Genes News and Research

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Comprehensive view of the abnormal genetic landscape in lung cancer cells

An international team of scientists has announced the results of a systematic effort to map the genetic changes underlying lung cancer, the world's leading cause of cancer deaths.

5 Nov 2007

Inheriting two genetic mutations that can individually cause epilepsy may cancel each other

Inheriting two genetic mutations that can individually cause epilepsy might actually be "seizure-protective," said Baylor College of Medicine researchers in a report that appears online in the journal Nature Neuroscience.

5 Nov 2007

Manipulation of MOF enzyme may make tumors more sensitive to radiation therapy

To make tumors more sensitive to the killing power of radiation is a key aspiration for many radiation oncologists. Researchers at Washington University School of Medicine in St. Louis have uncovered new information that leads them closer to that goal.

5 Nov 2007

Regulation of TATA-less promoters

In their upcoming G&D paper, Dr. Robert Tjian (UC Berkeley) and colleagues reveal how histone gene expression is differentially regulated during Drosophila development.

2 Nov 2007

Mice predict the effectiveness of orally taken drugs

The amount of an orally taken drug that makes it to the site in the body at which it exerts its effects is much lower than the amount of an intravenously administered drug and it varies considerably between individuals.

2 Nov 2007

Genes identified to protect brassicas from damaging disease

Scientists have identified a new way to breed brassicas, which include broccoli, cabbage and oilseed rape, resistant to a damaging virus.

2 Nov 2007

Researchers discover new gene responsible for Brugada syndrome

Researchers at the University of Pittsburgh School of Medicine have identified a new gene responsible for a rare, inherited form of sudden cardiac arrest, known as Brugada syndrome.

1 Nov 2007

Blood gene expression signatures predict exposure levels

In a new study, researchers found they could detect toxic levels of acetaminophen in laboratory animals by analyzing gene expression in the blood.

1 Nov 2007

Harvard 'Brainbow' helps chart neural circuits

By activating multiple fluorescent proteins in neurons, neuroscientists at Harvard University are imaging the brain and nervous system as never before, rendering their cells in a riotous spray of colors dubbed a "Brainbow."

1 Nov 2007

Search for new uses for heroin and marijuana

The world's leading expert on the opium poppy has joined forces with researchers working on another infamous drug-producing plant – cannabis – in hopes of finding new uses for the much-maligned sources of heroin and marijuana.

1 Nov 2007

New genetic variant associated with prostate cancer in African-Americans

Two tiny genetic variations may provide the best clues yet for finding more precise ways to estimate prostate cancer risk and improve screening and early detection for men of African descent, report researchers from the University of Chicago and the Translational Genomics Research Institute, Phoenix, AZ, in the December 2007 issue of Genome Research, published early online.

1 Nov 2007

How one virus mimicks a normal cellular protein to replicate successfully

Both viruses and cancers subvert the growth-control machinery in a cell to serve their own needs.

1 Nov 2007

Gene, stem cell therapy only needs to be 50 percent effective to create a healthy heart

Heart disease is the leading cause of death in the United States and greatly affects the quality and length of life for individuals with specific forms of muscular dystrophy.

1 Nov 2007

The genetics of Candida albicans to be explored

A University of Arkansas postdoctoral researcher has received funding from the American Heart Association to study the genetics of a fungus that has the potential to kill people when they are most vulnerable - after organ transplants.

1 Nov 2007

HIV arrived in U.S. from Haiti 10 years earlier than previously believed

The most widespread HIV subtype outside Africa likely emerged in Haiti in the 1960s and arrived in the U.S. a few years later -- about 10 years earlier than previously believed -- according to a study published Tuesday in the Proceedings of the National Academy of Sciences, the Los Angeles Times reports.

31 Oct 2007

Scripps design new type of vaccine that could one day be used in humans to block the onset of infection

In hopes of combating the growing scourge of antibiotic-resistant bacteria, in particular drug-resistant staph bacteria, a team of scientists from the Scripps Research Institute has designed a new type of vaccine that could one day be used in humans to block the onset of infection.

31 Oct 2007