Genetic Engineering News and Research

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ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

A team of Gladstone scientists and their partners at Xyphos Biosciences, Inc. describe a new way of attacking cells infected by HIV in this week's issue of the journal Cell.

24 Oct 2019

New study identifies gene that causes intellectual disability syndrome

It used to take several years or sometimes decades to unequivocally identify the genes that cause rare human syndromes that affect very few individuals. Nowadays, however, human geneticists and fly and mouse biologists have the means to work together to integrate their data, which has significantly accelerated the pace of disease and gene discovery.

22 Oct 2019

Taste neurons could be controlling feeding behaviour find researchers

Researchers from the University of California, Riverside used a common fruit fly (Drosophila melanogaster) to find the association between taste neurons and control of feeding behaviours. They noted that if they genetically modulated these flies, they could make them selectively avoid certain chemicals including acids, bitter compounds, salty substances etc. The results of their study appeared in the October issue of the journal Cell Reports.

22 Oct 2019

Peptide-based nanoparticles can suppress pancreatic cancer growth without adverse effects

Despite advances in cancer survival, more than 90 percent of people with pancreatic cancer die within five years. Most patients with pancreatic tumors (and half of those with colorectal cancers) carry a mutation in the KRAS gene, which normally controls cell growth and death.

21 Oct 2019

University Of Minnesota opens clinical trial of first-of-its-kind NK cell cancer immunotherapy

A new cancer clinical trial has opened at the M Health Fairview University of Minnesota Medical Center that leverages the groundbreaking research on stem cells and natural killer cells done at the Masonic Cancer Center and applies it to attack acute myeloid leukemia and B-cell lymphoma.

21 Oct 2019

Creatine serves as a molecular battery to power killer T cells' fight against cancer

Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, serves as a molecular battery for immune cells by storing and distributing energy to power their fight against cancer, according to new UCLA research.

18 Oct 2019

Blue light and fruit flies: a warning for humans

A new study involving the fruit fly, Drosophila melanogaster, published in the journal npj Aging and Mechanisms of Disease, shows that when flies are kept in darkness, or in white light from which the blue spectrum has been excluded, they live longer, compared to flies kept in alternating 12-hour shifts of blue LED light and darkness. The reason appears to be a speeded-up version of aging; the brain cells, retinal cells and climbing ability, all suffer a breakdown.

18 Oct 2019

Adding plant-based compound to gene therapy could improve treatment outcomes

Gene therapy has broadened the treatment possibilities for those with immune system deficiencies and blood-based conditions, such as sickle cell anemia and leukemia.

17 Oct 2019

Scientists report evidence of immune response targeting brain cells in autism

Autism spectrum disorders affect one in 59 American children by age eight. With no known quantitative biological features, autism diagnoses are currently based on expert assessments of behavioral symptoms, including impaired social skills and communication, repetitive behaviors and restricted interests.

17 Oct 2019

Common bug repellent may chemically 'cloak' humans from malaria-carrying mosquitos

Since its invention during the Second World War for soldiers stationed in countries where malaria transmission rates were high, researchers have worked to pinpoint precisely how DEET actually affects mosquitos.

17 Oct 2019

Scientists successfully create age-resistant mice with hyper-long telomeres

Researchers have shown that it is possible to extend the life of mice by generating hyper-long telomeres, without using any gene modifying technologies.

17 Oct 2019

Genetically modified cotton could help fight against malnutrition

Cotton could be an unlikely ally in the fight against malnutrition, says GlobalData.

16 Oct 2019

Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage

When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel.

15 Oct 2019

The language of metabolites can be decoded with new genome technology

A team of microbiologists and genomicists has invented a genetic engineering tool that advances the study of secondary metabolites, which will expand our understanding of how microbes evolve.

14 Oct 2019

Brain protein plays a prominent role in the maintenance of chronic pain

A protein called RGS4 (Regulator of G protein signaling 4) plays a prominent role in the maintenance of long-term pain states and may serve as a promising new target for the treatment of chronic pain conditions, according to research conducted at the Icahn School of Medicine at Mount Sinai and published in print October 16, in The Journal of Neuroscience.

11 Oct 2019

Live-cell, genetically engineered pig skin used for temporary closure of a burn wound

Burn specialists at Massachusetts General Hospital announced today they have successfully used live-cell, genetically engineered pig skin (xenograft) for the temporary closure of a burn wound.

11 Oct 2019

Chewing gum to track fertility: Ovulaid

Infertility is a very potent cause of frustration and psychological problems such as anxiety and depression, as well as of high stress. Infertility or subfertility is defined by the World Health Organization as unsuccessful attempts to conceive for five or more years.

10 Oct 2019

Structural biology reveals 3D structure of asthma-linked receptor

A new study has laid bare the structure of a protein receptor called the CysLT1 receptor that is implicated in a range of allergic and cardiovascular conditions as well as some types of cancer. Published in Science Advances, the paper shows how the researchers used structural biology techniques to accomplish this feat.

10 Oct 2019

Suppressing brain immune cells might prevent or delay the onset of dementia

Messy tangles of a protein called tau can be found in the brains of people with Alzheimer's disease and some other neurodegenerative diseases. In Alzheimer's, the tangles coalesce just before tissue damage becomes visible in brain scans and people start to become forgetful and confused.

10 Oct 2019

New solution can limit spread of wild-released gene drives to target populations

By altering the heritability of certain traits, gene drive technologies have the potential to spread desired genes through wild populations.

10 Oct 2019

Genetic Engineering News and Research

ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

New study identifies gene that causes intellectual disability syndrome

Taste neurons could be controlling feeding behaviour find researchers

Peptide-based nanoparticles can suppress pancreatic cancer growth without adverse effects

University Of Minnesota opens clinical trial of first-of-its-kind NK cell cancer immunotherapy

Creatine serves as a molecular battery to power killer T cells' fight against cancer

Blue light and fruit flies: a warning for humans

Adding plant-based compound to gene therapy could improve treatment outcomes

Scientists report evidence of immune response targeting brain cells in autism

Common bug repellent may chemically 'cloak' humans from malaria-carrying mosquitos

Scientists successfully create age-resistant mice with hyper-long telomeres

Genetically modified cotton could help fight against malnutrition

Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage

The language of metabolites can be decoded with new genome technology

Brain protein plays a prominent role in the maintenance of chronic pain

Live-cell, genetically engineered pig skin used for temporary closure of a burn wound

Chewing gum to track fertility: Ovulaid

Structural biology reveals 3D structure of asthma-linked receptor

Suppressing brain immune cells might prevent or delay the onset of dementia

New solution can limit spread of wild-released gene drives to target populations

Biochemistry eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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