Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Benitec strengthens patent position in RNAi

Benitec Limited (ASX: BLT), (PINK:BNIKF), a world leader in expressed gene silencing for human therapeutics, is pleased to announce that the United States Patent and Trademark Office (USPTO) has today indicated that it is issuing the Re-examination Certificate, the formal final step in the USPTO’s confirmation of patentability of claims in the key ‘099 Graham Patent [US Patent No. 6,573,099] "Genetic Constructs for Delaying or Repressing the Expression of a Target Gene", the wide-ranging platform technology patent covering the use of expressed RNA interference (RNAi) in human therapeutic applications.

17 Feb 2011

Researchers find blue-green algae may be responsible for producing estrogen-like compound in water

University of Tennessee, Knoxville, researchers have found that blue-green algae may be responsible for producing an estrogen-like compound in the environment which could disrupt the normal activity of reproductive hormones and adversely affect fish, plants and human health.

17 Feb 2011

Unrecognized substances released by algae blooms may act as endocrine disruptors

Scientists are reporting for the first time that previously unrecognized substances released by algae blooms have the potential to act as endocrine disruptors, which can interfere with the normal activity of reproductive hormones. The effect is not caused by microcystin toxins, long recognized as potentially harmful to humans and aquatic animals, but as yet unidentified substances.

17 Feb 2011

Genomic Health to present prostate cancer studies at ASCO Genitourinary Cancer Symposium

Genomic Health, Inc. today announced the presentation of two studies at the American Society of Clinical Oncology® (ASCO®) Genitourinary (GU) Cancer Symposium, including complete results from its prostate cancer gene identification study, which identified 295 genes strongly associated with clinical recurrence following radical prostatectomy with great consistency across multiple tumor samples examined in each patient.

17 Feb 2011

Molecular explanation to higher tendency for autism among males

George Washington University researcher, Dr. Valerie Hu, Professor of Biochemistry and Molecular Biology, and her team at the School of Medicine and Health Sciences, have found that male and female sex hormones regulate expression of an important gene in neuronal cell culture through a mechanism that could explain not only higher levels of testosterone observed in some individuals with autism, but also why males have a higher incidence of autism than females.

17 Feb 2011

New method may eliminate colonoscopies

Nobody enjoys colonoscopies, including mice. University of Missouri researchers are excited about the potential of using genetic biomarkers to predict colon cancer caused by inflammation. A new method developed at the MU Research Animal Diagnostic Laboratory (RADIL) could eventually lead to a method that might eliminate colonoscopies altogether.

17 Feb 2011

IMGM Labs purchases Fluidigm Access Array system to use in re-sequencing applications

IMGM Laboratories GmbH has purchased a Fluidigm Access Array System to use in its development and validation of targeted re-sequencing applications services.

16 Feb 2011

WaferGen offers SNP Genotyping screening with new SmartChip PCR System

WaferGen Biosystems, Inc. a leading developer of state-of-the-art genomic analysis systems, today announced that it is offering an early access program for high-throughput Single Nucleotide Polymorphism Genotyping through its new SmartChip Real-Time PCR System.

16 Feb 2011

Research: MEF2D protein in mitochondria appears to contribute early steps in Parkinson's disease

For the last several years, neurologists have been probing a connection between Parkinson's disease and problems with mitochondria, the miniature power plants of the cell.

15 Feb 2011

Researchers use computers to capture chemical signal structure that triggers metastatic cancer

In cancer and other pathological diseases, researchers are discovering that packaging is important: specifically, how DNA - about two meters long when unwound and stretched - coils up and compacts neatly inside the nucleus of a cell.

15 Feb 2011

New England Biolabs adds OneTaq and OneTaq Hot Start DNA Polymerases to line of PCR reagents

New England Biolabs has expanded its line of PCR reagents to include OneTaq™ and OneTaq Hot Start DNA Polymerases. Optimized blends of Taq and Deep Vent® DNA Polymerases, these new products offer robust amplification across a wide range of templates, including routine, AT-rich and GC-rich amplicons.

From New England Biolabs 15 Feb 2011

Gene-transfer system may control mosquito-borne diseases without pesticides

Scientists have modeled a system that may be used to control mosquitoes and the diseases they transmit, without the use of pesticides. In the proposed system, mosquitoes are engineered to carry two genes. The first gene causes males to transmit a toxin to females through their semen. The second gene, when expressed in females, makes them immune to this toxin.

14 Feb 2011

NIH awards Geospiza phase II SBIR grant to develop new DNA variant application for GeneSifter platform

Geospiza, Inc. the market leading developer of the GeneSifter® software platform for genetic analysis, today announced that the National Human Genome Research Institute of the National Institutes of Health has awarded the company a phase II SBIR grant to collaborate with researchers at Weil Cornell Medical College, Mayo Clinic to develop a new application that quickly identifies and visualizes DNA sequence variations found when comparing normal and cancer tissues using Geospiza's GeneSifter cloud computing platform.

11 Feb 2011

Athersys' MultiStem cell therapy provides multiple benefits in preclinical models of ischemic stroke

Medical researchers from The University of Texas Health Science Center at Houston (UTHealth) presented new research results at the American Heart Association International Stroke Conference that demonstrated how MultiStem-, a novel stem cell therapy being developed by Athersys, Inc. provided multiple benefits when administered in preclinical models of ischemic stroke.

11 Feb 2011

Presence of jumping genes, amplified oncogenes may be key to tumor progression: Researchers

The Massachusetts General Hospital research team that first discovered tumor-associated RNA in tiny membrane-enclosed sacs released into the bloodstream by cancer cells has now found that these microvesicles also contain segments of tumor DNA, including retrotransposons - also called "jumping genes" - that copy and insert themselves into other areas of the genome.

10 Feb 2011

Men with high levels of CCP genes more likely to have fatal form of prostate cancer

A genetic pattern could predict how aggressive prostate cancer is before treatment, and whether the disease will come back in men who have already been treated, according to research published1 in the Lancet Oncology.

9 Feb 2011

Urocortin system plays central role in regulating stress responses

Post-traumatic stress disorder can affect soldiers after combat or ordinary people who have undergone harrowing experiences. Of course, feelings of anxiety are normal and even desirable - they are part of what helps us survive in a world of real threats. But no less crucial is the return to normal - the slowing of the heartbeat and relaxation of tension - after the threat has passed.

9 Feb 2011

Study identifies genetic variation linked with increased risk of major depression

Numerous studies have shown that the brain molecule neuropeptide Y (NPY) helps to restore calm after stressful events. A team of University of Michigan-led researchers has now found that people whose genes predispose them to produce lower levels of NPY are more responsive to negative stimuli in key brain circuits related to emotion - and are therefore less resilient in the face of stress and may be at higher risk for developing a major depressive disorder.

8 Feb 2011

XDx and LabCorp enter non-hospital provider agreement for AlloMap molecular expression tests

XDx, Inc., a molecular diagnostics company focused on noninvasive gene expression tests to monitor immune-mediated conditions, today announced that it has entered into a multi-year agreement with Laboratory Corporation of America Holdings to provide heart transplant patients eligible for XDx's AlloMap® test with the convenience of having their blood drawn at participating LabCorp sites across the United States.

7 Feb 2011

Human Vaccines journal publishes paper on Inovio's new DNA vaccine delivery technology

Inovio Pharmaceuticals, Inc., a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today that its new generation DNA vaccine delivery technology, which provides the powerful enabling capabilities of electroporation without contacting the skin, is highlighted in a paper published in the scientific journal Human Vaccines.

7 Feb 2011

Gene Expression News and Research

Further Reading

Benitec strengthens patent position in RNAi

Researchers find blue-green algae may be responsible for producing estrogen-like compound in water

Unrecognized substances released by algae blooms may act as endocrine disruptors

Genomic Health to present prostate cancer studies at ASCO Genitourinary Cancer Symposium

Molecular explanation to higher tendency for autism among males

New method may eliminate colonoscopies

IMGM Labs purchases Fluidigm Access Array system to use in re-sequencing applications

WaferGen offers SNP Genotyping screening with new SmartChip PCR System

Research: MEF2D protein in mitochondria appears to contribute early steps in Parkinson's disease

Researchers use computers to capture chemical signal structure that triggers metastatic cancer

New England Biolabs adds OneTaq and OneTaq Hot Start DNA Polymerases to line of PCR reagents

Gene-transfer system may control mosquito-borne diseases without pesticides

NIH awards Geospiza phase II SBIR grant to develop new DNA variant application for GeneSifter platform

Athersys' MultiStem cell therapy provides multiple benefits in preclinical models of ischemic stroke

Presence of jumping genes, amplified oncogenes may be key to tumor progression: Researchers

Men with high levels of CCP genes more likely to have fatal form of prostate cancer

Urocortin system plays central role in regulating stress responses

Study identifies genetic variation linked with increased risk of major depression

XDx and LabCorp enter non-hospital provider agreement for AlloMap molecular expression tests

Human Vaccines journal publishes paper on Inovio's new DNA vaccine delivery technology

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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