Gene Editing News and Research

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Scientists create new technique for studying how chlamydia interacts with immune system

Scientists at the Wellcome Trust Sanger Institute and their collaborators at the University of British Columbia have created an innovative technique for studying how chlamydia interacts with the human immune system.

25 Apr 2017

Researchers use gene-editing tool to restore visual function in mouse models of retinitis pigmentosa

Using the gene-editing tool CRISPR/Cas9, researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health, with colleagues in China, have reprogrammed mutated rod photoreceptors to become functioning cone photoreceptors, reversing cellular degeneration and restoring visual function in two mouse models of retinitis pigmentosa.

21 Apr 2017

Seeing genes inside living cells

For Mazhar Adli, the little glowing dots dancing about on the computer screen are nothing less than the fulfillment of a dream. Those fluorescent dots, moving in real time, are set to illuminate our understanding of the human genome, cancer and other genetic diseases in a way never before possible.

14 Apr 2017

Researchers correct Duchenne muscular dystrophy using gene-editing alternative

Using the new gene-editing enzyme CRISPR-Cpf1, researchers at UT Southwestern Medical Center have successfully corrected Duchenne muscular dystrophy in human cells and mice in the lab.

13 Apr 2017

Scientists discover promising target to treat highly aggressive brain tumor in infants

Using state-of-the-art gene editing technology, scientists from Ann & Robert H. Lurie Children's Hospital of Chicago have discovered a promising target to treat atypical teratoid/rhabdoid tumor (AT/RT) – a highly aggressive and therapy resistant brain tumor that mostly occurs in infants.

11 Apr 2017

TSRI researchers reveal how viruses incapacitate bacterial defense system

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided "immune system" called CRISPR-Cas.

28 Mar 2017

Astrocytes prove to be surprisingly vital players in the body's clock

Until recently, work on biological clocks that dictate daily fluctuations in most body functions, including core body temperature and alertness, focused on neurons, those electrically excitable cells that are the divas of the central nervous system.

25 Mar 2017

Major grant funds research effort that seeks to understand complexity of invasive cancer

A $9.5 million, five-year grant from the National Cancer Institute (NCI) will fund an intensive multidisciplinary research effort that seeks to better understand how cancer cells reach an aggressive state and begin to damage surrounding tissue.

25 Mar 2017

Researchers develop new method that uses gene editing to find cancer's weak spots

Genetic mutations that cause cancer also weaken cancer cells, creating an opportunity for researchers to develop drugs that will selectively kill them, while sparing normal cells.

20 Mar 2017

Graduate students develop novel microfluidic platform for monitoring single cell-level electroporation

Graduate students Mingde 'Jack' Zheng and Joseph Sherba have developed a novel, microfluidic platform for monitoring electroporation and molecular delivery at the single cell-level as part of a collaborative re-search team led by Professors Jeffrey Zahn and David Shreiber in the Department of Biomedical Engineer-ing and Professors Hao Lin and Jerry Shan in the Department of Mechanical and Aerospace Engineering at Rutgers,

3 Mar 2017

Study establishes ENL protein as potential drug target for acute myeloid leukemia

Anyone who uses an employee badge to enter a building may understand how a protein called ENL opens new possibilities for treating acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells and the second most common type of leukemia in children and adults.

2 Mar 2017

Scientists engineer smallest CRISPR-Cas9 system to date

Scientists at the Center for Genome Engineering, within the Institute for Basic Science0, in collaboration with KIM Eunji and KIM Jeong Hun have engineered the smallest CRISPR-Cas9 to date, delivered it to the muscle cells and in the eyes of mice via adeno-associated viruses and used it to modify a gene causing blindness.

21 Feb 2017

New imaging technology catches DNA naturally fluorescing

Many of the secrets of cancer and other diseases lie in the cell's nucleus. But getting way down to that level -- to see and investigate the important genetic material housed there -- requires creative thinking and extremely powerful imaging techniques.

17 Feb 2017

IBS scientists modify fat content in soybean oil using new CRISPR-Cpf1 technology

A team from the Center for Genome Engineering, within the Institute for Basic Research (IBS), succeeded in editing two genes that contribute to the fat contents of soybean oil using the new CRISPR-Cpf1 technology: an alternative of the more widely used gene editing tool CRISPR-Cas9. The results of this new plant gene editing method, applied to soybeans and wild tobacco genes, are published in Nature Communications.

16 Feb 2017

Gene Editing News and Research

Scientists create new technique for studying how chlamydia interacts with immune system

Researchers use gene-editing tool to restore visual function in mouse models of retinitis pigmentosa

Seeing genes inside living cells

Researchers correct Duchenne muscular dystrophy using gene-editing alternative

Scientists discover promising target to treat highly aggressive brain tumor in infants

TSRI researchers reveal how viruses incapacitate bacterial defense system

Astrocytes prove to be surprisingly vital players in the body's clock

Major grant funds research effort that seeks to understand complexity of invasive cancer

Researchers develop new method that uses gene editing to find cancer's weak spots

Graduate students develop novel microfluidic platform for monitoring single cell-level electroporation

Study establishes ENL protein as potential drug target for acute myeloid leukemia

Scientists engineer smallest CRISPR-Cas9 system to date

New imaging technology catches DNA naturally fluorescing

IBS scientists modify fat content in soybean oil using new CRISPR-Cpf1 technology

Specific genetic errors that trigger congenital heart disease can be reproduced in common fruit fly

UT Southwestern scientists discover gene that protects gut from IBD

Scientists develop unique method to fix genes in living organisms

NTNU researcher uses big data to understand how immune system responds to viral attack

ACMG issues new Points to Consider statement on potential clinical application of genome editing

GUMC researchers describe lab technique to fill gaps in clinical care and research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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