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New glycan arrays discover autoimmunogenic activities of SARS-CoV

Researchers in New York City and Guangzhou, China applied the rapidly-developing carbohydrate microarray technology to study an inactivated SARS-coronavirus (SARS-CoV) vaccine and discovered autoimmunogenic activity of this newly identified human viral pathogen.

2 Aug 2004

Scientists discover genetic make-up of acne vulgaris

German scientists at the Gottingen Genomics Laboratory have discovered the genetic make-up of acne vulgaris. Acne vulgaris is a follicular disorder that affects susceptible pilosebaceous follicles, primarily of the face, neck, and upper trunk, and is characterized by both noninflammatory and inflammatory lesions.

29 Jul 2004

Framework for systematically incorporating epigenetic information into traditional genetic studies

Scientists at Johns Hopkins are calling for simultaneous evaluation of both genetic and epigenetic information in the search to understand contributors to such common diseases as cancer, heart disease and diabetes.

29 Jul 2004

New process that simplifies the production of proteins

F. William Studier, a biophysicist at the U.S. Department of Energy's Brookhaven National Laboratory, has won a 2004 R&D 100 award for developing a new process that simplifies the production of proteins in the widely used T7 gene expression system.

29 Jul 2004

Research using genomic testing reveals new information on flesh-eating bacteria

New research using nearly a dozen different genomic testing procedures has revealed unprecedented detail about the molecular characteristics and virulence of group A streptococcus (GAS), the “flesh-eating” bacteria, according to scientists at the Rocky Mountain Laboratories, part of the National Institute of Allergy and Infectious Diseases.

27 Jul 2004

Possible inherited component for lung cancer

Researchers have discovered a possible inherited component for lung cancer, a disease normally associated with external causes, such as cigarette smoking.

27 Jul 2004

Surprising differences in the DNA of normal cells from different people

A new study by Michael Wigler’s group at Cold Spring Harbor Laboratory has, in collaboration with researchers from Karolinska Institutet, revealed surprising differences in the DNA of normal cells from different people.

23 Jul 2004

New DNA microarray to speed bone disease research

Velcura Therapeutics has announced the development of a custom Affymetrix GeneChip(R) array that aids the development of bone disease therapies by enabling researchers to follow global changes in gene expression during human bone formation.

23 Jul 2004

Researchers discover a mechanism that blocks replication of a retrovirus

A team of scientists led by University of Georgia researchers has discovered a naturally occurring mechanism that blocks a critical step late in retrovirus replication.

21 Jul 2004

Genome decoded of distant relative of human pathogens

The Sanger Institute has completed the sequence and analysis of Erwinia carotovora subsp. atroseptica strain SCRI1043 (ATCC BAA-672).

21 Jul 2004

U.S. scientists have found the genetic basis for one form of sudden infant death syndrome

Sudden infant death syndrome, also known as cot death and crib death, is defined as the death of an infant between the ages of one month and one year which remains unexplained after a thorough postmortem, investigation of the death scene and review of the clinical history.

20 Jul 2004

Market research 'World RNAi Markets: Current and Future Outlook'

Gene silencing by RNAi has now been identified as a crucial technology for target validation and therapeutics. By targeting and interfering with messenger RNA (mRNA), RNAi technology blocks the expression of the proteins implicated in disease progression.

19 Jul 2004

First international server to analyze genetic diversity on a large scale

Researchers from the Universitat Autònoma de Barcelona have developed the first international server that allows the user to analyze genetic diversity on a large scale.

19 Jul 2004

DNA left overs, new mechanism for evolution

A team of researchers from the Universitat Autònoma de Barcelona (UAB) has discovered that transposons, small DNA sequences that travel through the genomes, can silence the genes adjacent to them by inducing a molecule called antisense RNA.

16 Jul 2004

The cancer risk from plutonium exposure

Plutonium may be many times more dangerous than previously thought. The cancer risk from exposure inside the body could be 10 times higher than is allowed for in calculating international safety limits.

15 Jul 2004

Scientists determine structure of staph, anthrax enzyme

Researchers at the U.S. Department of Energy's Argonne National Laboratory and the University of Chicago have determined the crystal structure of sortase B, an enzyme found in the bacteria that cause staph and anthrax. While an antibiotic is probably five to seven years away, the structure could provide the first clue in developing a treatment for the infections.

15 Jul 2004

Geographic variations in colour perception

It's long been known that color blindness is caused, usually in men, by changes in the red and green opsin genes, the genes that enable humans to perceive color.

9 Jul 2004

Chromatin array a new technology for examining DNA

A new technique for examining DNA is giving scientists a more detailed picture of which genes have the propensity for activation, offering a new tool for understanding how genes function and possibly for diagnosing disease.

8 Jul 2004

A Center for Human Genetics/Genomics has been established at the University of California

Established in UCSD Health Sciences, which includes the School of Medicine and School of Pharmacy and Pharmaceutical Sciences, the Center brings together UCSD faculty from multiple campus departments and schools including medicine, pharmacy, biology, biostatistics and mathematics.

30 Jun 2004

Gene mutation gradually causes devastating effects on cellular structure and function in Hutchinson-Gilford progeria syndrome

A mutation of the gene for lamin A protein gradually causes devastating effects on cellular structure and function in Hutchinson-Gilford progeria syndrome

29 Jun 2004