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New findings show why some people suffer from high levels of triglycerides

New findings reported in the July issue of Cell Metabolism, a Cell Press publication, are offering new leads as to why some people might suffer from high levels of triglycerides. High triglycerides are a risk factor for atherosclerosis and cardiovascular disease. They can also lead to inflammation of the pancreas, the researchers said.

8 Jul 2010

Olaparib shows promising results against inherited forms of breast and ovarian cancer

Olaparib, a new type of experimental drug called a PARP inhibitor, has shown promising results against inherited forms of breast and ovarian cancer in two small clinical trials led by scientists at the Breakthrough Breast Cancer Research Unit at King's College London.

8 Jul 2010

Rutgers researchers report genetic coding responsible for making QPM kernels sturdy

Rutgers researchers have discovered the basis for what makes corn kernels hard, a quality that allows corn to be easily harvested, stored and transported. The findings could lead to better hybrids and increase the supply for people in developing countries who rely on it as a nutritional staple.

7 Jul 2010

Scientists identify potential disease genes in humans and mice

An international consortium of scientists of Helmholtz Zentrum München and the University of Toronto has identified previously unknown potential disease genes in humans and mice. Genes on the X chromosome, which regulate embryonic development, are the focus of the current publication in the renowned journal Genome Research. Men have only one X chromosome, and therefore mutations on this chromosome disproportionately affect males, frequently leading to serious diseases such as hemophilia, muscular dystrophy and mental retardation.

7 Jul 2010

MJFF announces $1.1M for projects to develop biomarker candidates for PD

The Michael J. Fox Foundation for Parkinson's Research today announced nearly $1.1 million for projects aimed at advancing the development of leading biomarker candidates for Parkinson's disease. The discovery and validation of biomarkers is of critical importance to increasing the speed and efficiency of PD therapeutic development, allowing scientists and clinicians to more accurately identify appropriate subjects for clinical studies, measure disease progression and monitor treatment effects in clinical trials.

7 Jul 2010

Study shows gene-environment interaction in congenital heart disease

A pregnant mother's diet may be able to interact with the genes her unborn child inherits and influence the type or severity of birth defect according to research funded by the Wellcome Trust and the British Heart Foundation. The study, published in the journal Human Molecular Genetics, suggests that mothers who eat a high fat diet before and through pregnancy could be inadvertently putting the health of their offspring at risk.

7 Jul 2010

TGen develops G-SQZ technique for genomic data processing

A new computer data compression technique called Genomic SQueeZ, developed by the Translational Genomics Research Institute, will allow genetic researchers and others to store, analyze and share massive volumes of data in less space and at lower cost.

7 Jul 2010

Slow rate of living and reduced energy metabolism is sufficient to increase longevity: Study

Don't put down the red wine and vitamins just yet, but if you're taking antioxidants because you hope to live longer, consider this: a new study published in the June 2010 issue of the journal GENETICS casts doubt on the theory that oxidative stress to our tissues shortens lifespan. That's because researchers from McGill University in Canada have identified mutations in 10 different genes of worms (genes believed to have counterparts in humans) that extend their lifespan without reducing the level of oxidative stress the worms suffer.

7 Jul 2010

Study finds additional targets for new therapies to treat advanced prostate cancer patients

In its early stages, prostate cancer requires androgens (hormones that promote the development and maintenance of male sex characteristics) for growth, and current first-line therapies target the receptor for these hormones to slow cancer's development and spread.

7 Jul 2010

Scientists discover nanoparticle to deliver DNA with minimum toxic effect

In lab experiments, the researchers have found that this device, a vector, is able to deliver DNA deeply enough into a cell to allow genetic material to be activated - a critical step in gene therapy. This vector is between 2 - and 10 times more effective than other experimental materials, according to the research.

7 Jul 2010

Hope for ovarian cancer patients not responding to conventional chemotherapy

Investigators at the Translational Genomics Research Institute (TGen) have discovered a way that may help ovarian cancer patients who no longer respond to conventional chemotherapy.

6 Jul 2010

Transplanted beta cells protect themselves by adapting to their new homes

For transplanted beta cells, life is tough. Not only are the insulin-producing cells in a stranger's body, tucked into the liver rather than the pancreas, they are a bit short on oxygen and blood, and they are often exposed to raised levels of glucose.

3 Jul 2010

Mount Sinai Hospital researchers discover new insights into genesis of stem cells

Mount Sinai Hospital researchers including Drs. Andras Nagy and Jeff Wrana have discovered new insights into the genesis of stem cells, which will improve the efficiency of stem cell creation for use in tissue regeneration and in the development of new drugs.

3 Jul 2010

IRSF reports record turn-out at 11th Annual Rett syndrome Symposium

IRSF's 11th Annual Rett syndrome Symposium held June 27, 28, and 29 in Leesburg, Virginia brought together leading scientists and researchers in the fields of neurobiology from around the globe who are attempting to demystify Rett syndrome. About 25 presenters led a day and a half of in-depth sessions attended by nearly 150 investigators and scientists, volunteers, families affected by the disease and IRSF staff.

3 Jul 2010

Study finds EPB41L3 'protector gene' inactivated in 65% of ovarian cancers

A new gene that normally protects against ovarian cancer is switched-off in two-thirds of cases of the disease, reveals a study published in the journal Neoplasia today.

3 Jul 2010

Further analysis on Bcl11b gene and T-cell behaviouur from Caltech Biologists

When does a cell decide its particular identity? According to biologists at the California Institute of Technology (Caltech), in the case of T cells-immune system cells that help destroy invading pathogens-the answer is when the cells begin expressing a particular gene called Bcl11b.

3 Jul 2010

Neogenix Oncology files patent application with USPTO for 16C3 antigen

Neogenix Oncology announced today that the company has filed a patent application with the U.S. Patent and Trade Office (USPTO) for the 16C3 antigen. The Company believes that this antigen is tumor specific for pancreatic and colorectal tumors; and, based on preliminary clinical data, may also have diagnostic utility as a biomarker for these cancers.

3 Jul 2010

IBM, University of Missouri collaborate to develop cloud computing environment for genomics research

IBM and the University of Missouri today announced a life sciences research initiative using IBM high performance computing technologies to advance the school's bioinformatics research projects. The goal of the initiative is to develop a first-of-a-kind cloud computing environment for genomics research collaboration at a regional level.

2 Jul 2010

Histone H1 phosphorylation involved in control of ribosomal RNA gene transcription

A protein that helps pack DNA into the cell nucleus has an important role in regulating gene activity, scientists report. The researchers found that the protein, histone H1, also takes part in the formation of ribosomes, the cellular workbenches on which all proteins are made.

2 Jul 2010

Plant extract effective against ulcerative colitis in mice

A South Dakota State University scientist's research shows an extract made from a food plant in the Brassica family was effective in alleviating signs of ulcerative colitis, an inflammatory bowel condition, in mice.

2 Jul 2010

Genes News and Research

New findings show why some people suffer from high levels of triglycerides

Olaparib shows promising results against inherited forms of breast and ovarian cancer

Rutgers researchers report genetic coding responsible for making QPM kernels sturdy

Scientists identify potential disease genes in humans and mice

MJFF announces $1.1M for projects to develop biomarker candidates for PD

Study shows gene-environment interaction in congenital heart disease

TGen develops G-SQZ technique for genomic data processing

Slow rate of living and reduced energy metabolism is sufficient to increase longevity: Study

Study finds additional targets for new therapies to treat advanced prostate cancer patients

Scientists discover nanoparticle to deliver DNA with minimum toxic effect

Hope for ovarian cancer patients not responding to conventional chemotherapy

Transplanted beta cells protect themselves by adapting to their new homes

Mount Sinai Hospital researchers discover new insights into genesis of stem cells

IRSF reports record turn-out at 11th Annual Rett syndrome Symposium

Study finds EPB41L3 'protector gene' inactivated in 65% of ovarian cancers

Further analysis on Bcl11b gene and T-cell behaviouur from Caltech Biologists

Neogenix Oncology files patent application with USPTO for 16C3 antigen

IBM, University of Missouri collaborate to develop cloud computing environment for genomics research

Histone H1 phosphorylation involved in control of ribosomal RNA gene transcription

Plant extract effective against ulcerative colitis in mice

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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