Gene Transfer News and Research

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Gene Transfer is the insertion of genetic material into a cell.

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

A fruit fly genome is not a just made up of fruit fly DNA – at least for one fruit fly species. New research from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) shows that one fruit fly species contains whole genomes of a kind of bacteria, making this finding the largest bacteria-to-animal transfer of genetic material ever discovered. The new research also sheds light on how this happens.

3 Aug 2022

Investigating an effective linear deoxyribonucleic acid COVID-19 vaccine option for domestic cats

In a new study, investigators studied a linear deoxyribonucleic acid (linDNA) SARS-CoV-2 vaccine option in felines.

27 Jul 2022

Gut-lung axis: Using commensal bacteria to reinforce mucosal immunity

A recent study discusses the use of commensal bacteria in the gut and/or respiratory tract to deliver viral antigens to the host, thus acting as vaccines

19 Jul 2022

Researchers gain unexpected insights into activation mechanism of flaviviruses

A collaboration between researchers at the Center for Virology of the Medical University of Vienna and the Pasteur Institute in Paris has provided unexpected insights into the atomic interactions of the tick-borne encephalitis (TBE) virus in infected cells.

13 Jul 2022

Review sheds light on the emergence and detection of antibiotic resistance in bioaerosols

Bioaerosols, or airborne biological particles containing viruses, fungal spores, bacteria, and pollen, play a key role in public health. Antibiotic resistance (AR), caused by antibiotic resistance genes (ARGs), could potentially cause global public health crises owing to horizontal gene transfer between same or similar bacterial bioaerosols.

30 Jun 2022

First open-source program can improve detection and tracking of pathogenic DNA sequences

It's a given that certain bacteria and viruses can cause illness and disease, but the real culprits are the sequences of concern that lie within the genomes of these microbes.

21 Jun 2022

Researchers reveal mechanism for spread of antibiotic resistance among bacteria

A bacteria calledStaphylococcusaureusis widespread and generally harmless, but can cause infections known as "opportunistic infections".

13 May 2022

Study suggests SARS-CoV-2 is undergoing evolutionary changes at the functional RNA level in addition to the amino acid level

Researchers demonstrated SARS-CoV-2 evolution at the transcriptional level.

22 Apr 2022

Synthetic viral vector and surgical approach enable efficient gene transfer into the inner ear of primates

A synthetic viral vector and a novel surgical approach developed at Mass Eye and Ear has enabled efficient gene transfer into the inner ear of nonhuman primates, a research team working towards the development of effective treatments for hearing loss and vestibular disorders has reported.

15 Mar 2022

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

Researchers demonstrate enhanced loss-of-function editing of CRISPR/Cas9 in human cells.

14 Mar 2022

New approach to CAR T-cell therapy for B-cell cancers triples the targeted antigens on cancer cells

Researchers at University Hospitals Seidman Cancer Center and Case Western Reserve University have developed a novel approach to chimeric antigen receptor (CAR) T-cell therapy for B-cell cancers that triples the targeted antigens on cancer cells – a "back up" approach that promises to greatly reduce the potential for antigen escape currently found in CAR T therapies that solely target CD19.

2 Feb 2022

Horizontal gene transfer between viruses and hosts plays a major role in driving evolution

The first comprehensive analysis of viral horizontal gene transfer (HGT) illustrates the extent to which viruses pick up genes from their hosts to hone their infection process, while at the same time hosts also co-opt useful viral genes.

5 Jan 2022

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

A new review article determines the role of UV disinfection for nosocomial transmission of COVID-19 and other infectious diseases.

22 Nov 2021

New trial demonstrates stable coagulation factor VIII in hemophilia A patients after gene therapy

A novel gene therapy for hemophilia A led to sustained expression of the clotting factor those patients lack, resulting in a reduction – or in some cases complete elimination – of painful and potentially life-threatening bleeding events, according to a new study led by researchers at Children's Hospital of Philadelphia.

18 Nov 2021

Study finds immunity against SARS-CoV-2 delta variant waned after BNT162b2 vaccine second dose

Researchers from Israel have investigated the possibility that vaccine-induced immunity reduces over time and potential causes and risk factors.

29 Oct 2021

Study finds one mRNA vaccine dose after SARS-CoV-2 infection produces highest neutralizing antibody titers

Researchers investigated the neutralizing antibody response that different mRNA vaccines induce in both previously convalescent and SARS-CoV-2 naïve individuals.

28 Oct 2021

Machine learning approach effective in predicting antibiotic resistance spread

Genes aren't only inherited through birth. Bacteria have the ability to pass genes to each other, or pick them up from their environment, through a process called horizonal gene transfer, which is a major culprit in the spread of antibiotic resistance.

22 Oct 2021

Gene therapy strategy against Angelman syndrome shows early promise

Scientists at the UNC School of Medicine have reported in the journal JCI Insight encouraging early tests of a gene therapy strategy against Angelman syndrome, a neurodevelopmental disorder that features poor muscle control and balance, hard-to-treat epilepsy, and intellectual disabilities.

22 Oct 2021

Development of a safe and effective COVID-19 nanoparticle vaccine

Researchers from ReVacc scientific have attempted to demonstrate the effectiveness of a new vaccine, REVC-128, two weeks post-administration.

22 Oct 2021

How can framing COVID-19 vaccine side-effects affect an individual's willingness to be vaccinated?

Researchers from the University of Munich have investigated how framing vaccine side-effects can affect an individual's willingness to be vaccinated.

18 Oct 2021

Gene Transfer News and Research

Further Reading

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

Investigating an effective linear deoxyribonucleic acid COVID-19 vaccine option for domestic cats

Gut-lung axis: Using commensal bacteria to reinforce mucosal immunity

Researchers gain unexpected insights into activation mechanism of flaviviruses

Review sheds light on the emergence and detection of antibiotic resistance in bioaerosols

First open-source program can improve detection and tracking of pathogenic DNA sequences

Researchers reveal mechanism for spread of antibiotic resistance among bacteria

Study suggests SARS-CoV-2 is undergoing evolutionary changes at the functional RNA level in addition to the amino acid level

Synthetic viral vector and surgical approach enable efficient gene transfer into the inner ear of primates

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

New approach to CAR T-cell therapy for B-cell cancers triples the targeted antigens on cancer cells

Horizontal gene transfer between viruses and hosts plays a major role in driving evolution

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

New trial demonstrates stable coagulation factor VIII in hemophilia A patients after gene therapy

Study finds immunity against SARS-CoV-2 delta variant waned after BNT162b2 vaccine second dose

Study finds one mRNA vaccine dose after SARS-CoV-2 infection produces highest neutralizing antibody titers

Machine learning approach effective in predicting antibiotic resistance spread

Gene therapy strategy against Angelman syndrome shows early promise

Development of a safe and effective COVID-19 nanoparticle vaccine

How can framing COVID-19 vaccine side-effects affect an individual's willingness to be vaccinated?

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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