Gene Editing News and Research

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Scientists show way to edit genome of disease-carrying mosquitoes

Scientists at UC Berkeley and UC Riverside have demonstrated a way to edit the genome of disease-carrying mosquitoes that brings us closer to suppressing them on a continental scale.

28 Jun 2017

Stem cell therapy may harm heart disease patients, study finds

Patients with severe and end-stage heart failure have few treatment options available to them apart from transplants and "miraculous" stem cell therapy.

15 Jun 2017

Researchers use gene-editing technique to develop new screening tool for Parkinson's disease

A team of researchers at the University of Central Florida is using breakthrough gene-editing technology to develop a new screening tool for Parkinson's disease, a debilitating degenerative disorder of the nervous system.

5 Jun 2017

Study underlines significance of microglia for homeostasis in the brain

The role of microglial cells in neurodegenerative disease is not fully understood. But new results from researchers in Munich and Basel suggest that stimulation of this arm of the immune system might well delay the onset of such disorders.

2 Jun 2017

Scientists identify new gene that prompts muscle stem cells to fuse together

A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues.

1 Jun 2017

CRISPR may not be as foolproof as earlier believed – gene editing tech leads to unwanted mutations

CRISPR-Cas9 is a revolutionary new gene-editing technology that has been called “molecular scissors” and has been one of the handiest tools for genetic engineers in the recent times. It makes cutting and pasting gene sequences almost as easy as it sounds. CRISPR has been hailed as a breakthrough in genetic engineering.

30 May 2017

Gene editing technology can introduce hundreds of unintended mutations, study shows

As CRISPR-Cas9 starts to move into clinical trials, a new study published in Nature Methods has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome.

29 May 2017

Study reveals how enzyme allows brain tumors to grow despite harsh surroundings

All cancer tumors have one thing in common – they must feed themselves to grow and spread, a difficult feat since they are usually in a tumor microenvironment with limited nutrients and oxygen.

26 May 2017

Study finds two genetic variants linked to bicuspid aortic valve development

Researchers are working to determine why the aortic valve doesn't form correctly in patients with the most common congenital heart defect: bicuspid aortic valve.

25 May 2017

Pitt scientists discover genes responsible for severe congenital heart disease

The first known identification of two genes responsible for hypoplastic left heart syndrome (HLHS), a severe congenital heart defect, has been reported by researchers at the University of Pittsburgh School of Medicine.

22 May 2017

‘Disease in a dish’ model pinpoints how defects in blood-brain barrier can cause psychomotor disorder

Scientists for the first time have assembled a "disease in a dish" model that pinpoints how a defect in the blood-brain barrier can produce an incurable psychomotor disorder, Allan-Herndon-Dudley syndrome.

17 May 2017

Study shows first removal of HIV-1 replication using CRISPR/Cas9, gene editing technology

A new study published in the journal Molecular Therapy reveals that HIV DNA in the genome of living animals can be removed to eliminate further infection. While a permanent cure for infection caused by HIV remains a challenge due to the ability of the virus to hide away in latent reservoirs. The study team comprising Wenhui Hu, Kamel Khalili, Laura H. Carnell, and Won-Bin Young carried out an experiment on three different animal models.

4 May 2017

IU researchers develop new method to grow inner ear tissue from human stem cells

Researchers at Indiana University School of Medicine have successfully developed a method to grow inner ear tissue from human stem cells-; PhDa finding that could lead to new platforms to model disease and new therapies for the treatment of hearing and balance disorders.

3 May 2017

Study: New gene editing strategy effectively targets cancer-causing ‘fusion genes’ in mouse models

A novel gene therapy using CRISPR genome editing technology effectively targets cancer-causing "fusion genes" and improves survival in mouse models of aggressive liver and prostate cancers, University of Pittsburgh School of Medicine researchers report in a study published online today in Nature Biotechnology.

2 May 2017

New study shows that gene editing technology can shut down HIV-1 replication in animals

A permanent cure for HIV infection remains elusive due to the virus's ability to hide away in latent reservoirs. But now, in new research published in print May 3 in the journal Molecular Therapy, scientists at the Lewis Katz School of Medicine at Temple University and the University of Pittsburgh show that they can excise HIV DNA from the genomes of living animals to eliminate further infection.

2 May 2017

Actress Kiruna Stamell argues about gene editing with Dr Christopher Gyngell

Two papers published today by the Journal of the Royal Society of Medicine, debate gene editing and the health of future generations.

29 Apr 2017

Scientists rewire mouse stem cells to fight inflammation caused by arthritis

Using new gene-editing technology, researchers have rewired mouse stem cells to fight inflammation caused by arthritis and other chronic conditions.

28 Apr 2017

NETRF announces $4 million in collaborative grants to study neuroendocrine tumors

The Neuroendocrine Tumor Research Foundation today announced its largest research commitment ever -- $4 million in collaborative grants -- most from its new Accelerator Grants program to study neuroendocrine tumors, a widely misunderstood, commonly misdiagnosed cancer type, without adequately identified genomic drivers.

27 Apr 2017

New technique dramatically accelerates search for new cancer treatments

A new technique developed at the University of Virginia School of Medicine will let a single cancer research lab do the work of dozens, dramatically accelerating the search for new treatments and cures.

26 Apr 2017

Scientists use modern techniques to investigate how silver poisons pathogenic microbes

Silver and other metals have been used to fight infections since ancient times. Today, researchers are using sophisticated techniques such as the gene-editing platform Crispr-Cas9 to take a closer look at precisely how silver poisons pathogenic microbes-; and when it fails.