Genome News and Research

RSS

Scientists obtain detailed molecular structure of member of Tet family of enzymes

Scientists have obtained the first detailed molecular structure of a member of the Tet family of enzymes.

28 Dec 2013

Researchers study health consequences of RTE proliferation that occurs in aging tissues

The genomes of organisms from humans to corn are replete with "parasitic" strands of DNA that, when not suppressed, copy themselves and spread throughout the genome, potentially affecting health. Earlier this year Brown University researchers found that these "retrotransposable elements" were increasingly able to break free of the genome's control in cultures of human cells.

27 Dec 2013

THRIL could be novel biomarker for immune activation, potential target for inflammatory diseases

Sanford-Burnham Medical Research Institute scientists have discovered a new molecule that forms when certain white blood cells-macrophages-are stimulated in response to pathogens.

27 Dec 2013

Genetics of rheumatoid arthritis contributes to biology and drug discovery

The results of the largest international study to date into the genetic basis of rheumatoid arthritis shed light on the biology of the disease and provide evidence that large-scale genetic studies can assist in the identification of new drugs for complex disorders such as rheumatoid arthritis.

26 Dec 2013

Researchers uncover new genetic clue that contributes to increased risk of type 2 diabetes

An international team of researchers in Mexico and the United States has uncovered a new genetic clue that contributes to an increased risk of developing type 2 diabetes, particularly the elevated risk among Mexican and other Latin American populations.

26 Dec 2013

Researchers complete genomic analysis of cervical cancer in two patient populations

Researchers from the Boston area, Mexico, and Norway have completed a comprehensive genomic analysis of cervical cancer in two patient populations. The study identified recurrent genetic mutations not previously found in cervical cancer, including at least one for which targeted treatments have been approved for other forms of cancer.

25 Dec 2013

Fluidigm announces universal sample prep workflow for single-cell DNA sequencing

Fluidigm Corporation today announced a universal sample prep workflow for single-cell DNA sequencing that runs on its C1TM Single-Cell Auto Prep System. This workflow streamlines targeted, whole exome and whole genome sequencing in heterogeneous cell populations and enables researchers to discover and screen somatic mutations, such as SNP, small indels, and translocations.

24 Dec 2013

Genetic screening identifies genes driving resistance with guide RNA library

Researchers have developed a method to create a comprehensive library of mutations across all genes in the mouse genome. This library can be used to examine the role of every gene in different cell types.

23 Dec 2013

Six common diseases arise from DNA changes, finds new research

Many rare disorders are caused by gene mutation, like sickle cell anemia. Yet until now the underlying genetic cause of more common conditions - for example, rheumatoid arthritis - has evaded scientists for years.

22 Dec 2013

Neuroscience researchers discover gene that controls response to cocaine

UT Southwestern neuroscience researchers have identified a gene that controls the response to cocaine by comparing closely related strains of mice often used to study addiction and behavior patterns.

22 Dec 2013

Researchers map cell's complex genetic interactions to fix UV damaged DNA

Researchers at the University of California, San Diego School of Medicine, with colleagues in The Netherlands and United Kingdom, have produced the first map detailing the network of genetic interactions underlying the cellular response to ultraviolet (UV) radiation.

19 Dec 2013

Shared genetic risk for bipolar disorder and BMI

Researchers have found a positive association in the heritability of bipolar disorder and body mass index, supporting the theory that there is some interaction in the genetic mechanisms underlying these two traits.

19 Dec 2013

Abramson Cancer Center of the University of Pennsylvania celebrates 40th anniversary

This December marks the 40th anniversary of the Abramson Cancer Center of the University of Pennsylvania being designated a Comprehensive Cancer Center by the National Cancer Institute. To celebrate this momentous milestone, over 400 people gathered together early this month for an event recognizing the center's vast achievements in cancer research, patient care, and education during the last four decades.

19 Dec 2013

Aerobic glycolysis is a cause of malignancy, show Berkeley Lab researchers

Metabolism was lost in the shadows of cancer research for decades but has recently been reclaiming some of the spotlight. Now, Mina Bissell, Distinguished Scientist with Berkeley Lab's Life Sciences Division and a leading authority on breast cancer, has shown that aerobic glycolysis - glucose metabolism in the presence of oxygen - is not the consequence of the cancerous activity of malignant cells but is itself a cancerous event.

18 Dec 2013

NUS scientists open possible new route for treatment of spinal muscular atrophy

A recent study led by scientists from the National University of Singapore (NUS) opens a possible new route for treatment of Spinal Muscular Atrophy (SMA), a devastating disease that is the most common genetic cause of infant death and also affects young adults.

18 Dec 2013

E. coli evolution studies may lead to better treatments

Going back in time to compare evolutionary changes in several thousand generations of E. coli, a University of Houston biologist hopes to one day be able to isolate a bacterial pathogen and predict the likelihood it will become resistant to a particular antibiotic.

18 Dec 2013

New gene mutation helps doctors give more accurate diagnosis of mitochondrial myopathy

A new gene mutation which will help doctors give a more accurate diagnosis of a particular type of brain and muscle disease in children has been discovered for the first time by University of Leeds experts.

17 Dec 2013

Researchers discover direct evidence of genetic overlap between cognitive ability and schizophrenia

Investigators at The Feinstein Institute for Medical Research have discovered for the first time, direct evidence of a genetic overlap between schizophrenia and general cognitive ability. The findings are published online in Molecular Psychiatry.

17 Dec 2013

Mirimus develops enhanced tools for reversible gene suppression

Over the last decades, RNA interference (RNAi) has become an indispensable tool for functional genetic studies by harnessing the power of a cell intrinsic mechanism enabling reversible gene silencing.

17 Dec 2013

Scientists establish a goal of creating vaccine gene chip to speed up vaccine testing

Testing the efficacy of vaccines in clinical trials takes years, even decades. Yet challenging infections like HIV, malaria and dengue are striking today. To speed up vaccine testing, scientists at the Emory Vaccine Center have established a goal of creating a "vaccine gene chip."

17 Dec 2013

Genome News and Research

Scientists obtain detailed molecular structure of member of Tet family of enzymes

Researchers study health consequences of RTE proliferation that occurs in aging tissues

THRIL could be novel biomarker for immune activation, potential target for inflammatory diseases

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Researchers uncover new genetic clue that contributes to increased risk of type 2 diabetes

Researchers complete genomic analysis of cervical cancer in two patient populations

Fluidigm announces universal sample prep workflow for single-cell DNA sequencing

Genetic screening identifies genes driving resistance with guide RNA library

Six common diseases arise from DNA changes, finds new research

Neuroscience researchers discover gene that controls response to cocaine

Researchers map cell's complex genetic interactions to fix UV damaged DNA

Shared genetic risk for bipolar disorder and BMI

Abramson Cancer Center of the University of Pennsylvania celebrates 40th anniversary

Aerobic glycolysis is a cause of malignancy, show Berkeley Lab researchers

NUS scientists open possible new route for treatment of spinal muscular atrophy

E. coli evolution studies may lead to better treatments

New gene mutation helps doctors give more accurate diagnosis of mitochondrial myopathy

Researchers discover direct evidence of genetic overlap between cognitive ability and schizophrenia

Mirimus develops enhanced tools for reversible gene suppression

Scientists establish a goal of creating vaccine gene chip to speed up vaccine testing

Genetics & Genomics - Second Edition eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest News