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Researchers identify a ‘gene module’ involved in both depression and cardiovascular disease

Depression and cardiovascular disease (CVD) are serious concerns for public health. Approximately 280 million people worldwide have depression, while 620 million people have CVD. It has been known since the 1990s that the two diseases are somehow related.

25 Apr 2024

Meta-analysis reveals drivers of antibiotic resistance in infants

A meta-analysis of genetic studies analyzing the microbiota (bacteria in the gut) of 1,275 infants from 10 countries finds that cesarean delivery and antibiotic use are driving the increase of antibiotic resistance genes load among infants, according to new research being presented at this year's ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April).

24 Apr 2024

Breast cancer survivors at higher risk of developing second cancers

Survivors of breast cancer are at significantly higher risk of developing second cancers, including endometrial and ovarian cancer for women and prostate cancer for men, according to new research studying data from almost 600,000 patients in England.

24 Apr 2024

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

A novel diagnostic model using machine learning (ML).

24 Apr 2024

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.

24 Apr 2024

Neurons re-entering cell cycle succumb to senescence in neurodegenerative diseases

Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this re-entry is more common in Alzheimer's disease, according to a new study published April 9th in the open-access journal PLOS Biology by Kim Hai-Man Chow and colleagues at the Chinese University of Hong Kong.

23 Apr 2024

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

A new $4.8 million grant will support researchers from Indiana University School of Medicine and the Medical Research Council Laboratory of Molecular Biology to study how human neurodegenerative diseases are affected by the misfolding of the protein TDP-43.

23 Apr 2024

Study identifies molecular pathway in liver cancer development

As a malignant disease of the liver cells, hepatocellular carcinoma (HCC) is one of the main causes of cancer-related deaths.

23 Apr 2024

The relationship between calcium consumption at various times of the day and cardiovascular disease

The quantity of calcium consumed at breakfast and dinner was associated with cardiovascular disease (CVD).

23 Apr 2024

Shared gene module links depression and cardiovascular disease

23 Apr 2024

University of Arizona researchers awarded $1.8M grant to investigate HPV's cellular invasion

Researchers at the University of Arizona College of Medicine – Tucson were awarded a $1.8 million grant by the National Institute of General Medical Sciences, a division of the National Institutes of Health, to learn how human papillomavirus makes its way to a cell's nucleus.

22 Apr 2024

Natural obesity fighters: How coffee, tea, and cocoa combat weight gain

A review in Current Research in Food Science explores how bioactive compounds in coffee, tea, and cocoa combat obesity by inhibiting white adipogenesis and promoting brown adipogenesis and lipolysis.

22 Apr 2024

Young mouse plasma found to reverse aging in older mice

Researchers demonstrate that small extracellular vesicles (sEVs) from young mice plasma can reverse aging effects in older mice by enhancing mitochondrial function and energy metabolism.

22 Apr 2024

New research identifies risk factors for dilated cardiomyopathy in genetic carriers

Dilated cardiomyopathy is the most frequent cause of heart failure in young people and is the leading cause of heart transplantation. In this disease, the heart enlarges and reduces its capacity to pump blood. People with dilated cardiomyopathy are at high risk for arrhythmias and sudden death.

22 Apr 2024

Exploring serine and glycine metabolism in hepatocellular carcinoma

Targeted therapy and immunotherapy have emerged as treatment options for hepatocellular carcinoma (HCC) in recent years. The significance of serine and glycine metabolism in various cancers is widely acknowledged.

22 Apr 2024

Insightful review explores alcohol-related liver cancer pathogenesis

While heavy drinking is a well-established risk factor for liver cancer, the specific mechanisms by which alcohol contributes to A-HCC remain unclear.

22 Apr 2024

Study links air pollution to increased colorectal cancer risk through DNA changes

Researchers reveal how air pollution increases colorectal cancer (CRC) risk through epigenetic changes, using a large-scale study and Mendelian randomization to demonstrate ambient pollution’s impact on CRC mortality and incidence in China.

21 Apr 2024

UC Riverside nematologist receives NIH award to study parasite-host interactions

To study how parasites evolve to break the defenses of their hosts, the National Institutes of Health has granted UC Riverside nematologist Simon "Niels" Groen a $1.9 million Outstanding Investigator Award.

18 Apr 2024

UCSF study identifies cells responsible for cough reflex

When a mouthful of water goes down the wrong pipe – heading toward a healthy person’s lungs instead of their gut – they start coughing uncontrollably.

18 Apr 2024

Researchers receive NIH grant to help develop gene therapy for HIV

Researchers at Washington University School of Medicine in St. Louis have received a $6.2 million grant from the National Institutes of Health (NIH) to develop a gene therapy that would modify the immune system's B cells to spur them to produce broadly neutralizing antibodies against HIV.

18 Apr 2024

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Genes News and Research

Researchers identify a ‘gene module’ involved in both depression and cardiovascular disease

Meta-analysis reveals drivers of antibiotic resistance in infants

Breast cancer survivors at higher risk of developing second cancers

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Neurons re-entering cell cycle succumb to senescence in neurodegenerative diseases

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

Study identifies molecular pathway in liver cancer development

The relationship between calcium consumption at various times of the day and cardiovascular disease

Shared gene module links depression and cardiovascular disease

University of Arizona researchers awarded $1.8M grant to investigate HPV's cellular invasion

Natural obesity fighters: How coffee, tea, and cocoa combat weight gain

Young mouse plasma found to reverse aging in older mice

New research identifies risk factors for dilated cardiomyopathy in genetic carriers

Exploring serine and glycine metabolism in hepatocellular carcinoma

Insightful review explores alcohol-related liver cancer pathogenesis

Study links air pollution to increased colorectal cancer risk through DNA changes

UC Riverside nematologist receives NIH award to study parasite-host interactions

UCSF study identifies cells responsible for cough reflex

Researchers receive NIH grant to help develop gene therapy for HIV

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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