be a life-threatening situation, especially for people with type 1 diabetes who rely on intensive insulin therapy to prevent blood sugar from going too high.

4 May 2020

Horizon Discovery extends coverage of OncoSpan reference standards to FFPE and Liquid Biopsy

Horizon Discovery Group plc, today announced it has added two new sample formats to its cell-based OncoSpan reference standards for cancer diagnostic assays.

From Revvity 29 Apr 2020

India to deploy homegrown tech against COVID-19

When India's 1.3 billion people come out of a 40-day lockdown on 3 May, imposed to contain the spread of COVID-19, they can hope that a battery of technologies that the government is readying to deploy against the contagious virus could offer them some protection.

28 Apr 2020

A new tool for developing gene therapies against cancer, genetic disorders, and blood diseases

A UCLA-led research team today reports that it has developed a new method for delivering DNA into stem cells and immune cells safely, rapidly and economically.

28 Apr 2020

Rice University wins prestigious grant to develop new therapies for sickle cell disease

A Rice University lab has won a prestigious National Institutes of Health grant to pursue gene-editing research it hopes will lead to a cure for sickle cell disease (SCD).

25 Apr 2020

New genome-editing techniques could make recombinant-protein drugs cheaper

The mammalian cell lines that are engineered to produce high-value recombinant-protein drugs also produce unwanted proteins that push up the overall cost to manufacture these drugs. These same proteins can also lower drug quality

24 Apr 2020

A new method to deliver therapeutic proteins inside the body

A new way to deliver therapeutic proteins inside the body uses an acoustically sensitive carrier to encapsulate the proteins and ultrasound to image and guide the package to the exact location required, according to Penn State researchers. Ultrasound then breaks the capsule, allowing the protein to enter the cell.

23 Apr 2020

Study: Patients’ genetically edited stem cells successfully reversed diabetes in mice

Using induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes called Wolfram syndrome, researchers transformed the human stem cells into insulin-producing cells and used the gene-editing tool CRISPR-Cas9 to correct a genetic defect that had caused the syndrome.

22 Apr 2020

Gene therapy could help treat glaucoma, study shows

A new study led by the University of Bristol has shown a common eye condition, glaucoma, could be successfully treated with a single injection using gene therapy, which would improve treatment options, effectiveness and quality of life for many patients.

21 Apr 2020

RIT researchers develop miniature lab device to detect bacteria, viruses

Engineering researchers developed a next-generation miniature lab device that uses magnetic nano-beads to isolate minute bacterial particles that cause diseases.

18 Apr 2020

Horizon Discovery offers rapid access to CHOSOURCE platform for development of COVID-19 therapies

Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation for cell line engineering, today announced special commercial licensing terms to facilitate rapid access to its cGMP-compliant CHOSOURCE platform for the development or production of therapeutic proteins, diagnostic assay components or vaccines relating to COVID-19.

16 Apr 2020

Researchers decode how immune sensor plays role in defending cells against intruders

Until now, the immune sensor TLR8 has remained in the shadows of science. A research team led by the University of Bonn has now discovered how this sensor plays an important role in defending human cells against intruders.

15 Apr 2020

CRISPR may help in kidney-transplants by detecting viruses

An exciting new study published in the journal Nature Biomedical Engineering in April 2020 reports excellent results with a new test for two common viruses that infect kidney transplant patients. The levels of these viruses shoot up during the acute phase of rejection.

13 Apr 2020

Researchers make breakthrough in unlocking genetic potential of ocean microbes

Researchers have made a breakthrough in developing gene-editing tools to improve understanding of an important ocean microbe.

6 Apr 2020

Research suggests an avenue to treat, prevent genetic disorders in the womb

New research led by hearing scientists at Oregon Health & Science University suggests an avenue to treat and prevent intractable genetic disorders before birth.