Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

UPC develops new system for electroporation of cell cultures

Researchers from the Polytechnic University of Catalonia have developed a technique that improves and cuts the cost of a technique called electroporation, which involves opening pores in cell membranes using an electric field to introduce substances like drugs and DNA. Current methods are aggressive and expensive whereas the new system manages to apply low voltage electroporation with a small printed circuit board, which costs less than a Euro per unit and does not damage cells.

11 Feb 2013

NIH researchers review research on dog cranium development

Man's best friend may touch our hearts with their empathy, companionship, playfulness and loyalty, and they may also lead us to a deeper understanding of our heads.

11 Feb 2013

Highlights for Feb. 2013 issue of Genetics journal

Listed below are the selected highlights for the February 2013 issue of the Genetics Society of America's journal, Genetics.

10 Feb 2013

CtBP may play a key role in aggressive forms of breast cancer

A protein associated with conditions of metabolic imbalance, such as diabetes and obesity, may play a role in the development of aggressive forms of breast cancer, according to new findings by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, and their colleagues.

9 Feb 2013

Basis of antidepressant drugs and electroconvulsive therapy found

Through a series of investigations in mice and humans, Johns Hopkins researchers have identified a protein that appears to be the target of both antidepressant drugs and electroconvulsive therapy. Results of their experiments explain how these therapies likely work to relieve depression by stimulating stem cells in the brain to grow and mature.

7 Feb 2013

Sangamo BioSciences fourth quarter revenues increase to $8.9 million

Sangamo BioSciences, Inc. today reported fourth quarter and full year 2012 financial results and accomplishments.

7 Feb 2013

Genomic Health fourth quarter total revenue increases to $60.4 million

Genomic Health, Inc. today reported financial results and business progress for the quarter and year ended December 31, 2012.

6 Feb 2013

Researchers pinpoint how vitamin D3 and omega-3 may boost immunity to help fight Alzheimer's

A team of academic researchers has pinpointed how vitamin D3 and omega-3 fatty acids may enhance the immune system's ability to clear the brain of amyloid plaques, one of the hallmarks of Alzheimer's disease.

5 Feb 2013

MammaPrint breast cancer test can help women avoid chemotherapy

The MammaPrint breast cancer test can dramatically reduce the number of women who need to undergo chemotherapy to treat the disease, according to a newly published study.

5 Feb 2013

An Introduction to the LV200 Bioluminescence Microscope

News-Medical speaks to Robert Schmalzigaug to explore the field of bioluminescence imaging and the applications of the LV200 microscope.

From Evident Corporation - Life Sciences 5 Feb 2013

Scientists discover new evidence for role of epigenetic changes on premature aging diseases

Scientists at the Bellvitge Biomedical Research Institute in Barcelona, Spain have found new evidence for the role of epigenetic changes (those heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence) on premature aging diseases.

1 Feb 2013

Tributyltin exposure may cause ‘transgenerational obesity’

Research shows that offspring of mice exposed to low doses of the chemical tributyltin, used in paints, plastics, and other consumer products, have greater than normal body fat, liver fat, and fat-specific gene expression.

30 Jan 2013

New study may help treat patients with multiple myeloma

A study led by Robert G. Hawley, Ph.D., professor and chair of the department of anatomy and regenerative biology at the George Washington University (GW) School of Medicine and Health Sciences (SMHS), may help predict which patients with multiple myeloma will respond better to certain treatments.

25 Jan 2013

Researchers find new genetic differences in human hearts

Healthy men and women show little difference in their hearts, except for small electrocardiographic disparities. But new genetic differences found by Washington University in St. Louis researchers in hearts with disease could ultimately lead to personalized treatment of various heart ailments.

25 Jan 2013

Mice exposed to BPA exhibit spontaneous activity, have leaner body mass

Female mice exposed to Bisphenol A through their mother's diet during gestation and lactation were found to be hyperactive, exhibit spontaneous activity and had leaner body mass than those not exposed to the chemical, researchers at the University of Michigan School of Public Health have discovered.

25 Jan 2013

Early-life exposure to TBT chemical can cause obesity

Exposing pregnant mice to low doses of the chemical tributyltin (TBT) - which was used in marine antifouling paints and is used as an antifungal agent in some paints, certain plastics and a variety of consumer products - can lead to obesity for multiple generations without subsequent exposure, a UC Irvine study has found.

25 Jan 2013

Gastrointestinal Cancers Symposium to be held from Jan. 24-26 in San Francisco, CA

New research into the treatment and prognosis of gastrointestinal cancers was released today in advance of the tenth annual Gastrointestinal Cancers Symposium being held January 24-26, 2013, at The Moscone West Building in San Francisco, CA.

24 Jan 2013

Study may help predict which multiple myeloma patients will respond better to certain treatments

24 Jan 2013

Scientists identify consistent epigenetic signatures in men with metastatic prostate cancer

In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic "signatures" across all metastatic tumors in each patient.

23 Jan 2013

Salk Institute to establish Helmsley Center for Genomic Medicine

The Salk Institute for Biological Studies has received a $42 million gift-the largest in the Institute's history-to establish the Helmsley Center for Genomic Medicine (HCGM), a research center dedicated to decoding the common genetic factors underlying many complex chronic human diseases.

23 Jan 2013